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Case Western Reserve researchers find potential game-changer for triple-negative breast cancer

Researchers at Case Western Reserve University combined finely crafted nanoparticles with one of nature's potent disrupters to prevent the spread of triple-negative breast cancer in mouse models.

13 May 2015

Scientists discover way to regrow bone tissue using proteins produced by stem cells

Scientists have discovered a way to regrow bone tissue using the protein signals produced by stem cells. This technology could help treat victims who have experienced major trauma to a limb, like soldiers wounded in combat or casualties of a natural disaster. The new method improves on older therapies by providing a sustainable source for fresh tissue and reducing the risk of tumor formation that can arise with stem cell transplants.

13 May 2015

Catatonia may cause regression in Down syndrome patients

Down syndrome, the most common chromosomal disorder in America, can be complicated by significant deterioration in movement, speech and functioning in some adolescents and young adults. Physicians previously attributed this regression to depression or early-onset Alzheimer's, and it has not responded to treatments.

13 May 2015

Researchers develop new tool to identify common genetic anomalies in cancer

Researchers from the University of Michigan Comprehensive Cancer Center and Thermo Fisher Scientific have developed and tested a new tool that searches for the most common genetic anomalies seen in cancer. The assay demonstrates the ability to make gene sequencing easier over a large volume of samples.

13 May 2015

Research paves way for development of individualized immunotherapy for treating cancer

Mainz-based researchers have made significant advances with regard to the development of individualized immunotherapy strategies for treating cancer. They have managed to identify the relevant genetic changes or mutations associated with various types of cancer and have determined their individual blueprints.

13 May 2015

Orthocell’s Ortho-ATI therapy improves clinical outcomes in patients with tennis elbow degeneration

Regenerative medicine company Orthocell Limited is pleased to announce positive 3-5 year data from a study of its tendon cell treatment for tennis elbow has been presented at the International Cartilage Repair Society annual scientific meeting.

13 May 2015

Managing cancer at work: Johns Hopkins launches new service for all employees

Johns Hopkins Medicine has created and launched Managing Cancer at Work, a new and novel health benefit program offered free of charge for its more than 42,000 combined full-time equivalent employees.

12 May 2015

Two physicians examine heart disease through a literary lens

Heart disease has topped mortality charts as the No. 1 killer of men and women for many decades, but a novel analysis of American literary fiction by two physicians finds the disorder’s presence in great novels has remained relatively modest.

12 May 2015

European Investment Bank supports Bavarian Nordic’s development of Ebola and cancer vaccines

The European Investment Bank (EIB), the world’s largest multilateral bank, today reaffirmed its firm commitment to respond to the Ebola pandemic. The Bank has provided a EUR 50 million loan to Bavarian Nordic, an international biopharmaceutical company, for accelerated development of an Ebola vaccine with long-term efficacy. The financing is also backing research into vaccines for treating other infectious diseases and multiple cancer indications.

12 May 2015

Childhood cancer survivors more likely to be obese than healthy peers

Childhood cancer survivors - especially those whose treatment included brain irradiation or chemotherapy with glucocorticoids - are 14 percent more likely to be obese than their healthy peers.

12 May 2015

Powerheart G5 AED era arrives in the U.S. and Canada

Cardiac Science, an Opto Circuits group company and a global leader in AEDs, is proud to announce today that the Powerheart G5 AED era has arrived in the United States and Canada, representing both a technological milestone in the AED industry and the company's latest tool in fighting the world's No. 1 killer: sudden cardiac arrest (SCA).

12 May 2015

Researchers identify three genes involved in choroid plexus carcinoma

Researchers have identified three genes that play a pivotal role in the brain tumor choroid plexus carcinoma (CPC), a discovery that lays the groundwork for more effective treatment of this rare, often fatal cancer. St. Jude Children's Research Hospital scientists led the study, which appears today in the journal Cancer Cell.

