Peptides News and Research

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PGFX Patent Holdings acquires proprietary methods, devices, intellectual property from Orogen Biosciences

On Friday, April 18th PGFX Patent Holdings, operating as Heritage Biosciences, LLC made an asset acquisition of proprietary methods, devices and intellectual property from Orogen Biosciences, Inc.

31 May 2014

Researchers create initial catalog of human proteome, identify 193 novel proteins

Striving for the protein equivalent of the Human Genome Project, an international team of researchers has created an initial catalog of the human "proteome," or all of the proteins in the human body.

29 May 2014

Study: Apolipoprotein E mimetic peptide protects against diffuse brain injury

Because the majority of patients with diffuse brain injury are not suitable candidates for surgery, neuroprotective agents are of great importance.

28 May 2014

Half-life extension technology: an interview with Dermot Pearson, Novozymes Biopharma

A drug's half-life indicates how long a substance will remain active in the body. It is essentially the period of time that it takes for the concentration of the amount of the drug to be reduced by half, and therefore, determines how frequently a drug needs to be administered to maintain its therapeutic effect.

27 May 2014

Peptide antibodies hit immune-response-stifling MDSCs without harming other vital cells

Scientists have found a way to target elusive cells that suppress immune response, depleting them with peptides that spare other important cells and shrink tumors in preclinical experiments, according to a paper published online by Nature Medicine.

26 May 2014

Pain receptors may hold key to treating obesity, diabetes and improving metabolic health

Blocking a pain receptor in mice not only extends their lifespan, it also gives them a more youthful metabolism, including an improved insulin response that allows them to deal better with high blood sugar.

23 May 2014

Researchers identify small molecule that prevents bacteria from forming into infectious biofilms

Researchers at the University of British Columbia have identified a small molecule that prevents bacteria from forming into biofilms, a frequent cause of infections.

23 May 2014

Researcher receives $1.5M grant from NIH to find clues into causes of Alzheimer's

Alzheimer's is a progressive brain disease that affects older adults, slowly destroys their memories and may cause dementia. According to estimates from the National Institutes of Health (NIH), the disease may affect as many as 5.1 million Americans.

22 May 2014

GSA announce winners of GSA Poster Awards at 55th Annual Drosophila Research Conference

The Genetics Society of America (GSA) and the Drosophila research community are pleased to announce the winners of GSA Poster Awards at the 55th Annual Drosophila Research Conference, which took place in San Diego, March 26-30, 2014.

21 May 2014

Study reveals surprising relationships between diet and release of hormones that suppress eating

By comparing how gut microbes from human vegetarians and grass-grazing baboons digest different diets, researchers have shown that ancestral human diets, so called "paleo" diets, did not necessarily result in better appetite suppression.

20 May 2014

Renal dysfunction affects NT-proBNP predictive thresholds in pulmonary hypertension

N-terminal pro-brain natriuretic peptide remains a valid predictor in patients with pulmonary arterial hypertension who have concomitant renal dysfunction, say researchers.

19 May 2014

PARADIGM-HF trial of LCZ696 for chronic heart failure stopped early for benefit

The PARADIGM-HF trial has been stopped early for a benefit to patients that was overwhelmingly statistically significant.

19 May 2014

Urine test can indicate presence of venous thromboembolism in patients at risks for clots

A new study by researchers from California and Canada indicates a simple urine test can indicate the presence of venous thromboembolism, a blood clot that has broken free from its point of origin and which travels through the bloodstream, eventually lodging in a vein.

19 May 2014

Study: E-cigarettes appear to increase virulence of drug- resistant and life-threatening bacteria

Despite being touted by their manufacturers as a healthy alternative to cigarettes, e-cigarettes appear in a laboratory study to increase the virulence of drug- resistant and potentially life-threatening bacteria, while decreasing the ability of human cells to kill these bacteria

19 May 2014

Nanogel heals burn wounds faster

Researchers at the Institute of Bioengineering and Nanotechnology have developed a nanogel that can accelerate the healing of burn wounds to minimize the risk of infection and scarring. The technology is based on IBN’s proprietary self-assembling ultrashort peptide technology, which are short sequences of amino acids.

16 May 2014

Researchers show how cone snails venom inhibits neuronal calcium channels to reduce neuropathic pain

The venom from marine cone snails, used to immobilize prey, contains numerous peptides called conotoxins, some of which can act as painkillers in mammals. A recent study in The Journal of General Physiology provides new insight into the mechanisms by which one conotoxin, Vc1.1, inhibits pain.

15 May 2014

Anti-depressants could slow onset of Alzheimer's disease

A University of Pennsylvania researcher has discovered that the common selective serotonin reuptake inhibitor (SSRI) citalopram arrested the growth of amyloid beta, a peptide in the brain that clusters in plaques that are thought to trigger the development of Alzheimer's disease (AD).

15 May 2014

Investigators find effective treatment for life-threatening angioedema attacks in ED

Investigators at the University of Cincinnati have found a safe and effective treatment for life-threatening angioedema attacks in the emergency department.

15 May 2014

Novozymes Biopharma, ThioLogics to collaborate on drug-albumin conjugation platform

Novozymes Biopharma has entered a new collaboration with UK-based biotechnology company, ThioLogics. The collaboration brings together Novozymes' modified recombinant human albumin (rAlbumin) Veltis technology, with ThioLogics' site-specific next generation maleimide conjugation platform. This allows Novozymes to offer the pharma industry serum stable albumin drug conjugates with enhanced pharmacokinetic and/or targeting capabilities.

14 May 2014

Scientists discover novel protein fragments that may protect against Alzheimer's disease

The devastating loss of memory and consciousness in Alzheimer's disease is caused by plaque accumulations and tangles in neurons, which kill brain cells.

14 May 2014

Peptides News and Research

PGFX Patent Holdings acquires proprietary methods, devices, intellectual property from Orogen Biosciences

Researchers create initial catalog of human proteome, identify 193 novel proteins

Study: Apolipoprotein E mimetic peptide protects against diffuse brain injury

Half-life extension technology: an interview with Dermot Pearson, Novozymes Biopharma

Peptide antibodies hit immune-response-stifling MDSCs without harming other vital cells

Pain receptors may hold key to treating obesity, diabetes and improving metabolic health

Researchers identify small molecule that prevents bacteria from forming into infectious biofilms

Researcher receives $1.5M grant from NIH to find clues into causes of Alzheimer's

GSA announce winners of GSA Poster Awards at 55th Annual Drosophila Research Conference

Study reveals surprising relationships between diet and release of hormones that suppress eating

Renal dysfunction affects NT-proBNP predictive thresholds in pulmonary hypertension

PARADIGM-HF trial of LCZ696 for chronic heart failure stopped early for benefit

Urine test can indicate presence of venous thromboembolism in patients at risks for clots

Study: E-cigarettes appear to increase virulence of drug- resistant and life-threatening bacteria

Nanogel heals burn wounds faster

Researchers show how cone snails venom inhibits neuronal calcium channels to reduce neuropathic pain

Anti-depressants could slow onset of Alzheimer's disease

Investigators find effective treatment for life-threatening angioedema attacks in ED

Novozymes Biopharma, ThioLogics to collaborate on drug-albumin conjugation platform

Scientists discover novel protein fragments that may protect against Alzheimer's disease

Editorial Focus eBook - Peptides and Oligonucleotides (2nd edition) eBook

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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