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Pinaverium offers quick relief from IBS symptoms

Pinaverium offers quick and effective relief of irritable bowel syndrome (IBS) symptoms, according to clinical trial results published in Clinical Gastroenterology and Hepatology, the official clinical practice journal of the American Gastroenterological Association.

30 Jun 2015

UC San Diego epidemiologist receives $1.5 million grant for research on HIV, substance abuse

Dan Werb, PhD, an internationally noted epidemiologist at University of California, San Diego School of Medicine, has been named one of four inaugural recipients of the Avenir Award, a prestigious $1.5 million research grant from the U.S. National Institute on Drug Abuse, part of the National Institutes of Health (NIH).

30 Jun 2015

Pharma Two B reports positive results from P2B001 Phase IIb study for treatment of early stage PD

Pharma Two B Ltd., a privately held company developing innovative therapeutics based on previously approved drugs, announced today the successful results of the company's Phase IIb pivotal study of P2B001 for the treatment of early stage Parkinson's Disease (PD).

30 Jun 2015

Kalorama Information: NGS diagnostics can detect any number of genetic variants

Next generation sequencing may be able to bypass some of the downside of molecular testing and in doing so earn its place in clinical testing, according to Kalorama Information.

30 Jun 2015

Telesta submits Biologics License Application for MCNA to FDA

Telesta Therapeutics Inc. announced today that it has submitted electronically, through its U.S. agent, a Biologics License Application (BLA) to the United States Food and Drug Administration for MCNA. MCNA is Telesta's novel biologic immunotherapeutic for the treatment of high-risk non-muscle invasive bladder cancer patients who have failed first-line BCG therapy.

30 Jun 2015

First participant enrolled in RepliCel's RCT-01 Phase 1/2 clinical trial for treatment of chronic tendinosis

RepliCel Life Sciences Inc., a clinical stage regenerative medicine company focused on the development of autologous cell therapies, announced today that the first participant in its Phase 1/2 clinical trial of RCT-01, being tested for the treatment of chronic unilateral Achilles tendinosis, has been enrolled and their tissue biopsy sent for processing prior to intra-tendon ultrasound-guided injections.

30 Jun 2015

Hepatic ALT flares linked to HBsAg clearance

Hepatic alanine aminotransferase flares are associated with rapid decline and greater annual reductions of hepatitis B surface antigen in patients with chronic hepatitis B virus infection who achieve HBsAg seroclearance, say Japanese researchers.

30 Jun 2015

New stroke treatment guidelines recommend use of stent retrievers as first-line treatment for eligible patients

Today, the American Heart Association/American Stroke Association published new stroke treatment guidelines that recommend the use of stent retriever technology – such as Medtronic plc’s SolitaireTM stent retriever device – in conjunction with the current standard of care, IV-tPA, as a first-line treatment for eligible patients.

30 Jun 2015

Aeterna Zentaris recruits patients for ZoptEC Phase 3 study in women with advanced endometrial cancer

Aeterna Zentaris Inc. today announced it has reached its goal of recruiting 500 patients for its pivotal Phase 3 ZoptEC (Zoptarelin Doxorubicin in Endometrial Cancer) clinical study with zoptarelin doxorubicin in women with advanced, recurrent or metastatic endometrial cancer.

30 Jun 2015

Case report published on first use of 3D printed scaffold for periodontal tissue engineering

Today, the International and American Associations for Dental Research published a case report on the first application of a 3D printed scaffold for periodontal tissue engineering in a human patient, along with a review of 3D printing for oral and craniofacial tissue engineering.

30 Jun 2015

Majority of men who use violence against female partner struggle with serious mental health issues

The majority of men who use violence towards their partner struggle with serious mental health issues. We need to look at more than just the power relations between the sexes in order to understand and prevent domestic violence, says researcher.

30 Jun 2015

New species of tRNA-derived small RNAs contribute to cell proliferation in cancer

Since their discovery in the 1950s, transfer RNAs (tRNAs) have been best known for their role in helping the cell make proteins from messenger RNA templates. However, recent studies have led to a previously-unsuspected concept that tRNAs are not always the end product; namely, they further serve as a source of small RNAs.