12 May 2015

MD Anderson researchers discover link between telomere degeneration and MDS

A study revealing fresh insight about chromosome "tails" called telomeres may provide scientists with a new way to look at developing treatments or even preventing a group of blood cell disorders known as myelodysplastic syndromes (MDS).

12 May 2015

Study: Disrupting cancer pathway could extend benefits of new immunity-boosting drugs

Understanding how to overrule a signaling pathway that can cause treatments to fail in metastatic melanoma patients should help physicians extend the benefits of recently approved immunity-boosting drugs known as checkpoint inhibitors to more patients.

12 May 2015

Leicester research team identifies potential new targets for cancer treatments

An international consortium of scientists led by a group from the University of Leicester has announced a new advance in understanding the mechanisms of cancer and how to target it more effectively with new treatments...

12 May 2015

Going to the dentist just got a little less scary for U.S. children with autism

Going to the dentist might have just gotten a little less scary for the estimated 1 in 68 U.S. children with autism spectrum disorder as well as children with dental anxiety, thanks to new research from USC.

12 May 2015

Experimental gene therapy holds promise against metastatic prostate cancer

Even with the best available treatments, the median survival of patients with metastatic, hormone-refractory prostate cancer is only two to three years. Driven by the need for more effective therapies for these patients, researchers at VCU Massey Cancer Center and the VCU Institute of Molecular Medicine have developed a unique approach that uses microscopic gas bubbles to deliver directly to the cancer a viral gene therapy in combination with an experimental drug that targets a specific gene driving the cancer's growth.

12 May 2015

Study highlights potential new targets for development of novel cancer therapy

12 May 2015

Dana-Farber/Boston Children's joins immunotherapy clinical trial for children with ALL

Dana-Farber/Boston Children's Cancer and Blood Disorders Center has joined a clinical trial of immunotherapy for children with relapsed or treatment-resistant acute lymphoblastic leukemia (ALL). Led by Memorial Sloan Kettering Cancer Center, the trial is one of several nationally that are evaluating cancer immunotherapy, a treatment approach -- hailed by Science magazine as their Breakthrough of the Year in 2013 -- that triggers a patient's immune system to attack his or her cancer cells.

11 May 2015

Overview of Blueprint Medicines' kinase drug discovery strategy published in JCI

Blueprint Medicines today announced that the Journal of Clinical Investigation published an overview of the Company's kinase drug discovery and development strategy. The publication underscores Blueprint Medicines' focus on identifying novel genomically defined disease drivers and the use of novel chemistry from its proprietary compound library to craft highly selective kinase inhibitors for new and difficult-to-drug kinase targets.

11 May 2015

Therapy News and Research

Case Western Reserve researchers find potential game-changer for triple-negative breast cancer

Scientists discover way to regrow bone tissue using proteins produced by stem cells

Catatonia may cause regression in Down syndrome patients

Researchers develop new tool to identify common genetic anomalies in cancer

Research paves way for development of individualized immunotherapy for treating cancer

Orthocell’s Ortho-ATI therapy improves clinical outcomes in patients with tennis elbow degeneration

Managing cancer at work: Johns Hopkins launches new service for all employees

Two physicians examine heart disease through a literary lens

European Investment Bank supports Bavarian Nordic’s development of Ebola and cancer vaccines

Childhood cancer survivors more likely to be obese than healthy peers

Powerheart G5 AED era arrives in the U.S. and Canada

Researchers identify three genes involved in choroid plexus carcinoma

MD Anderson researchers discover link between telomere degeneration and MDS

Study: Disrupting cancer pathway could extend benefits of new immunity-boosting drugs

Leicester research team identifies potential new targets for cancer treatments

Going to the dentist just got a little less scary for U.S. children with autism

Experimental gene therapy holds promise against metastatic prostate cancer

Study highlights potential new targets for development of novel cancer therapy

Dana-Farber/Boston Children's joins immunotherapy clinical trial for children with ALL

Overview of Blueprint Medicines' kinase drug discovery strategy published in JCI

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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