Immune System News and Research

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Women suffering lupus OK to take oral contraceptives

Major study of women with either inactive or stable systemic lupus erythematosus (lupus) – a disease in which the body's immune system mistakenly attacks and damages healthy tissues of the skin, joints and internal organs – were able to take oral contraceptives without increased risk of flares, or periods of increased disease activity, that characterize the disease.

22 Dec 2005

Scientists discover how HIV infects healthy cells

Using sophisticated detection methods, researchers at the Saint Louis University Institute for Molecular Virology (IMV) have demonstrated the molecular mechanism by which the HIV virus infects, or integrates, healthy cells. The discovery could lead to new drug treatments for HIV.

22 Dec 2005

Children could be saved from neuroblastoma using antibody therapy

Combination of T cell, antibody to neuroblastoma cells and molecule that spurs T cell growth is designed to treat low initial tumor levels or small cancer cell populations that survive initial treatment, according to St. Jude.

22 Dec 2005

Extremely infectious pneumonia-like disease slips through body's immune system

A new study found that an extremely infectious pneumonia-like disease in humans slips through the immune system's usual defense mechanisms.

21 Dec 2005

Synthetic compound could arrest development of Alzheimer's

Spanish chemists have developed a promising set of synthetic compounds that one day could help slow or perhaps halt the progression of Alzheimer's disease and other neurological disorders.

21 Dec 2005

Sanofi's human bird flu vaccine tests looking good

French drug company Sanofi Pasteur says early stage trials of an experimental vaccine against H5N1 bird flu have shown it provides a good immune response in humans and is safe.

19 Dec 2005

Lupus patients safe to go back on the pill

Two new studies confirm that women who suffer from lupus, a chronic disease that can lead to inflamed kidneys, can safely take oral contraceptives without fear that the pill will worsen their condition.

19 Dec 2005

Good results with cervical cancer vaccine in young girls

Drug company GlaxoSmithKline have had a good result with their new vaccine which was designed to prevent infection with the virus that causes cervical cancer.

19 Dec 2005

The role of genes in the development of non-Hodgkin's lymphomas

An international consortium of epidemilogists - including Dr. Alexandra Nieters and Professor Nikolaus Becker of the Clinical Epidemiology Division of the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) - has conducted the first ever investigation of genetic factors in the development of non-Hodgkin’s lymphoma (NHL) in a study called InterLymph.

15 Dec 2005

65% of ovarian cancer cells sideline body's defences

Ovarian cancer tumour cells use two separate mechanisms to evade the body’s defensive reaction - and in so doing also elude a newly discovered counteraction from the surrounding tissue.

15 Dec 2005

New cell findings have implications for cancer, immune disorders

It all started 5 years ago when a University of Calgary neuroscientist sent blood from a patient with a neurological disorder to the laboratory of Dr. Marvin Fritzler, professor of medicine / biochemistry & molecular biology at the University of Calgary Faculty of Medicine.

15 Dec 2005

A colonization factor links Vibrio cholerae environmental survival and human infection

Opening a new door to an effective vaccine and therapy for a disease that strikes thousands annually, researchers at Dartmouth Medical School discovered that the bacteria that causes the intestinal disease Cholera spreads in the environment in much the same way it infects humans.

13 Dec 2005

Perimenopause critical for preventing heart disease and osteoporosis

Research in monkeys suggests that the perimenopause - the five to 10 years before a woman's menopause - is a critical time for preventing heart disease and osteoporosis.

13 Dec 2005

New treatment for chronic Immune Thrombocytopenic Purpura

Data from a Phase II study of eltrombopag, an oral investigational drug that increases the production of platelets, demonstrate that the compound was effective in increasing platelet counts in patients with chronic Immune Thrombocytopenic Purpura (ITP), a disorder characterized by episodes of frequent spontaneous bruising, mucosal bleeding, and in severe cases intracranial hemorrhage, and acute episodes of severe bleeding.

12 Dec 2005

Infections are a major cause of childhood cancer

Results from a new study of childhood cancer statistics provide further evidence that common infections affecting mother and baby could play a key role in triggering certain types of the disease.

12 Dec 2005

Garvan scientists explain stress and sickness

Garvan Institute scientists have discovered how a hormone, known as neuropeptide Y (NPY), can prevent our immune system functioning properly, paving the way for two new major opportunities for therapeutic intervention.

7 Dec 2005

New study sheds light on role of type II collagen in rheumatoid arthritis

Rheumatoid arthritis (RA) is an autoimmune disease which gradually erodes cartilage and bone and is characterised by chronic inflammation of the joints.

6 Dec 2005

Intervention in immune regulation can prevent onset of type-1 diabetes

Some forms of diabetes could feasibly be prevented. Scientists at the German Research Centre for Biotechnology (GBF) in Braunschweig recently were able to do just that in experiments with mice.

6 Dec 2005

Face transplant woman doing well

French surgeons say that the 38-year-old recipient of the world's first partial face transplant regained consciousness 24 hours after her operation and is doing well.

5 Dec 2005

Researchers move in on novel therapeutics to inhibit melanoma

Northwestern University researchers have developed a novel, three-dimensional model that allows scientists to observe how interacting with the microenvironment of metastatic melanoma cells induces normal skin cells to become similar to aggressive cancer cells that migrate and spread throughout the body.

5 Dec 2005