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MGH researchers discover how triple-negative breast cancer can evade powerful drugs

Massachusetts General Hospital researchers have identified for the first time how a highly aggressive form of breast cancer can evade one of the most powerful and effective drugs used to treat it, reporting their findings in Cancer Discovery, a journal of the American Association for Cancer Research.

17 Aug 2021

Researchers confirm the speed, simplicity and accuracy of new COVID-19 testing method

Researchers from the University of Birmingham, U.K., have confirmed the speed, accuracy, and simplicity of a novel, a highly sensitive testing method for COVID-19 that can be deployed at entertainment venues, airport arrival terminals, and in remote settings where clinical testing laboratories are not available.

17 Aug 2021

Sino Biological Announces Successful Closing of 4.98 Billion RMB Public Offering and Listing on the Shenzhen ChiNext Stock Exchange

Sino Biological, Inc. (“Sino Biological” or the “Company”), a biotechnology company which provides biological research reagents and related technical contract research services, announced a successful listing on the Shenzhen Stock Exchange subsidiary ChiNext under the stock abbreviation Sino Biological and stock code 301047.

From Sino Biological Inc. 17 Aug 2021

Vaccinating previously infected induces more potent antibodies less susceptible to escape from SARS-CoV-2 variants

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is the causal agent of the coronavirus disease 2019 (COVID-19) pandemic, which has claimed more than 4.3 million lives worldwide. Even after implementing various measures, such as vaccination and social restrictions, SARS-CoV-2 and its variants of concern (VoC) leave the world's public health systems and economies in turmoil.

16 Aug 2021

Study identifies mechanism of resistance and presents a much-needed target for advanced leukemias

Too many "exhausted" T cells left in the wake of aggressive chemotherapy regimens for patients with advanced chronic lymphocytic leukemia (CLL) make it more challenging for chimeric antigen receptor (CAR) T cell therapy to do its job.

16 Aug 2021

SARS-CoV-2 Spike may trigger production of antibodies that cross-react with human thrombopoietin to induce thrombocytopenia

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infected individuals often suffer from thrombocytopenia, a condition associated with low platelet counts. The cytokine thrombopoietin regulates platelet count. Previous studies have reported that thrombocytopenia can increase the coronavirus disease 2019 (COVID-19) mortality rate by about five times.

16 Aug 2021

Certain intestinal bacteria induce cross-reactive IgA responses to the SARS-CoV-2 spike RBD

A new study finds that human gut bacteria can induce antibodies of the immunoglobulin A (IgA) subtype that cross-react with the SARS-CoV-2 spike RBD.

15 Aug 2021

Immunotherapy pairs ultrasound with immune cells to destroy tumors without toxic side effects

Bioengineers at the University of California San Diego have developed a cancer immunotherapy that pairs ultrasound with cancer-killing immune cells to destroy malignant tumors while sparing normal tissue.

12 Aug 2021

Novel blood test as adjunct to MRI improves prostate cancer screening

Researchers at Karolinska Institutet in Sweden recently reported that magnetic resonance imaging (MRI) could reduce overdiagnoses and thereby improve prostate cancer screening.

12 Aug 2021

Reading, ’rithmetic and resisting covid: The new 3 R’s as kids head back to school

When kids head back to school this fall, for some it will be the first time they've been in a real classroom with other students since the pandemic began.

12 Aug 2021

COVID-19 vaccine likely protects people living with HIV, study shows

A Johns Hopkins Medicine research team has shown that people living with the human immunodeficiency virus (HIV) are likely to be protected against SARS-CoV-2, the virus that causes COVID-19, if they are fully vaccinated.

11 Aug 2021

Natural vs. vaccine-induced COVID-19 immunity

A new paper discusses the protection offered by immunity against COVID-19 following vaccination as compared to natural infection.

10 Aug 2021

Systematic anatomical study specifies guidelines for performing nasopharyngeal swabs

Since the start of the coronavirus pandemic, thousands of nasopharyngeal swabs have been taken in Austria - millions worldwide.