30 Jun 2015

Wistar Institute study shows that PI3K inhibitors may make a patient's cancer even worse

The enzyme phosphatidylinositol-3 kinase (PI3K) appears to be exploited in almost every type of human cancer, making it the focus of considerable interest as a therapeutic target, with many PI3K-inhibiting drugs currently in various stages of clinical development. However, PI3K inhibitors have only shown modest clinical activity with patients who receive these drugs experiencing very little improvement in survival.

30 Jun 2015

New discovery could lead to personalized treatment for colon cancer

A UNC Lineberger Comprehensive Cancer Center discovery of just how a certain tumor suppressor molecule works to prevent tumor growth could lead to a personalized treatment approach for colon cancer.

30 Jun 2015

Study may predict which glioblastoma patients may respond well to dasatinib drug treatment

Clinicians testing the drug dasatinib, approved for several blood cancers, had hoped it would slow the aggressive growth of the deadly brain cancer glioblastoma; however, clinical trials to date have not found any benefit. Researchers at Mayo Clinic, who conducted one of those clinical trials, believe they know why dasatinib failed — and what to do about it.

30 Jun 2015

Exhausted army of immune cells may damage the very body they are supposed to protect

An 'exhausted' army of immune cells may not be able to fight off infection, but if its soldiers fight too hard they risk damaging the very body they are meant to be protecting, suggests new research from the University of Cambridge.

30 Jun 2015

Axovant Sciences accepts two presentations at Alzheimer's Association International Conference 2015

Axovant Sciences Ltd., a leading clinical-stage biopharmaceutical company focused on the treatment of dementia, today announced the acceptance of two presentations at the Alzheimer's Association International Conference 2015 (AAIC) being held in Washington, D.C. from July 18-23, 2015.

30 Jun 2015

Canada's first human gene therapy trial for choroideremia now underway at Royal Alexandra Hospital

Canada's first human gene therapy trial for eyes -- the replacement of a faulty gene with a healthy one -- is now underway at the Royal Alexandra Hospital to preserve and potentially restore vision for people with a genetic disorder that leaves them blind by middle age.

30 Jun 2015

Study on fruit flies, brewer's yeast may provide clues about cause of Spinal Muscular Atrophy

Scientists at the University of Malta and the Institut de Génétique Moléculaire de Montpellier (CNRS/Université de Montpellier) have shown that fruit flies and brewer's yeast can reveal clues about the cause of Spinal Muscular Atrophy (SMA), the most common genetic killer of infants.

30 Jun 2015

Specialized mental health treatment can benefit children from poor nations

A specific type of talk therapy dispensed in the developing world to orphans and other vulnerable children who experienced trauma such as sexual and domestic abuse showed dramatic results, despite being administered by workers with little education, new research shows.

30 Jun 2015

Therapy News and Research

Pinaverium offers quick relief from IBS symptoms

UC San Diego epidemiologist receives $1.5 million grant for research on HIV, substance abuse

Pharma Two B reports positive results from P2B001 Phase IIb study for treatment of early stage PD

Kalorama Information: NGS diagnostics can detect any number of genetic variants

Telesta submits Biologics License Application for MCNA to FDA

First participant enrolled in RepliCel's RCT-01 Phase 1/2 clinical trial for treatment of chronic tendinosis

Hepatic ALT flares linked to HBsAg clearance

New stroke treatment guidelines recommend use of stent retrievers as first-line treatment for eligible patients

Aeterna Zentaris recruits patients for ZoptEC Phase 3 study in women with advanced endometrial cancer

Case report published on first use of 3D printed scaffold for periodontal tissue engineering

Majority of men who use violence against female partner struggle with serious mental health issues

New species of tRNA-derived small RNAs contribute to cell proliferation in cancer

Wistar Institute study shows that PI3K inhibitors may make a patient's cancer even worse

New discovery could lead to personalized treatment for colon cancer

Study may predict which glioblastoma patients may respond well to dasatinib drug treatment

Exhausted army of immune cells may damage the very body they are supposed to protect

Axovant Sciences accepts two presentations at Alzheimer's Association International Conference 2015

Canada's first human gene therapy trial for choroideremia now underway at Royal Alexandra Hospital

Study on fruit flies, brewer's yeast may provide clues about cause of Spinal Muscular Atrophy

Specialized mental health treatment can benefit children from poor nations

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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