DNA News and Research

RSS

DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Researchers identify key genetic variants linked to ALS recovery

Though exceedingly rare, some people diagnosed with amyotrophic lateral sclerosis (ALS) partially or fully recover from the lethal neurodegenerative disease.

30 Jul 2024

Targeting oncogenic transcription factors to develop potential new cancer treatments

A new study from the University of Michigan Health Rogel Cancer Center furthers research that suggests the potential of developing new cancer treatments to target oncogenic transcription factors by indirectly affecting their ability to access enhancer DNA in chromatin.

30 Jul 2024

Epigenetic reprogramming and hypothalamic changes in metabolic syndrome

Metabolic syndrome (MetS) is a multifaceted disorder that impacts approximately 20–25% of the global population.

30 Jul 2024

Study finds higher levels of lncRNAs in the testes than previously estimated

Researchers at the University of Toronto have mapped the spatial distribution of around 700 long non-coding RNAs, otherwise known as lncRNAs, in the testes.

30 Jul 2024

ACE technology enhances single-cell protein detection with advanced signal amplification

Since the 1950s, researchers have used a famous method invented by Wallace Coulter known as "flow cytometry" to characterize different types of immune cells in research studies and in blood samples from human individuals.

30 Jul 2024

DNA repair gene mutations predict bladder cancer response to neoadjuvant chemotherapy

An analysis of pre-treatment tumor specimens from 105 patients with localized muscle-invasive bladder cancer found that the presence of a mutation in any one of three genes, all known to be involved in DNA damage repair, was associated with complete pathologic response to cisplatin-based neoadjuvant chemotherapy as measured by pathological downstaging at the time of bladder surgery.

29 Jul 2024

FDA-approved iron-chelating drug could provide a novel way to attack ovarian tumors

An iron-binding drug that is already approved for treatment of other diseases could provide a novel way to attack ovarian tumors, according to a new study led by Weill Cornell Medicine researchers.

29 Jul 2024

Losing a loved one linked to faster biological aging

Losing someone close, like a family member, can make you age faster, says a new study from Columbia University Mailman School of Public Health and the Butler Columbia Aging Center.

29 Jul 2024

Study finds link between healthy diet with less sugar and younger biological age

Researchers at UC San Francisco have found a link between following a diet that is rich in vitamins and minerals, especially one without much added sugar, and having a younger biological age at the cellular level.

29 Jul 2024

Advancing hepatic cell carcinoma treatment through mitochondrial DNA targeting

Hepatic cell carcinoma (HCC), the fifth most prevalent malignancy worldwide and the fourth leading cause of cancer-related mortality, poses significant therapeutic challenges.

29 Jul 2024

Understanding iron overload in β-thalassemia: Mechanisms, diagnosis, and treatments

β-Thalassemia is a genetic disorder characterized by reduced or absent synthesis of the beta chains of hemoglobin, leading to ineffective erythropoiesis and severe anemia.

29 Jul 2024

Eight-week vegan diet linked to epigenetic age reduction in identical twins

Eating a vegan diet for eight weeks is associated with reductions in biological age estimations based on levels of DNA methylation - a type of chemical modification of DNA (known as an epigenetic modification) that alters gene expression but not DNA itself.

28 Jul 2024

New zwitterionic polyion developed for effective plasmid DNA delivery in muscle cells

Researchers from Tokyo Metropolitan University have created a new drug delivering molecule, a zwitterionic polymer complex that can help get plasmid DNA inside cells when injected into skeletal muscle, a crucial step in the expression of therapeutic RNA and proteins.

28 Jul 2024

Cytomegalovirus in breast milk linked to changes in infant growth and gut microbiome

Research shows human cytomegalovirus (CMV) reactivation in breast milk affects milk composition, infant gut microbiome, and growth, with potential impacts on neonatal health.

28 Jul 2024

Innovative dual-drug strategy for colorectal cancer treatment

A combination of two drugs was capable of suppressing tumors in a non-conventional manner. Instead of inhibiting tumor cell division, as the most widely used medications do, the strategy consisted of hyperactivating oncogenic signaling by these cells to the point where they became stressed.

27 Jul 2024

Cellular competition determines X chromosome usage in female bodies

A new study published in Nature Genetics by the Lymphoid Development Group at the MRC Laboratory of Medical Sciences has reveals that the contribution of cells expressing maternal or paternal X chromosomes can be selectively skewed in different parts of the body. The study leverages human data from the 1000 Genomes Project combined with mouse models of human X chromosome-linked DNA sequence variation to advance our fundamental understanding of development in biologically female individuals who have two X chromosomes.

26 Jul 2024

Alarming spread of H5N1 bird flu in US dairy cattle reveals cross-species transmission dangers

Researchers discovered that the H5N1 avian influenza virus has spilled over into dairy cattle in the US, posing significant cross-species transmission risks. Their multidisciplinary study reveals the virus's evolution and its zoonotic potential, emphasizing the need for heightened biosecurity measures.

25 Jul 2024

DNA News and Research

Further Reading

Researchers identify key genetic variants linked to ALS recovery

Targeting oncogenic transcription factors to develop potential new cancer treatments

Epigenetic reprogramming and hypothalamic changes in metabolic syndrome

Study finds higher levels of lncRNAs in the testes than previously estimated

ACE technology enhances single-cell protein detection with advanced signal amplification

DNA repair gene mutations predict bladder cancer response to neoadjuvant chemotherapy

FDA-approved iron-chelating drug could provide a novel way to attack ovarian tumors

Losing a loved one linked to faster biological aging

Study finds link between healthy diet with less sugar and younger biological age

Advancing hepatic cell carcinoma treatment through mitochondrial DNA targeting

Understanding iron overload in β-thalassemia: Mechanisms, diagnosis, and treatments

Eight-week vegan diet linked to epigenetic age reduction in identical twins

New zwitterionic polyion developed for effective plasmid DNA delivery in muscle cells

Cytomegalovirus in breast milk linked to changes in infant growth and gut microbiome

Innovative dual-drug strategy for colorectal cancer treatment

Cellular competition determines X chromosome usage in female bodies

Alarming spread of H5N1 bird flu in US dairy cattle reveals cross-species transmission dangers

Experimental cancer drug may help clear HIV from infected cells in the brain

Understanding the epigenetic regulation of hepatic stellate cells in NAFLD

Innovative array targets methylation in imprinted genes, simplifies epigenetic research

Understanding the DNA Damage Response in Innate Immunity eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo