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Novartis, Bristol-Myers Squibb collaborate to examine combination therapies for metastatic colorectal cancer

Novartis today announced it has entered into a clinical research collaboration in which Bristol-Myers Squibb will investigate the safety, tolerability, and efficacy of Mekinist (trametinib) in combination with Opdivo (nivolumab) and Opdivo + Yervoy (ipilimumab) regimen as a potential treatment option for metastatic colorectal cancer in patients with microsatellite stable tumors where the tumors are proficient in mismatch repair (MSS mCRC pMMR).

5 Jun 2017

Study explores effects of androgen deprivation therapy on overall geriatric health

Androgen drives many prostate cancers. But the body uses androgen for muscle growth and maintenance, among other functions.

5 Jun 2017

New genomic sequencing approach could be first step toward blood tests for early cancer detection

In a study of 124 patients with advanced breast, lung, and prostate cancers, a new, high-intensity genomic sequencing approach detected circulating tumor DNA at a high rate.

5 Jun 2017

Single-dose radiotherapy effectively reduces spinal cord compression symptoms

A common complication in people with metastatic cancer, spinal cord compression is a major detriment to quality of life. Radiation treatment is widely used to relieve pain and other symptoms, but there is no standard recommended schedule, and approaches currently vary.

5 Jun 2017

Positive results for AstraZeneca’s PARP inhibitor Lynparza in advanced breast cancer

A new study has shown that AstraZeneca's Lynparza (olaparib) can significantly slow the progress of breast cancer that is caused partially due to mutations of the culprit gene called BRCA. BRCA gene mutations are responsible for around 3% of all breast cancers. These cases of the disease that have a basis in the gene are notoriously difficult to treat and women who are tested positive for this gene may even opt for removal of their breasts before even the cancer strikes. Noted actress Angelina Jolie went for a similar prophylactic mastectomy.

5 Jun 2017

Standard therapy plus abiraterone lowers relative risk of death in men with advanced prostate cancer

A clinical trial of nearly 2,000 men shows that adding abiraterone acetate (Zytiga) to a standard initial treatment regimen for high-risk, advanced prostate cancer lowers the relative risk of death by 37%.

5 Jun 2017

Genetic sequencing could help direct treatment for 72% of advanced cancer patients

A new analysis finds that nearly three-quarters of 500 patients with advanced cancer could be referred to a potential targeted treatment based on the results of a comprehensive analysis of their tumor's genetic landscape.

2 Jun 2017

Clinical trial uses small molecule to treat men with incurable prostate cancer

NewYork-Presbyterian and Weill Cornell Medicine have begun the first clinical trial in the United States that uses a small molecule to treat men with progressive prostate cancer that has spread beyond the prostate and is no longer responding to hormonal therapy.

31 May 2017

Researchers develop new plasmonic sensor that improves early detection of cancer biomarkers

A new plasmonic sensor developed by researchers at the University of Illinois at Urbana-Champaign will serve as a reliable early detection of biomarkers for many forms of cancer and eventually other diseases.

31 May 2017

Study finds opioid dependence and overdose rates after urologic surgery

About 1 in 1,111 patients who undergo urologic surgery for conditions such as prostate cancer and kidney stones experience opioid dependence or overdose (ODO), a Loyola Medicine study has found.

30 May 2017

Raising age limit for routine genetic testing in colorectal cancer could identify more cases of Lynch syndrome

Raising the age limit for routine genetic testing in colorectal cancer could identify more cases of families affected by Lynch syndrome, a condition that accounts for around 5% of all colon cancers, according to new research to be presented at the annual conference of the European Society of Human Genetics today (Monday).

29 May 2017

Prolaris becomes first genetic test to receive Medicare coverage for favorable intermediate and low-risk prostate cancer

Myriad Genetics, Inc., a leader in molecular diagnostics and personalized medicine, today announced that Palmetto GBA, a Medicare Administrative Contractor that assesses molecular diagnostic technologies, has issued a positive final Local Coverage Determination to expand Medicare coverage of the Prolaris test.

