Immune System News and Research

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Discovery of a gene that drives anthrax bacteria's toxic effects

A study in Cell reports the discovery of a gene that drives anthrax bacteria's toxic effects. The gene could offer a potential new target for countermeasures against the lethal toxin, according to the researchers.

28 Mar 2006

RNAi-based inhibitors for created for nearly every human and mouse gene - available to all genetic researchers

An international public-private research team led by scientists at the Broad Institute of MIT and Harvard announced today the construction and availability of an extensive library of molecular reagents to silence most human and mouse genes.

28 Mar 2006

Procedure cures some diabetic mice, but not in the way previously reported

Researchers attempting to reproduce a controversial 2003 mouse experiment suggestive of a cure for type 1 diabetes have found evidence that the experimental procedure does eliminate diabetic symptoms in a small fraction of the mice exposed to it.

28 Mar 2006

Researchers find compound 10 times more effective than isoniazid, the leading anti-tuberculosis drug

Researchers at the Albert Einstein College of Medicine of Yeshiva University have synthesized chemicals that are up to 10 times more effective than isoniazid, the leading anti-tuberculosis drug.

28 Mar 2006

Study provides a boost for efforts to reverse type-1 diabetes

Researchers have been able to confirm most but not all of the results of a high-profile study that brought new hope to diabetes patients. This study provides a boost for efforts to reverse type-1 diabetes in recently diagnosed patients but not for efforts to grow new islets from spleens.

27 Mar 2006

Gene therapy treatment for brain tumours and infections

In a study published in the March 15 issue of The Journal of Immunology, researchers at Board of Governors' Gene Therapeutics Research Institute at Cedars-Sinai Medical Center have developed a way to overcome immune privilege in the brain to eradicate potentially deadly brain tumors such as glioblastoma multiforme and other types of brain infections.

27 Mar 2006

Novel therapy for chronic graft-versus-host disease (GVHD) using Rituximab

Dana-Farber researchers found that rituximab reduced the severity of chronic graft-versus-host disease (GVHD) in 70 percent of the study participants.

27 Mar 2006

Marital strain appears to matter for health as individuals age

Researchers have found that marital strain accelerates the typical decline in self-rated physical health that occurs over time and that this adverse effect is greater at older ages.

27 Mar 2006

Phagocytosis depends more on particle shape than size

The research, which has far-reaching implications for immunology, vaccine development and drug delivery, is published today online in the Proceedings of the National Academy of Sciences by Samir Mitragotri, a UCSB professor of chemical engineering, and graduate student Julie A. Champion. The paper will be published in print on March 28.

23 Mar 2006

Remicade (infliximab) gains Australian approval for treatment of early rheumatoid arthritis

Schering-Plough Corporation today announced that the Therapeutic Goods Administration of the Department of Health and Ageing in Australia has revised the indication of Remicade (infliximab) to include the treatment of early rheumatoid arthritis (RA) and approved a new indication for psoriatic arthritis (PsA).

23 Mar 2006

Researchers combat tuberculosis - help may come from protective protein

Most Americans think of tuberculosis as a disease of the past, but with HIV and drug-resistant strains fueling epidemics in India and Africa, TB kills someone every six seconds across the world.

23 Mar 2006

Zinc's role in Alzheimer's disease

Zinc may be a familiar dietary supplement to millions of health-conscious people, but it remains a mystery metal to scientists who study zinc's role in Alzheimer's disease, stroke and other health problems.

23 Mar 2006

Immune system protein LL-37 critical in controlling replication of vaccinia virus

Scientists supported by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), have identified a defect in the immune response of people with the skin condition atopic dermatitis that puts them at risk of developing serious complications following smallpox vaccination.

23 Mar 2006

Potential therapeutic targets against serious side effects of smallpox vaccine

Smallpox is considered a potential terrorist weapon, but millions of people in the United States are currently advised not to get a vaccine to the disease because they are susceptible to developing a severe adverse reaction.

23 Mar 2006

Scientists create new molecule that holds promise in fighting disease via gene therapy

Inherited diseases, as well as many cancers and cardiovascular diseases, may eventually be helped by this approach, which delivers therapeutic genes directly to cells. These genes can correct genetic defects, for example, or help the body's immune system fight cancer cells.

23 Mar 2006

First evidence that dendritic cells show unprecedented sensitivity to thimerosal

A team of cell biologists, toxicologists and molecular bioscientists at UC Davis has published a study connecting thimerosal with disruptions in antigen-presenting cells known as dendritic cells obtained from mice.

22 Mar 2006

Zoologists succeed for the first time in transforming stem cells in freshwater polyps

Stem cells are versatile all-rounders. In the medical field, high hopes are resting on these miracle workers. However, we still understand very little about them.

21 Mar 2006

Swedish scientists move closer to a cancer vaccine

Scientists at Karolinska Institutet in Sweden have helped to identify a molecule that can be used as a vaccination agent against growing cancer tumours. Although the results are so far based on animal experiments, they point to new methods of treating metastases.

21 Mar 2006

Gene discovered that causes dry skin and leads to eczema and asthma

Experts, lead by the University of Dundee, have discovered the gene which causes genetic skin conditions affecting millions of people.

21 Mar 2006

A newly recognized type of immune cell may play an important role in causing asthma

...perhaps explaining why current therapies sometimes fail, report researchers from Children's Hospital Boston in the New England Journal of Medicine.

21 Mar 2006

Immune System News and Research

Discovery of a gene that drives anthrax bacteria's toxic effects

RNAi-based inhibitors for created for nearly every human and mouse gene - available to all genetic researchers

Procedure cures some diabetic mice, but not in the way previously reported

Researchers find compound 10 times more effective than isoniazid, the leading anti-tuberculosis drug

Study provides a boost for efforts to reverse type-1 diabetes

Gene therapy treatment for brain tumours and infections

Novel therapy for chronic graft-versus-host disease (GVHD) using Rituximab

Marital strain appears to matter for health as individuals age

Phagocytosis depends more on particle shape than size

Remicade (infliximab) gains Australian approval for treatment of early rheumatoid arthritis

Researchers combat tuberculosis - help may come from protective protein

Zinc's role in Alzheimer's disease

Immune system protein LL-37 critical in controlling replication of vaccinia virus

Potential therapeutic targets against serious side effects of smallpox vaccine

Scientists create new molecule that holds promise in fighting disease via gene therapy

First evidence that dendritic cells show unprecedented sensitivity to thimerosal

Zoologists succeed for the first time in transforming stem cells in freshwater polyps

Swedish scientists move closer to a cancer vaccine

Gene discovered that causes dry skin and leads to eczema and asthma

A newly recognized type of immune cell may play an important role in causing asthma

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