immunity News and Research

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High ammonia levels lead to fewer T cells and immunotherapy resistance in colorectal cancer

High levels of ammonia in tumors lead to fewer T cells and immunotherapy resistance in mouse models of colorectal cancer, new findings from the University of Michigan Rogel Cancer Center revealed.

23 Dec 2022

Researchers present a new strategy for self-adjuvanting vaccine development

This new article publication from Acta Pharmaceutica Sinica B, discusses a fully synthetic Tn-based three-component cancer vaccine using covalently linked TLR4 ligand MPLA and iNKT cell agonist KRN-7000 as built-in adjuvant effectively protects mice from tumor development.

23 Dec 2022

Scientists study OAS–RNase L errors and COVID-19-associated multisystem inflammatory syndrome in children

Researchers assessed the inborn abnormalities of 2′-5′-oligoadenylate synthetase (OAS)-ribonuclease L (RNASEL) noted in coronavirus disease 2019 (COVID-19)-associated multisystem inflammatory syndrome in children (MIS-C).

23 Dec 2022

People eligible for free winter vaccines urged to come forward over the Christmas holiday

All those eligible for their free winter vaccines are being urged to come forward as soon as possible for their free jabs over the Christmas holiday, as hospitalizations for flu and Covid continue to rise.

23 Dec 2022

Exploring plasma and nasal antibody responses to SARS-CoV-2 infection and vaccination

Researchers evaluated plasma and nasal antibody titers responses induced by natural severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and coronavirus disease 2019 (COVID-19) vaccinations among United Kingdom (UK) residents.

23 Dec 2022

Novel mRNA-lipid nanoparticle vaccine encoding four mpox virus surface proteins generates robust immune responses against orthopoxviruses

Researchers described a messenger ribonucleic acid (mRNA)-lipid nanoparticle monkeypox vaccine encoding four conserved monkeypox virus surface proteins which induced monkeypox virus-specific immunity and elicited heterologous protection when challenged with lethal vaccinia virus.

23 Dec 2022

Hybrid immunity from mRNA vaccines and breakthrough Omicron infections induces stronger immune responses against Omicron BQ.1.1

Researchers evaluated plasma samples from individuals vaccinated with a fourth booster dose of mono- or bivalent mRNA SARS-CoV-2 vaccine to evaluate the recognition and neutralization capacity against the ancestral (D614G) strain and the Omicron BQ.1.1 subvariant.

23 Dec 2022

Beta-containing COVID-19 booster vaccine found to cross-neutralize variants in non-human primates

A new paper presents preliminary evidence that a new vaccine candidate, designed to boost immunity in already immunized individuals, and containing the adjuvanted Beta spike variant protein antigen, can induce a potent cross-neutralizing antibody response in non-human primate models that is detectable for up to three months.

23 Dec 2022

UC San Diego researchers rewrite the textbook on gene regulation

A fundamental principle of molecular biology governs how proteins are made within the cell, which happens in two stages called transcription and translation.

22 Dec 2022

COVID-19 vaccination protects people with B cell lymphoma and multiple myeloma

A recent Nature Cancer study documented that individuals with B cell lymphomas (LY) and multiple myeloma (MM) developed potent infection neutralization capabilities against several SARS-CoV-2 variants of concern (VoCs).

22 Dec 2022

Bivalent mRNA vaccine is moderately effective in preventing COVID-19

Researchers assesses the real-world efficacy of the novel bivalent COVID-19 vaccine.

22 Dec 2022

Using the gut microbiome to understand and treat respiratory diseases

Researchers review the role of the gut microbiome in certain respiratory diseases.

22 Dec 2022

Simple laser irradiation speeds up the detection of very small amounts of proteins

Protein detection based on antigen–antibody reaction is vital in early diagnosis of a wide range of diseases. How to effectively detect proteins, however, has frequently bedeviled researchers.

22 Dec 2022

Research sheds light on how mRNA boosters affect the durability of antibodies to COVID-19

New research from the University of Virginia School of Medicine speaks to the benefits of a COVID-19 booster.

22 Dec 2022

Characterization of anti-orthopoxvirus antibody response in general population and gay men

Scientists have recently estimated and compared anti-mpox and anti-vaccinia antibodies in gay men and the general population.

22 Dec 2022

Virologists measure the level of herd immunity to hepatitis A virus

RUDN University virologists measured the level of herd immunity to hepatitis A virus in different regions of Russia.

22 Dec 2022

T-cell immunity remains effective against SARS-CoV-2 Omicron subvariants

Omicron subvariants effectively escape B-cell immune responses by modifying neutralizing antibody epitopes.

21 Dec 2022

Study reveals why human lymph nodes lose their function with age

A new study from researchers at Uppsala University presents novel findings on why human lymph nodes lose their function with age and the consequences for the effectiveness of our immune system. The article has been published in The Journal of Pathology.

21 Dec 2022

Comprehensive lung cell atlas offers insights into an unexpected immune niche in the airways

The most comprehensive lung cell atlas to date, from the Wellcome Sanger Institute and collaborators, has revealed 11 new lung cell types and offers detailed insight into an immune process involved in fighting lung infections.

21 Dec 2022

Brief roundup of research done by experts at UCLA Health

Below is a brief roundup of news and story ideas from the experts at UCLA Health.

21 Dec 2022

immunity News and Research

High ammonia levels lead to fewer T cells and immunotherapy resistance in colorectal cancer

Researchers present a new strategy for self-adjuvanting vaccine development

Scientists study OAS–RNase L errors and COVID-19-associated multisystem inflammatory syndrome in children

People eligible for free winter vaccines urged to come forward over the Christmas holiday

Exploring plasma and nasal antibody responses to SARS-CoV-2 infection and vaccination

Novel mRNA-lipid nanoparticle vaccine encoding four mpox virus surface proteins generates robust immune responses against orthopoxviruses

Hybrid immunity from mRNA vaccines and breakthrough Omicron infections induces stronger immune responses against Omicron BQ.1.1

Beta-containing COVID-19 booster vaccine found to cross-neutralize variants in non-human primates

UC San Diego researchers rewrite the textbook on gene regulation

COVID-19 vaccination protects people with B cell lymphoma and multiple myeloma

Bivalent mRNA vaccine is moderately effective in preventing COVID-19

Using the gut microbiome to understand and treat respiratory diseases

Simple laser irradiation speeds up the detection of very small amounts of proteins

Research sheds light on how mRNA boosters affect the durability of antibodies to COVID-19

Characterization of anti-orthopoxvirus antibody response in general population and gay men

Virologists measure the level of herd immunity to hepatitis A virus

T-cell immunity remains effective against SARS-CoV-2 Omicron subvariants

Study reveals why human lymph nodes lose their function with age

Comprehensive lung cell atlas offers insights into an unexpected immune niche in the airways

Brief roundup of research done by experts at UCLA Health

Exploring Strategies for Targeting Kinases in Innate Immunity eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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