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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

Neurons involved in creating negative emotional states and chronic stress identified

Researchers at Karolinska Institutet in Sweden have identified a group of nerve cells in the mouse brain that are involved in creating negative emotional states and chronic stress. The

22 Jun 2023

Single mutation of the hepatitis E virus stands in the way of sofosbuvir drug's effectiveness

A single mutation stands in the way of a drug's effectiveness. Understanding it helps find new therapeutic approaches.

21 Jun 2023

Alternative splicing in neurodegenerative disease and the promise of RNA-based therapeutic strategies

Alternative splicing, a clever way a cell generates many different variations of messenger RNAs - single-stranded RNAs involved in protein synthesis - and proteins from the same stretch of DNA, plays an important role in molecular biology.

21 Jun 2023

Research explains mechanisms behind anti-viral protection in hemochorial placentas

Give credit to your dad's gene for keeping you safe during those long months in your mother's womb.

20 Jun 2023

Intranasal delivery of CRISPR/Cas9 therapeutics may help treat chronic anxiety

A study in mice reports a CRISPR/Cas9 gene-editing delivery system, capable of bypassing the blood-brain-barrier and modulating neuronal receptor pathways, to treat chronic anxiety.

20 Jun 2023

The contribution of transcription factor ROB1 to the pathophysiology of C. albicans-induced candidal infections

Researchers evaluated the function of the zinc finger transcription factor ROB1 and its two phenotypically distinct alleles in the pathogenesis of Candida albicans infections.

20 Jun 2023

Battle against RSV: Computational design paves way for new polyvalent vaccine

Research focuses on the design of a multi-epitope polyvalent vaccine against Human Respiratory Syncytial Virus (RSV), a leading cause of lower respiratory tract infections. The study utilizes computational methods and immunoinformatics tools to predict potential vaccine candidates and their interactions with Toll-like receptors (TLRs).

19 Jun 2023

Investigating the incidences and risks of rotavirus-associated extraintestinal complications in hospitalized children under 5

Researchers studied extraintestinal complications of rotavirus infections in children below the age of five.

16 Jun 2023

MGI partners with Xpress Genomics to advance deep single-cell RNA-sequencing technologies

MGI, a company committed to building core tools and technology to lead life science, announced the signing of a licensing agreement with Xpress Genomics, a leading Stockholm-based company specializing in automated and scalable RNA-sequencing strategies.

From MGI 16 Jun 2023

MGI reveals latest updates at ESHG conference in Glasgow

MGI Tech Co., Ltd. ("MGI"), a company committed to building core tools and technology to lead life science, held a Corporate Satellite Meeting and revealed significant local partnerships at the ESHG Conference in Glasgow.

From MGI 16 Jun 2023

A framework of the recombination pathway for coronaviruses

Researchers explored the different aspects of the coronavirus recombination pathway.

16 Jun 2023

Aging impacts cellular composition across the whole fly: Study

As the body ages, organ function progressively declines and the risk for a wide range of diseases, including cardiovascular disease, cancer and neurodegenerative diseases, increases. Understanding how the body ages is an intense area of research as it will potentially illuminate ways to promote healthy aging.

16 Jun 2023

COVID-19 susceptibility mechanism discovered using a newly created tool

Researchers have discovered a mechanism for COVID-19 susceptibility using a newly created tool. The tool, GASPACHO, captures dynamic changes in gene expression along the innate immune response, allowing researchers to identify genes and molecular pathways associated with disease risk that have previously been too complex to detect or interpret.

15 Jun 2023

Insilico announces new multimodal transformer-based aging clock for processing diverse data sets

Clinical stage generative artificial intelligence (AI)-driven drug discovery company Insilico Medicine ("Insilico") has announced a new multimodal transformer-based aging clock that is capable of processing diverse data sets and providing insights into biomarkers for aging, mapping them to genes relevant to both aging and disease, and discovering new therapeutic targets designed to slow or reverse both aging and aging-related diseases.

15 Jun 2023

New findings expand the genotypic spectrum of NPRL3-associated focal epilepsy

Science China Life Sciences magazine recently reported on the research results of Tang Beisha's team from Xiangya Hospital of Central South University, Liu Jing Yu's team from the Institute of Neurology of the Chinese Academy of Sciences, and Zhang Luoying's team from Huazhong University of Science and Technology, including Du Shiyue, Zeng Sheng, and Song Li. Epilepsy has a complex etiology with 80% owing a genetic basis.

15 Jun 2023

A new weapon against COVID: RBD-62 protein shows promising results in preventing severe disease

Researchers used aerosolized receptor binding domain (RBD)-62 with 1,000-fold enhanced binding affinity.

15 Jun 2023

Molecular insights into long COVID: serum proteome reveals dominant signaling pathways

Researchers examined the serum proteome of unvaccinated adults who had PASC.

15 Jun 2023

Scientists identify major mechanism behind the transition between chronic and acute bacterial infections

People with weakened immune systems are at constant risk of infection. Pseudomonas aeruginosa, a common environmental bacterium, can colonize different body parts, such as the lungs, leading to persistent, chronic infections that can last a lifetime – a common occurrence in people with cystic fibrosis.

14 Jun 2023

Psychedelics reopen ‘critical periods’ for social reward learning, mice study shows

Neuroscientists have long searched for ways to reopen "critical periods" in the brain, when mammals are more sensitive to signals from their surroundings that can influence periods of brain development.

14 Jun 2023

An analysis of the differential effect and the impact of SARS-CoV-2 infection on semen quality

Study analyzed the impact of SARS-CoV-2 infection on semen quality.

14 Jun 2023

RNA News and Research

Further Reading

Neurons involved in creating negative emotional states and chronic stress identified

Single mutation of the hepatitis E virus stands in the way of sofosbuvir drug's effectiveness

Alternative splicing in neurodegenerative disease and the promise of RNA-based therapeutic strategies

Research explains mechanisms behind anti-viral protection in hemochorial placentas

Intranasal delivery of CRISPR/Cas9 therapeutics may help treat chronic anxiety

The contribution of transcription factor ROB1 to the pathophysiology of C. albicans-induced candidal infections

Battle against RSV: Computational design paves way for new polyvalent vaccine

Investigating the incidences and risks of rotavirus-associated extraintestinal complications in hospitalized children under 5

MGI partners with Xpress Genomics to advance deep single-cell RNA-sequencing technologies

MGI reveals latest updates at ESHG conference in Glasgow

A framework of the recombination pathway for coronaviruses

Aging impacts cellular composition across the whole fly: Study

COVID-19 susceptibility mechanism discovered using a newly created tool

Insilico announces new multimodal transformer-based aging clock for processing diverse data sets

New findings expand the genotypic spectrum of NPRL3-associated focal epilepsy

A new weapon against COVID: RBD-62 protein shows promising results in preventing severe disease

Molecular insights into long COVID: serum proteome reveals dominant signaling pathways

Scientists identify major mechanism behind the transition between chronic and acute bacterial infections

Psychedelics reopen ‘critical periods’ for social reward learning, mice study shows

An analysis of the differential effect and the impact of SARS-CoV-2 infection on semen quality

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