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Innovative immunotherapy harnesses natural killer T cells to combat solid tumors

In the fight against cancer, chimeric antigen receptor T cell (CAR-T) therapy has achieved notable success in treating blood cancers. However, it has been largely ineffective against solid tumors.

7 Oct 2024

Researchers use AI to reveal sex-based differences in glioblastoma prognosis

For years, cancer researchers have noticed that more men than women get a lethal form of brain cancer called glioblastoma.

7 Oct 2024

New study confirms brain's waste-clearance pathways in humans

Scientists have long theorized about a network of pathways in the brain that are believed to clear metabolic proteins that would otherwise build up and potentially lead to Alzheimer's and other forms of dementia. But they had never definitively revealed this network in people - until now.

7 Oct 2024

Early blood test can predict treatment response and survival prospects in metastatic prostate cancer

A blood test, performed when metastatic prostate cancer is first diagnosed, can predict which patients are likely to respond to treatment and survive the longest.

7 Oct 2024

New insights into immune mechanisms that prevent cancer metastasis

Metastatic disease - when cancer spreads from the primary tumor to other parts of the body - is the cause of most cancer deaths.

7 Oct 2024

When CDK12/13 stalls, healthy prostate cells take a malignant turn

CDK12 is established as a tumor suppressor in prostate cancer, with its loss driving aggressive disease and creating vulnerabilities for targeted therapies.

7 Oct 2024

New cell therapy offers effective treatment for patients with T-cell acute lymphoblastic leukemia

A new cell therapy, targeting CD7 on leukaemia cells, gives a potentially effective treatment for patients with T-cell acute lymphoblastic leukaemia (T-ALL) who have exhausted all standard treatment options.

7 Oct 2024

CheekAge: Next-gen epigenetic clock accurately predicts mortality risk

Researchers developed CheekAge, an epigenetic clock based on buccal cells, and found it predicted mortality risk with significant accuracy. This study validates CheekAge as a reliable aging biomarker, outperforming first-generation clocks.

6 Oct 2024

Researchers reveal mechanisms of how CDK12 alterations drive prostate cancer development

When researchers at the University of Michigan Rogel Cancer Center first identified a new subtype of aggressive prostate cancer, they knew they needed to understand how this genetic alteration was driving cancer and how to target it with treatment.

4 Oct 2024

New drug could extend the lives of breast cancer patients

LMU researchers have successfully tested a new drug which can significantly extend the lives of breast cancer patients.

4 Oct 2024

Engineered E. coli shows promise in cancer immunotherapy

Recent research has shown that certain forms of E. coli bacteria tend to colonize hypoxic areas of the body, including tumors, suggesting they might be playing a role in cancer therapeutics.

4 Oct 2024

New insights into the role of gamma-delta T cells across 33 cancer types revealed

A new study published in Cell Press reveals critical insights into the role of gamma-delta T cells across 33 cancer types, shedding light on their potential as clinical biomarkers and therapeutic targets in cancer treatment.

4 Oct 2024

Cancer Research UK backs study to develop preventive ovarian cancer vaccine

In this study, the Cancer Research UK-funded scientists will establish the targets for the vaccine. They will find out which proteins on the surface of early-stage ovarian cancer cells are most strongly recognized by the immune system and how effectively the vaccine kills mini-models of ovarian cancer called organoids.

4 Oct 2024

NIH supports research on non-opioid pain relief for oral cancer patients

The School of Dentistry at The University of Texas Health Science Center at San Antonio (UT Health San Antonio) earned the first National Institutes of Health grant under its new Center for Pain Therapeutics and Addiction Research, addressing pain in patients with head and neck carcinoma.

4 Oct 2024

KiNet web portal enhances study of kinase functions in cellular signaling pathways

Researchers from the Icahn School of Medicine at Mount Sinai have introduced KiNet, an interactive web portal designed to explore kinase-substrate interactions in human cellular systems. These interactions play a vital role in modulating complex signaling pathways that control various cellular processes, such as cell growth, differentiation, and response to environmental stimuli.

4 Oct 2024

Innovative blood test for lung cancer offers faster and more sensitive diagnosis

A new way of diagnosing lung cancer with a blood draw is 10 times faster and 14 times more sensitive than earlier methods, according to University of Michigan researchers.

3 Oct 2024

Diagnostic performance of GPT-4 in analyzing radiology findings from brain tumors

GPT-4 demonstrates diagnostic capabilities in brain radiology, achieving 73% accuracy for final diagnoses and 94% for differential diagnoses in recent research.

3 Oct 2024

Florida breast cancer foundation funds two UCF projects to combat breast cancer

As Breast Cancer Awareness Month begins, two College of Medicine cancer researchers have received statewide grants to support their innovative projects to fight a disease that strikes one in eight American women.

3 Oct 2024

New study links pulmonary carcinoid aggressiveness to TERT gene activation

Pulmonary carcinoids are rare tumors of the lung with extremely different clinical courses. In many patients, they behave like benign tumors; surgical removal of the tumor leads to a complete cure. However, some patients experience aggressive growth and spread (metastasis) of the tumor with poor chances of recovery. The biological causes of these different forms of the disease are still unknown.

3 Oct 2024

The threat of serous uterine cancer: A new perspective

Most uterine cancers have excellent five-year survival rates – up to 95% for localized cancer. Serous uterine cancer is an exception, with five-year survival rates of 35% to 50% for stage 1 or 2 cancer.

3 Oct 2024

Tumor News and Research

Innovative immunotherapy harnesses natural killer T cells to combat solid tumors

Researchers use AI to reveal sex-based differences in glioblastoma prognosis

New study confirms brain's waste-clearance pathways in humans

Early blood test can predict treatment response and survival prospects in metastatic prostate cancer

New insights into immune mechanisms that prevent cancer metastasis

When CDK12/13 stalls, healthy prostate cells take a malignant turn

New cell therapy offers effective treatment for patients with T-cell acute lymphoblastic leukemia

CheekAge: Next-gen epigenetic clock accurately predicts mortality risk

Researchers reveal mechanisms of how CDK12 alterations drive prostate cancer development

New drug could extend the lives of breast cancer patients

Engineered E. coli shows promise in cancer immunotherapy

New insights into the role of gamma-delta T cells across 33 cancer types revealed

Cancer Research UK backs study to develop preventive ovarian cancer vaccine

NIH supports research on non-opioid pain relief for oral cancer patients

KiNet web portal enhances study of kinase functions in cellular signaling pathways

Innovative blood test for lung cancer offers faster and more sensitive diagnosis

Diagnostic performance of GPT-4 in analyzing radiology findings from brain tumors

Florida breast cancer foundation funds two UCF projects to combat breast cancer

New study links pulmonary carcinoid aggressiveness to TERT gene activation

The threat of serous uterine cancer: A new perspective

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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