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UNC study shows promise for uncovering true mechanisms of human stem cell biology

For the first time, researchers at the University of North Carolina at Chapel Hill have isolated adult stem cells from human intestinal tissue.

5 Apr 2013

Scientists develop a new way to generate induced pluripotent stem cell lines from human fibroblasts

A team of New York Stem Cell Foundation (NYSCF) Research Institute scientists led by David Kahler, PhD, NYSCF Director of Laboratory Automation, have developed a new way to generate induced pluripotent stem (iPS) cell lines from human fibroblasts, acquired from both healthy and diseased donors.

4 Apr 2013

Engineers develop prototype telerobotic platform for bladder cancer treatment

Although bladder cancer is the sixth most common form of cancer in the U.S. and the most expensive to treat, the basic method that doctors use to treat it hasn't changed much in more than 70 years.

3 Apr 2013

Researchers identify link between immune response and blood clotting

Rice University researchers have found an unexpected link between a protein that triggers the formation of blood clots and other proteins that are essential for the body's immune system.

2 Apr 2013

Research findings shed light on molecular processes involved in initial stages of PD

In a mouse model of early Parkinson's disease, animals displayed movement deficits, loss of tyrosine-hydroxylase (TH)-positive fibers in the striatum, and astro-gliosis and micro-gliosis in the substantia nigra (SN), without the loss of nigral dopaminergic neurons.

2 Apr 2013

AACR recognizes scientists whose contributions to cancer field have extraordinary impact

Five University of California, San Diego scientists and professors are among the first class of the Fellows of the American Association for Cancer Research Academy, created to recognize researchers whose scientific contributions have propelled significant innovation and progress against cancer.

29 Mar 2013

Prostate cancer prognosis tables: an interview with Dr John B. Eifler, Brady Urological Institute of Johns Hopkins

Prostate cancer is the most common cancer in men. Despite many advances in diagnosis and treatment over the past two decades, it remains the second most common cause of cancer related death in men.

28 Mar 2013

Johns Hopkins scientists identify DNA-damaging substances in food

In a laboratory study pairing food chemistry and cancer biology, scientists at the Johns Hopkins Kimmel Cancer Center tested the potentially harmful effect of foods and flavorings on the DNA of cells.

28 Mar 2013

Non-invasive imaging technique for detecting cancer presented at BioPIC 2013

A non-invasive imaging technique which may help in the earlier detection of cancer is among the innovative research being presented at BioPIC 2013, a BioPhotonics and Imaging Conference, taking place in Castleknock Hotel and Country Club, Dublin from 25th - 27th March.

27 Mar 2013

German Research Foundation sets up eight new Research Units

The Deutsche Forschungsgemeinschaft is establishing eight new Research Units. This was decided by the DFG Senate during its 2013 March meeting in Bonn.

20 Mar 2013

New molecular sensor technique for cancer therapy detects lactate levels in individual cells

Cancer cells break down sugars and produce the metabolic acid lactate at a much higher rate than normal cells. This phenomenon provides a telltale sign that cancer is present, via diagnostics such as PET scans, and possibly offers an avenue for novel cancer therapies.

16 Mar 2013

Abiraterone's anti-androgenic properties may stop tumor growth of CRPC, says prize-winning Dutch study

As part of an EU-supported IMI-PREDECT consortium, a Dutch study showed that anti-androgenic properties of the drug abiraterone may provide an additional mechanism of action in blocking tumour growth of castration resistant prostate cancer (CRPC).

16 Mar 2013

Researchers develop single molecule test for detecting methylated DNA

Collaborators from Mayo-Illinois Alliance for Technology Based Healthcare have developed a new, single molecule test for detecting methylated DNA. Methylation -- the addition of a methyl group of molecules to a DNA strand -- is one of the ways gene expression is regulated.

15 Mar 2013

UNM scientists identify chemical compound that appears to control cell metastases

It's the spread of the original cancer tumor that kills most people. That's why cancer researchers vigorously search for drugs that can prevent metastases, the spread of cancer. The research team co-led by Angela Wandinger-Ness, PhD, and Larry Sklar, PhD, at the University of New Mexico Cancer Center has found a chemical compound that appears to control cell migration and adhesion, two important characteristics of metastatic cancer cells.

14 Mar 2013

Researchers discover likely origin of epithelial ovarian cancer

Cornell University researchers have discovered a likely origin of epithelial ovarian cancer (ovarian carcinoma), the fifth leading cause of cancer death among women in the United States.

7 Mar 2013

Scientists succeed in direct observation of microorganisms feeding on the intestinal mucosa

The microbiology team of David Berry, Alexander Loy and Michael Wagner from the Faculty of Life Sciences, in collaboration with scientists at the Max F. Perutz Laboratories and with the help of NanoSIMS technology, has for the first time succeeded in directly observing microorganisms feeding on the intestinal mucosa.

6 Mar 2013

Insight into cellular operations that give extraordinary staying power to S. mansoni

From the point of view of its ultimate (human) host, the parasitic flatworm Schistosoma mansoni has a gruesome way of life. It hatches in feces-tainted water, grows into a larva in the body of a snail and then burrows through human skin to take up residence in the veins. Once there, it grows into an adult, mates and, if it's female, starts laying eggs. It can remain in the body for decades.

26 Feb 2013

Schistosome stem cells could explain how the worms survive for so many years

The parasites that cause schistosomiasis, one of the most common parasitic infections in the world, are notoriously long-lived. Researchers have now found stem cells inside the parasite that can regenerate worn-down organs, which may help explain how they can live for years or even decades inside their host.

24 Feb 2013

Blaze Bioscience completes $8.5 million Series A financing

Blaze Bioscience, Inc., a biotechnology company dedicated to developing innovative products to improve the lives of cancer patients, today announced the completion of a Series A financing totaling $8.5 million and bringing the total funds raised since inception to $9.8 million.

22 Feb 2013

USP evaluates Raman device's potential to detect counterfeit and substandard medicines

With substandard and counterfeit medicines a dangerous and growing problem in the developing world and elsewhere, identifying new technologies to detect such drugs is an urgent matter. In a new study published in the Journal of Pharmaceutical and Biomedical Analysis, scientists from the U.S. Pharmacopeial Convention (USP) evaluated a handheld Raman device's potential to detect counterfeit and substandard medicines.

21 Feb 2013