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New matching system enables world's first four-way liver exchange

In a breakthrough in liver transplantation that may lead to the ability to connect more living donors and patients, a new matching system designed by a team led by Boston College economists enabled the world's first four-way liver exchange and a cascade of additional matches, researchers reported recently in the American Journal of Transplantation.

22 Aug 2023

New insights into the pathogenic mechanisms of SLC29A3 disorders

In humans, the SLC29A3 gene regulates the function of lysosomes to control waste recycling in cells such as macrophages (that engulf and destroy foreign bodies).

22 Aug 2023

High-fat diet changes gut bacteria, bile acids, and increases colorectal cancer risk

The prevalence of colorectal cancer in people under the age of 50 has risen in recent decades. One suspected reason: the increasing rate of obesity and high-fat diets.

22 Aug 2023

Strep A infections on the rise among Australians, study finds

Australia has experienced an intense surge in severe Strep A cases, similar to the northern hemisphere wave, despite differences in seasons and circulating respiratory viruses, according to a new study.

22 Aug 2023

Study identifies an endogenous bile acid that alleviates non-alcoholic fatty liver disease

A study finds that hyodeoxycholic acid alleviates non-alcoholic fatty liver disease by modulating the gut-liver axis.

22 Aug 2023

NIH supports research to understand the genome-metal interactions in nonalcoholic fatty liver disease

Wanqing Liu, Ph.D., professor of pharmaceutical sciences in the Wayne State University Eugene Applebaum College of Pharmacy and Health Sciences and of pharmacology in Wayne State's School of Medicine, received a $3 million, five-year award from the National Institute of Environmental Health Sciences of the National Institutes of Health.

21 Aug 2023

Gene therapy repairs neural connections in mice with Hurler syndrome

A new study from the University of Minnesota is the first to demonstrate the ability for gene therapy to repair neural connections for those with the rare genetic brain disorder known as Hurler syndrome.

21 Aug 2023

Alcohol-associated bowel disease: A review of the literature

Alcohol consumption is a significant risk factor for gastrointestinal diseases, including cancer. Alcohol can damage the gastrointestinal tract in several ways.

21 Aug 2023

COVID-19 associated with increased risk of developing various autoimmune diseases and risk could be attenuated by vaccination

COVID-19 can increase the risk of various autoimmune diseases; however, this risk appears to be mitigated by vaccination against COVID-19.

21 Aug 2023

Machine learning-based preeclampsia risk prediction

Study developed a machine-learning-based model using the Medical Record Longitudinal Information AI System (MERLIN).

21 Aug 2023

Associations between cardiorespiratory fitness in young men and the incidence of site-specific cancer

A recent study assessed the association between cardiorespiratory fitness and some cancers in healthy young men.

21 Aug 2023

The standard of care and recent advancements in the control of skin inflammation

Researchers discuss current therapeutic interventions for atopic dermatitis in children and adolescents.

21 Aug 2023

AI-based model indicates chest radiography as a potential biomarker of aging

A recent study developed an AI model to determine the age of individuals by analyzing chest radiographs.

21 Aug 2023

Associations between alcohol intake, cancer risk, and modifying factors in women: smoking, BMI, and MHT interactions

Researchers examined the association between moderate alcohol intake and specific cancer risks.

21 Aug 2023

Meta-analysis reports global prevalence of MAFLD of 38.8% in adults

Non-alcoholic fatty liver disease (NAFLD) is a common condition that affects up to 30% of adults in the general population.

18 Aug 2023

Cleveland Clinic London performs first augmented reality-assisted total knee replacement

Cleveland Clinic London is the first hospital in London to successfully perform a total knee replacement procedure with the assistance of an augmented reality-based surgical platform that was designed with artificial intelligence and machine learning.

18 Aug 2023

New findings could develop effective vaccines or treatments for chikungunya fever

Researchers at Albert Einstein College of Medicine have found that the virus responsible for chikungunya fever can spread directly from cell to cell - perhaps solving the longstanding mystery of how the virus, now emerging as a major health threat, can manage to escape antibodies circulating in the bloodstream.

18 Aug 2023

Study finds how low levels of the TET2 gene fuel rapid growth of acute myeloid leukemia

Scientists at City of Hope, one of the largest cancer research and treatment organizations in the United States, have identified how low levels of the TET2 gene fuel the rapid growth of acute myeloid leukemia in animal models.

17 Aug 2023

Current methods overestimate malaria parasite multiplication rates

Current methods can vastly overestimate the rates that malaria parasites are multiplying in an infected person's blood, which has important implications for determining how harmful they could be to a host, according to a new report.

17 Aug 2023

New insights into the role of liver progenitor cells in liver cancer initiation

Primary liver cancers ranked as the sixth most commonly diagnosed cancers and the third leading cause of cancer-related death in 2020. Among all primary liver cancers, HCC is the most common cancer, accounting for more than 80% of cases with a 5-year survival rate of less than 10% in Western countries.

17 Aug 2023

Liver News and Research

New matching system enables world's first four-way liver exchange

New insights into the pathogenic mechanisms of SLC29A3 disorders

High-fat diet changes gut bacteria, bile acids, and increases colorectal cancer risk

Strep A infections on the rise among Australians, study finds

Study identifies an endogenous bile acid that alleviates non-alcoholic fatty liver disease

NIH supports research to understand the genome-metal interactions in nonalcoholic fatty liver disease

Gene therapy repairs neural connections in mice with Hurler syndrome

Alcohol-associated bowel disease: A review of the literature

COVID-19 associated with increased risk of developing various autoimmune diseases and risk could be attenuated by vaccination

Machine learning-based preeclampsia risk prediction

Associations between cardiorespiratory fitness in young men and the incidence of site-specific cancer

The standard of care and recent advancements in the control of skin inflammation

AI-based model indicates chest radiography as a potential biomarker of aging

Associations between alcohol intake, cancer risk, and modifying factors in women: smoking, BMI, and MHT interactions

Meta-analysis reports global prevalence of MAFLD of 38.8% in adults

Cleveland Clinic London performs first augmented reality-assisted total knee replacement

New findings could develop effective vaccines or treatments for chikungunya fever

Study finds how low levels of the TET2 gene fuel rapid growth of acute myeloid leukemia

Current methods overestimate malaria parasite multiplication rates

New insights into the role of liver progenitor cells in liver cancer initiation

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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