10 Aug 2021

New protocol for the study of SARS-CoV-2's medium and long-term outcomes

The clinical symptoms of the severe COVID-19 have been well described. In addition, scientists have defined the post-acute COVID-19 as the development of sequelae or persistence of symptoms several weeks after the onset of COVID-19 symptoms. In some cases, the symptoms persist for around 3-4 weeks, and in other cases of chronic COVID-19, symptoms may persist beyond 12 weeks from the onset of symptoms.

9 Aug 2021

Study of antibody responses to COVID-19 mRNA vaccine in convalescent individuals

In addition to clinical trials conducted to determine the safety and efficacy of the mRNA vaccines, additional studies began describing the serological response to the vaccines under "real-world" conditions, especially with the onset of the SARS-CoV-2 variants and case reports of vaccine escape.

9 Aug 2021

New insight into impact of SARS-CoV-2 mutations on receptor binding

A recent study by Canadian researchers, currently available on the bioRxiv* preprint server, contributes to the growing body of literature on emerging variants of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by appraising the impact of single mutations on their overall antigenicity and binding affinity for the angiotensin-converting enzyme 2 (ACE2) receptor.

9 Aug 2021

Study reports on COVID-19 vaccine-related adverse events in young Japanese population

A new study from Japan, released as a medRxiv* preprint, describes the adverse effects associated with the vaccine. Such data is crucial in delineating the safety and efficacy of this intervention in various age groups.

6 Aug 2021

Magnetic nanoparticles could enhance the efficacy of cancer immunotherapy

Boosting the function of natural killer cells with magnetic nanoparticles could make cancer immunotherapy more efficient.

6 Aug 2021

Nasal version of AstraZeneca SARS-CoV-2 vaccine prevents infection in animal models

Scientists evaluate the use of ChAdOx1 nCoV-19 as a potential intranasal (IN) vaccine candidate in hamster and rhesus macaque models.

3 Aug 2021

Comprehensive review: Nanomaterial-based delivery vehicles for cancer vaccine development

Over the years, significant advancements in cancer research have led us to the next step in cancer therapy – vaccines for cancer! However, the direct use of these vaccines in the affected individuals have often failed to bring about desired anti-tumor effects.

3 Aug 2021

Antigen News and Research

MGH researchers discover how triple-negative breast cancer can evade powerful drugs

Researchers confirm the speed, simplicity and accuracy of new COVID-19 testing method

Sino Biological Announces Successful Closing of 4.98 Billion RMB Public Offering and Listing on the Shenzhen ChiNext Stock Exchange

Vaccinating previously infected induces more potent antibodies less susceptible to escape from SARS-CoV-2 variants

Study identifies mechanism of resistance and presents a much-needed target for advanced leukemias

SARS-CoV-2 Spike may trigger production of antibodies that cross-react with human thrombopoietin to induce thrombocytopenia

Certain intestinal bacteria induce cross-reactive IgA responses to the SARS-CoV-2 spike RBD

Immunotherapy pairs ultrasound with immune cells to destroy tumors without toxic side effects

Novel blood test as adjunct to MRI improves prostate cancer screening

Reading, ’rithmetic and resisting covid: The new 3 R’s as kids head back to school

COVID-19 vaccine likely protects people living with HIV, study shows

Natural vs. vaccine-induced COVID-19 immunity

Systematic anatomical study specifies guidelines for performing nasopharyngeal swabs

New protocol for the study of SARS-CoV-2's medium and long-term outcomes

Study of antibody responses to COVID-19 mRNA vaccine in convalescent individuals

New insight into impact of SARS-CoV-2 mutations on receptor binding

Study reports on COVID-19 vaccine-related adverse events in young Japanese population

Magnetic nanoparticles could enhance the efficacy of cancer immunotherapy

Nasal version of AstraZeneca SARS-CoV-2 vaccine prevents infection in animal models

Comprehensive review: Nanomaterial-based delivery vehicles for cancer vaccine development

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

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Bringing real-time analytics to downstream bioprocess monitoring

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Evaluating new approaches for rare disease genomics