Cell Death News and Research

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Findings may contribute to better understanding of aging and cancer development

A team of researchers led by Dr. Dennis Kappei, a Special Fellow from the Cancer Science Institute of Singapore at the National University of Singapore, has discovered the role of the protein ZBTB48 in regulating both telomeres and mitochondria, which are key players involved in cellular aging.

14 Jun 2017

Study examines how sex alters time-course of inflammation in the brain after TBI

Male mice have much greater brain distress in the week following a traumatic brain injury (TBI) than female mice, including skyrocketing inflammation and nerve cell death, say researchers at Georgetown University Medical Center.

13 Jun 2017

Magnetic nanoparticle aggregates can induce death of cancer cells

An international team in which a UPM researcher is involved has shown that it is possible to mechanically destroy cancer cells by rotating magnetic nanoparticles attached to them in elongated aggregates.

13 Jun 2017

Genetic manipulation of exosomes may offer new therapeutic approach to treating pancreatic cancer

Genetic manipulation of exosomes, virus-sized particles released by all cells, may offer a new therapeutic approach to treating pancreatic cancer, according to a study at The University of Texas MD Anderson Cancer Center.

8 Jun 2017

Study reveals cancer-fighting power of onions

The next time you walk down the produce aisle of your grocery store, you may want to reach for red onions if you are looking to fight off cancer.

7 Jun 2017

Combination therapy shows potential for effective treatment of RAS-mutant cancers

A study at The University of Texas MD Anderson Cancer Center has shown promise for effective treatment of therapy-resistant cancers caused by a mutation of the RAS gene found in many cancers.

2 Jun 2017

Orlando Health deploys NanoKnife as new weapon in battle against pancreatic cancer

Oncologists at UF Health Cancer Center Orlando Health are deploying NanoKnife as a new weapon in the battle against pancreatic cancer.

1 Jun 2017

Common, inexpensive chemical could slow aging of human skin, research suggests

New work from the University of Maryland suggests that a common, inexpensive and safe chemical could slow the aging of human skin.

31 May 2017

Men appear to have worse chemotherapy-induced cardiomyopathy than women, research shows

Men seem to have worse chemotherapy-induced cardiomyopathy than women despite receiving similar cancer treatments, according to research presented today at EuroCMR 2017.

25 May 2017

Study points to new pharmacologic approach to target chemo-resistant lung cancer

Patients with non-small cell lung cancer (NSCLC) often respond to standard chemotherapy, only to develop drug resistance later, and with fatal consequences.

23 May 2017

VCU study provides new view about HPV-related head and neck cancers

Much of what we thought we knew about the human papilloma virus (HPV) in HPV-related head and neck cancers may be wrong, according to a newly published study by Virginia Commonwealth University researchers that analyzed data from The Human Cancer Genome Atlas.

23 May 2017

New understanding about brain proteins could lead to effective therapies for dementia

A research team from the University of Plymouth, University of Southampton and the Alexander Fleming Biomedical Sciences Research Center, Vari, Greece, have studied two structurally-similar proteins in the adult brain and have found that they play distinct roles in the development of dementia.

19 May 2017

Trans-fatty acids promote cell death in a more direct manner than previously thought

Tohoku University researchers have found that trans-fatty acids promote cell death in a more direct manner than previously thought, leading to the development of atherosclerosis, a major cause of heart attacks and strokes.

18 May 2017

Freiburg scientists show that enzymes can be activated through electrical stimulation of cell membrane

The enzymes nitric oxide (NO) synthase (NOS1) and protein kinase C (PKC) play an important role in a variety of signal transfer processes in neurons of the brain, as well as in many cell types of other organs.

18 May 2017

Electrical stimulation of the brain may help preserve visual neurons from cell death after injury

Electrical stimulation of the brain by applying current to the eye may help retinal nerve cells to survive injury. While these neurons may not be restored to full function, they are prevented from dying. But to achieve survival, their interconnections, the dendritic tree, needs to disconnect rapidly for the protective action to unfold.

18 May 2017

Biochemical self-destruct trigger guards brain cells when fighting against West Nile virus

In a turnabout, a biochemical self-destruct trigger found in many other types of cells appears to guard the lives of brain cells during an infection with West Nile virus.

18 May 2017

Study prompts further assessment of tomato extracts’ use in gastric cancer prevention

A new study shows that whole tomato extracts from two different Southern Italy cultivars inhibit gastric cancer cell growth and malignant features, paving the way for future studies aimed at implementing lifestyle habits not only for prevention but potentially as a support to conventional therapies.

15 May 2017

New spherical nucleic acid drug crosses blood-brain barrier to target brain tumors in animals

The first drug using spherical nucleic acids to be systemically given to humans has been developed by Northwestern University scientists and approved by the Food and Drug Administration as an investigational new drug for an early-stage clinical trial in the deadly brain cancer glioblastoma multiforme.

12 May 2017

Suppression of thyroid hormone receptor protects cone cells in mouse models of retinal diseases

New research published online in The FASEB Journal suggests that the suppression of thyroid hormone receptor activity locally in the retina protects cone photoreceptor cells in mouse models of human retinal degenerative diseases

11 May 2017

Troponin elevations can occur in the absence of classic myocardial infarction, study shows

Elevated cardiac troponin, a diagnostic marker of damage to the heart, may occur even if a patient has not had a heart attack, according to a study published in JACC: Basic to Translational Science.

9 May 2017

Cell Death News and Research

Findings may contribute to better understanding of aging and cancer development

Study examines how sex alters time-course of inflammation in the brain after TBI

Magnetic nanoparticle aggregates can induce death of cancer cells

Genetic manipulation of exosomes may offer new therapeutic approach to treating pancreatic cancer

Study reveals cancer-fighting power of onions

Combination therapy shows potential for effective treatment of RAS-mutant cancers

Orlando Health deploys NanoKnife as new weapon in battle against pancreatic cancer

Common, inexpensive chemical could slow aging of human skin, research suggests

Men appear to have worse chemotherapy-induced cardiomyopathy than women, research shows

Study points to new pharmacologic approach to target chemo-resistant lung cancer

VCU study provides new view about HPV-related head and neck cancers

New understanding about brain proteins could lead to effective therapies for dementia

Trans-fatty acids promote cell death in a more direct manner than previously thought

Freiburg scientists show that enzymes can be activated through electrical stimulation of cell membrane

Electrical stimulation of the brain may help preserve visual neurons from cell death after injury

Biochemical self-destruct trigger guards brain cells when fighting against West Nile virus

Study prompts further assessment of tomato extracts’ use in gastric cancer prevention

New spherical nucleic acid drug crosses blood-brain barrier to target brain tumors in animals

Suppression of thyroid hormone receptor protects cone cells in mouse models of retinal diseases

Troponin elevations can occur in the absence of classic myocardial infarction, study shows

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