29 May 2017

FDA approves expanded use of Zykadia for first-line treatment of ALK-positive metastatic NSCLC

Novartis today announced the US Food and Drug Administration approved the expanded use of Zykadia (ceritinib) to include the first-line treatment of patients with metastatic non-small cell lung cancer (NSCLC) whose tumors are anaplastic lymphoma kinase (ALK)-positive, as detected by an FDA-approved test.

27 May 2017

Researchers use chemical array to find malignant cells within melanoma tumor

Melanoma is a particularly difficult cancer to treat once it has metastasized, spreading throughout the body. University of Illinois researchers are using chemistry to find the deadly, elusive malignant cells within a melanoma tumor that hold the potential to spread.

26 May 2017

Lung cancer diagnosis may put patients at greatest risk of suicide, study finds

A lung cancer diagnosis appears to put patients at the greatest risk of suicide when compared to the most common types of non-skin cancers, according to new research presented at the ATS 2017 International Conference.

23 May 2017

FDA grants accelerated approval to cancer treatment based on common biomarker

The U.S. Food and Drug Administration today granted accelerated approval to a treatment for patients whose cancers have a specific genetic feature (biomarker).

23 May 2017

Physically active lifestyle, limiting alcohol could help lower breast cancer risk

Drinking just one glass of wine or other alcoholic drink a day increases breast cancer risk, finds a major new report by the American Institute for Cancer Research and the World Cancer Research Fund.

23 May 2017

Study shows new promise in the fight against pancreatic cancer

New research from the Keck School of Medicine of the University of Southern California shows new promise in the fight against one of the most lethal forms of cancer.

23 May 2017

Study: Educational session effective at reducing distress in prostate cancer patients and female partners

In a recent study, an educational session helped alleviate distress equally in both patients with prostate cancer and their partners.

19 May 2017

DNAe’s article on semiconductor DNA analysis technology placed in Scientific Reports’ top 100 read list for 2016

DNA Electronics, the inventor of semiconductor DNA sequencing technology and developer of a new, revolutionary blood-to-result test for bloodstream infections, announces that an article on research utilizing the Company’s patented semiconductor DNA analysis technology has achieved recognition as one of the top 100 read articles for 2016 in Scientific Reports, a peer reviewed journal from the publishers of Nature.

19 May 2017

Prostate News and Research

Novartis, Bristol-Myers Squibb collaborate to examine combination therapies for metastatic colorectal cancer

Study explores effects of androgen deprivation therapy on overall geriatric health

New genomic sequencing approach could be first step toward blood tests for early cancer detection

Single-dose radiotherapy effectively reduces spinal cord compression symptoms

Positive results for AstraZeneca’s PARP inhibitor Lynparza in advanced breast cancer

Standard therapy plus abiraterone lowers relative risk of death in men with advanced prostate cancer

Genetic sequencing could help direct treatment for 72% of advanced cancer patients

Clinical trial uses small molecule to treat men with incurable prostate cancer

Researchers develop new plasmonic sensor that improves early detection of cancer biomarkers

Study finds opioid dependence and overdose rates after urologic surgery

Raising age limit for routine genetic testing in colorectal cancer could identify more cases of Lynch syndrome

Prolaris becomes first genetic test to receive Medicare coverage for favorable intermediate and low-risk prostate cancer

FDA approves expanded use of Zykadia for first-line treatment of ALK-positive metastatic NSCLC

Researchers use chemical array to find malignant cells within melanoma tumor

Lung cancer diagnosis may put patients at greatest risk of suicide, study finds

FDA grants accelerated approval to cancer treatment based on common biomarker

Physically active lifestyle, limiting alcohol could help lower breast cancer risk

Study shows new promise in the fight against pancreatic cancer

Study: Educational session effective at reducing distress in prostate cancer patients and female partners

DNAe’s article on semiconductor DNA analysis technology placed in Scientific Reports’ top 100 read list for 2016

What to know about prostate cancer eBook

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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