Animal Model News and Research

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Blueberries, a tasty intervention against age-related cognitive decline

In a recent study published in the Nutritional Neuroscience journal, researchers assessed the impact of consumption of wild blueberries on the speed of processing in mild cognitive decline.

25 Sep 2022

Coral genome reveals an alternative pathway for cysteine biosynthesis

Model animals, such as mice and fruit flies, have provided scientists with powerful insights into how cellular biology works. However, model animals are really just a guide, and it can be risky to generalize findings across animals from studying a selection of model organisms.

23 Sep 2022

New engineered peptides could prevent the superbug crisis

A recent study reports the development of a synthetic antibacterial peptide PLG0206.

22 Sep 2022

Needle-free jet injection of novel COVID-19 DNA vaccine shows promise in animal model

In a recent study posted to the bioRxiv* server, researchers at the United States Army Medical Research Institute of Infectious Diseases evaluated the immunogenicity of a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) deoxyribonucleic acid (DNA) vaccine, nCOV-S(JET), in rhesus macaques

18 Sep 2022

New drug induces similar effects as exercise to aid in the treatment of locomotor frailty

Maintaining a regular workout routine can help you look and feel great – but did you know that exercise also helps maintain your muscles and bones? People who are unable to engage in physical activity experience weakening of the muscles and bones, a condition known as locomotor frailty.

13 Sep 2022

Study helps understand how dietary therapies work for epilepsy

Calorie restriction has long been associated with reduced seizures in epilepsy. New research from Boston Children's Hospital helps explain how fasting affects neurons in the brain and could lead the way to new approaches that would avoid the need for fasting or restrictive diets. The findings were published August 30 in the journal Cell Reports.

9 Sep 2022

Neonatal ketone body plays key role in primordial follicle pool formation and regulates ovarian aging

Premature ovarian aging (POA) refers to an early decline in ovarian function; it is the main cause of infertility in elder women and is characterized by a markedly reduced ovarian reservoir.

5 Sep 2022

UTHSC team wins $2.13 million NINDS award to study early neuron development

The National Institute of Neurological Disorders and Stroke has awarded $2.13 million to a University of Tennessee Health Science Center (UTHSC) team studying how neural cells that build a functional brain are generated during embryonic and neonatal life.

2 Sep 2022

Depletion of reactive astrocytes regresses glioblastoma

A groundbreaking study at Tel Aviv University effectively eradicated glioblastoma, a highly lethal type of brain cancer. The researchers achieved the outcome using a method they developed based on their discovery of two critical mechanisms in the brain that support tumor growth and survival: one protects cancer cells from the immune system, while the other supplies the energy required for rapid tumor growth. The work found that both mechanisms are controlled by brain cells called astrocytes, and in their absence, the tumor cells die and are eliminated.

2 Sep 2022

Inhibiting a key metabolic enzyme selectively kills melanoma cells and stops tumor growth

Researchers at Sanford Burnham Prebys, led by Ze'ev Ronai, Ph.D., have shown for the first time that inhibiting a key metabolic enzyme selectively kills melanoma cells and stops tumor growth.

1 Sep 2022

Intranasally delivered neutralizing antibody protects against SARS-CoV-2 Omicron and Delta variants

The current study focused on the ability of this nmAb to neutralize Delta, Omicron, and other VOCs, as well as its efficacy when given by the intranasal route in an animal model.

1 Sep 2022

Using human tissue models to improve treatment and diagnosis of heart attacks

A heart attack, or myocardial infarction, is one of the leading causes of mortality worldwide, resulting in 18 million deaths per year.

30 Aug 2022

New labeling technique helps analyze the contents of exosomes from cells

Our cells are constantly communicating, and scientists have developed an efficient way to find out what messages they are sending in protein-packed biological suitcases called exosomes.

30 Aug 2022

Discovery paves the way for specific therapies for common form of childhood brain and spine tumor

A study conducted by researchers in Brazil, Australia, Austria and the United States has made significant discoveries about a type of pediatric cancer with no approved drugs for treatment and with a low survival rate.

29 Aug 2022

Susceptibility of deer mice and California mice to COVID-19

In a new study, researchers assessed the susceptibility of deer mice and California mice to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

25 Aug 2022

Novel member of a class of anti-diabetes drugs could help treat muscle wasting disease

Inflammatory myopathies can be challenging to treat, but a new study reports encouraging findings for patients with these debilitating conditions. Researchers from Japan have found that a novel member of a class of anti-diabetes drugs could be the key to treating patients with muscle wasting disease.

18 Aug 2022

Animal Model News and Research

Blueberries, a tasty intervention against age-related cognitive decline

Coral genome reveals an alternative pathway for cysteine biosynthesis

New engineered peptides could prevent the superbug crisis

Needle-free jet injection of novel COVID-19 DNA vaccine shows promise in animal model

New drug induces similar effects as exercise to aid in the treatment of locomotor frailty

Study helps understand how dietary therapies work for epilepsy

Neonatal ketone body plays key role in primordial follicle pool formation and regulates ovarian aging

UTHSC team wins $2.13 million NINDS award to study early neuron development

Depletion of reactive astrocytes regresses glioblastoma

Inhibiting a key metabolic enzyme selectively kills melanoma cells and stops tumor growth

Intranasally delivered neutralizing antibody protects against SARS-CoV-2 Omicron and Delta variants

Using human tissue models to improve treatment and diagnosis of heart attacks

New labeling technique helps analyze the contents of exosomes from cells

Discovery paves the way for specific therapies for common form of childhood brain and spine tumor

Susceptibility of deer mice and California mice to COVID-19

Novel member of a class of anti-diabetes drugs could help treat muscle wasting disease

Lack of strength in smooth muscle cells leads to malformations of the blood vessels, study shows

Discovery explains how impaired metabolism triggers neuroendocrine tumors in the adrenal glands

In monkeys, spike-based vaccines produce some immunity based on CD8 T-cells

How effective is tecovirimat as a treatment against monkeypox?

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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