Immune Response News and Research

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Key protein α-synuclein linked to inflammation and Parkinson's disease

Currently, there are no disease modifying therapies for Parkinson's disease that can change the progression of the disease. An international team of scientists led by faculty at the University of Colorado Anschutz Medical Campus is hoping to change that.

30 Jun 2022

Study shows long COVID remodeling of T cell dynamics is dependent on SARS-CoV-2 severity

A new study found that the post-COVID-19 functional remodeling of T cells occurs in two steps and confers different convalescent immune states, six months after SARS-CoV-2 infection.

30 Jun 2022

How to develop an "all-variant" COVID vaccine

In a recent study published in Nature Immunology, researchers summarized their observations of humoral immune responses elicited in severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infected people. Additionally, they discussed all the types of SARS-CoV-2 infection- and vaccine-induced neutralizing antibodies (nAbs).

30 Jun 2022

Casirivimab/imdevimab improve outcomes in early COVID-19

A new Viruses study determines the effect of casirivimab/imdevimab on IFN-1 and cytokines during SARS-CoV-2 infection.

29 Jun 2022

COVID-19 pandemic linked to lower antibodies in breastmilk

New research describes the results of a study measuring such protection and exploring the effects of waning antibody levels on infant susceptibility to respiratory pathogens.

29 Jun 2022

Memory B cells can be localized in the lungs, research shows

How can we increase the efficacy of vaccines used to protect against viral respiratory diseases such as influenza and COVID-19? Scientists from Inserm, CNRS and Aix-Marseille Université at the Center of Immunology Marseille-Luminy are opening up new prospects in the field, with the triggering of memory B cells directly in the lungs looking to be a promising avenue.

28 Jun 2022

Study explores antibody responses following three COVID vaccine doses in kidney transplant recipients

In a recent study posted to the medRxiv* pre-print server, Canadian researchers evaluated antibody responses in kidney transplant recipients (KTRs) before and one and three months after receiving the third dose of a messenger ribonucleic acid (mRNA)-based coronavirus disease 2019 (COVID-19) vaccine.

28 Jun 2022

Phase 1 clinical trial of new influenza vaccine begins at NIH Clinical Center in Bethesda

A Phase 1 clinical trial of a novel influenza vaccine has begun inoculating healthy adult volunteers at the National Institutes of Health Clinical Center in Bethesda, Maryland.

28 Jun 2022

Scientists conduct meta-analysis of the impact of SARS-CoV-2 on sperm parameters

Scientists conducted a meta-analysis to study the impacts of COVID-19 on the male reproductive system.

27 Jun 2022

Breakthrough infection with pre-Omicron variant induces cross-neutralizing activity against Omicron

Researchers evaluated the neutralizing ability of sera from COVID-19 patients.

27 Jun 2022

A full model of the SARS-CoV-2 spike protein for studying its atomic-level dynamics by multiple microsecond simulations

Researchers constructed a full-length SARS-CoV-2 spike structure in its membrane-bound state to study functionally relevant aspects of its global conformational dynamics.

27 Jun 2022

C-reactive protein levels predict ED risk

A recent meta-analysis aimed to describe the relationship between C-reactive protein levels and erectile dysfunction.

27 Jun 2022

Antibody profiles of internal viral proteins predict severe COVID-19 outcomes

Most research on immunity to the SARS-CoV-2 virus and COVID-19 vaccine development has focused on antibody responses to the spike protein and other viral surface proteins.

24 Jun 2022

Inhibiting pore formation in cells may facilitate prevention, treatment of NASH-associated liver cancer

Need another reason to think twice before ordering that extra helping of fries? It could lead to a higher risk of developing liver cancer.

24 Jun 2022

Overlap in pro-inflammatory genes and pathways between COVID-19 and MIS-C

In a recent study posted to the medRxiv* pre-print server, researchers in the United States characterized differential host immune responses in acute coronavirus disease 2019 (COVID-19) and multisystem inflammatory syndrome in children (MIS-C) to inform future development of novel biomarkers for both diseases.

23 Jun 2022

Researchers continue a national study to evaluate COVID-19 vaccination safety pre-and post-delivery

With the SARS-CoV-2 pandemic ongoing, researchers at University of California San Diego School of Medicine, in collaboration with the American Academy of Allergy Asthma and Immunology, will continue a national study to evaluate the safety of COVID-19 vaccinations during pregnancy, and monitor immune response for mother and baby following vaccinations.

23 Jun 2022

Listeria-based booster vaccine strategy offers improved protection against recurrent colorectal cancer

Colorectal, pancreatic, esophageal and stomach cancers - some of the deadliest kinds of cancer - have high recurrence rates where the cancer comes back even after successful surgery or radiation treatment.

23 Jun 2022

The duration of protection conferred by a previous SARS-CoV-2 infection amongst children and adolescents

Researchers evaluated the immunity dynamics following infection with SARS-CoV-2 in children and adolescents.

23 Jun 2022

SARS-CoV-2 evades natural killer cell cytotoxic responses

In a recent study posted to the bioRxiv* preprint server, researchers at Stanford University School of Medicine revealed the mechanism via severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) escapes natural killer (NK) cell cytotoxic reactions.

22 Jun 2022

Preclinical study unlocks the promise of CAR T-cell therapy for treatment of solid tumors

Scientists at St. Jude Children's Research Hospital identified a molecular mechanism that in a preclinical study unlocked the promise of CAR T–cell therapy for treatment of solid tumors.

22 Jun 2022

Immune Response News and Research

Key protein α-synuclein linked to inflammation and Parkinson's disease

Study shows long COVID remodeling of T cell dynamics is dependent on SARS-CoV-2 severity

How to develop an "all-variant" COVID vaccine

Casirivimab/imdevimab improve outcomes in early COVID-19

COVID-19 pandemic linked to lower antibodies in breastmilk

Memory B cells can be localized in the lungs, research shows

Study explores antibody responses following three COVID vaccine doses in kidney transplant recipients

Phase 1 clinical trial of new influenza vaccine begins at NIH Clinical Center in Bethesda

Scientists conduct meta-analysis of the impact of SARS-CoV-2 on sperm parameters

Breakthrough infection with pre-Omicron variant induces cross-neutralizing activity against Omicron

A full model of the SARS-CoV-2 spike protein for studying its atomic-level dynamics by multiple microsecond simulations

C-reactive protein levels predict ED risk

Antibody profiles of internal viral proteins predict severe COVID-19 outcomes

Inhibiting pore formation in cells may facilitate prevention, treatment of NASH-associated liver cancer

Overlap in pro-inflammatory genes and pathways between COVID-19 and MIS-C

Researchers continue a national study to evaluate COVID-19 vaccination safety pre-and post-delivery

Listeria-based booster vaccine strategy offers improved protection against recurrent colorectal cancer

The duration of protection conferred by a previous SARS-CoV-2 infection amongst children and adolescents

SARS-CoV-2 evades natural killer cell cytotoxic responses

Preclinical study unlocks the promise of CAR T-cell therapy for treatment of solid tumors

Understanding the DNA Damage Response in Innate Immunity eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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