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St. Jude researchers show how drug makers can avoid toxicity and resistance

Scientists at St. Jude Children's Research Hospital have demonstrated how drug makers can avoid two key problems: toxicity and resistance.

28 Feb 2023

Five Alarm Bio, Focused on Minimising the Effects of Aging in Humans, Raises Seed Investment

Investors include Cambridge Angels, Meltwind, o2h Ventures, SyndicateRoom, and Angel investors, with support from KPMG Acceleris.

From Five Alarm Bio 28 Feb 2023

Using the origami technique to design RNA nanostructures

Researchers from Aarhus University and Berkeley Laboratory have designed RNA molecules, that folds into nanoscale rectangles, cylinders, and satellites, and have studied their 3D structure and dynamics with advanced nanotechnological methods.

28 Feb 2023

Researchers reveal how early-life stress can disrupt operation of the brain's reward circuit

A new brain connection discovered by University of California, Irvine researchers can explain how early-life stress and adversity trigger disrupted operation of the brain's reward circuit, offering a new therapeutic target for treating mental illness.

27 Feb 2023

Researchers explore potential new target for cancer immunotherapy

A new study posted to the bioRxiv* preprint server, focused on the role of YAP in regulating MHC-I APM expression within tumor cells.

27 Feb 2023

Study findings likely to guide the design of engineered TAPBPR variants with tailored HLA specificity

Researchers at Children's Hospital of Philadelphia (CHOP) have identified variants of a chaperone molecule that optimizes the binding and presentation of foreign antigens across the human population, which could open the door to numerous applications where robust presentation to the immune system is important, including cell therapy and immunization. The findings were published today in Science Advances.

24 Feb 2023

Study analyzes the potential of a natural amino acid as new way to cure COVID-19

After more than two years since its discovery, six million deaths, and half a billion reported cases, there is still no effective cure for COVID-19. Even though vaccines have lowered the impact of outbreaks, patients that contract the disease can only receive supportive care while they wait for their own body to clear the infection.

24 Feb 2023

More frequent cannabis use associated with higher risk of coronary artery disease

People who used marijuana daily were found to be about one-third more likely to develop coronary artery disease (CAD) compared with people who have never used the drug, according to a study presented at the American College of Cardiology's Annual Scientific Session Together With the World Congress of Cardiology.

24 Feb 2023

Oleic acid: Principal component of olive oil responsible for many health-promoting properties

Oleic acid, the principal component of olive oil, has properties that help to prevent cancer and Alzheimer's disease and to lower cholesterol.

23 Feb 2023

Study identifies placental growth factor as a biomarker for vascular cognitive impairment

Measuring a key blood molecule may help doctors diagnose whether or how much impaired blood flow to a patient's brain is contributing to dementia or cognitive problems, according to a new study led by a UCLA Health researcher.

23 Feb 2023

A study of the effects of beta-alanine supplements on soldiers' performance

Researchers review the effects of β-alanine supplementation on soldiers’ performance, cognition, and resilience.

22 Feb 2023

A bitter battle over the ‘orphan drug’ program leaves patients’ pocketbooks at risk

A prescription drug that helps Lore Wilkinson walk and talk despite a rare muscle disease cost her so little for more than a decade that she didn't even use her insurance to pay for it.

22 Feb 2023

Dietary polyphenols may play a role in regulating inflammatory immune responses

PCB2DG, a polyphenol with anti-inflammatory properties, works by targeting and directly interacting with the major glutamine transporter protein, alanine serine cysteine transporter 2 (ASCT2), to inhibit the uptake of glutamine, an important amino acid found in the blood.

22 Feb 2023

Life Sciences Innovator Category Winner 2023

Following a rigorous application process, we are proud to announce that Seda have been selected as the UK Life Sciences Innovator Winner 2023 in the Application, Product & Service Design Category.

From Seda Pharmaceutical Development Services 21 Feb 2023

Researchers provide a framework for unifying and categorizing neurodegenerative diseases based on eight hallmarks

Researchers presented eight hallmarks of neurodegenerative diseases (NDDs), their in vivo biomarkers, and interactions to help categorize NDDs and specify patients within a specific NDD.

21 Feb 2023

First fully human ovarian organoids provide insights about female reproductive health and disease

Despite the fact that we all start out as an egg cell in one of our mother's ovaries, these human reproductive organs are surprisingly under-studied.

21 Feb 2023

Simple blood tests for telomeric protein could provide a valuable screen for certain cancers

Once thought incapable of encoding proteins due to their simple monotonous repetitions of DNA, tiny telomeres at the tips of our chromosomes seem to hold a potent biological function that's potentially relevant to our understanding of cancer and aging.

21 Feb 2023

Molecule News and Research

St. Jude researchers show how drug makers can avoid toxicity and resistance

Five Alarm Bio, Focused on Minimising the Effects of Aging in Humans, Raises Seed Investment

Using the origami technique to design RNA nanostructures

Researchers reveal how early-life stress can disrupt operation of the brain's reward circuit

Researchers explore potential new target for cancer immunotherapy

Study findings likely to guide the design of engineered TAPBPR variants with tailored HLA specificity

Study analyzes the potential of a natural amino acid as new way to cure COVID-19

More frequent cannabis use associated with higher risk of coronary artery disease

Oleic acid: Principal component of olive oil responsible for many health-promoting properties

Study identifies placental growth factor as a biomarker for vascular cognitive impairment

A study of the effects of beta-alanine supplements on soldiers' performance

A bitter battle over the ‘orphan drug’ program leaves patients’ pocketbooks at risk

Dietary polyphenols may play a role in regulating inflammatory immune responses

Life Sciences Innovator Category Winner 2023

Researchers provide a framework for unifying and categorizing neurodegenerative diseases based on eight hallmarks

First fully human ovarian organoids provide insights about female reproductive health and disease

Simple blood tests for telomeric protein could provide a valuable screen for certain cancers

Structure of DREADD designer receptor could pave the way for creating next generation tools

Ketamine appears to hold promise in treating cocaine-use disorders

Activating or deactivating drugs with the help of light

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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