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Blocking a naturally occurring molecule reverses deadly lung disease in preclinical models

Researchers blocked a naturally occurring molecule to reverse pulmonary arterial hypertension in preclinical models, a finding that could point to a new treatment approach for people with a rare and often fatal lung disease.

2 Sep 2026

Generative AI helps scientists design entirely new RNA transporters

Researchers at Helmholtz Munich and TUM have developed Synthetic Transfer Vehicles (STVs), an entirely new class of RNA transporters.

2 Sep 2026

Two scientists win Horwitz Prize for Rett syndrome breakthrough

Columbia University will award the 2026 Louisa Gross Horwitz Prize to Adrian Bird and Huda Zoghbi for their pioneering work on epigenetic regulation in the nervous system and its role in human neurological disease, particularly Rett syndrome.

2 Sep 2026

Scientists develop lab-grown heart tissue model for heart failure

Scientists study the underlying causes of a disease or test new potential drugs in animal models or cells obtained from human biopsy specimens before clinical trials.

2 Sep 2026

Harvard scientists discover entirely new gene regulation system in mammals

For decades, scientists have understood that each of the roughly 20,000 genes in the human body carries the instructions for a single kind of protein.

2 Sep 2026

Researchers discover dozens of genes tied to OCD and tic disorders

A Rutgers-led international collaboration has identified 36 genes that substantially raise the risk for obsessive-compulsive disorder (OCD) and chronic tic disorders – providing what two researchers said is the most detailed biological understanding of how these conditions develop – and how they might eventually be treated.

2 Sep 2026

Healthy ageing shaped by more varied biology than previously thought

Molecular changes of ageing are far more unique than previously thought, meaning two healthy individuals of identical age can experience significantly different ageing journeys.

2 Sep 2026

Study uncovers cause of abnormal breathing in Rett syndrome

Hyperventilating. Breath holding until they turn blue. This abnormal breathing is frequent and disturbing in people with Rett syndrome, a rare genetic disease.

1 Sep 2026

New brain atlas reveals insights into Huntington's, addiction, and other disorders

A region of the brain called the striatum is critical for many cognitive and motor functions, including decision-making, control of movement, habit formation, and processing of reward.

1 Sep 2026

Blocking a key protein protects against metabolic liver damage

Obesity-related metabolic liver disease affects hundreds of millions of people worldwide, but only some fraction of those livers develop scarring, become inflamed, and eventually fail. University of Utah researchers have identified a protein, EFHD1, that appears to drive that transition by triggering an out-of-place antiviral immune response.

1 Sep 2026

DARPA funds project to build wireless yeast DNA printer

The Defense Advanced Research Projects Agency (DARPA) has tasked scientists with developing a system that can receive instructions and synthesize a sequence of DNA or RNA without any chemical input. Think wireless DNA printer.

1 Sep 2026

New scLS algorithm advances gene expression trajectory analysis

Single-cell RNA sequencing (scRNA-seq) is a method to measure gene expression of individual cells, allowing observation of various cellular processes, including cell differentiation, the cell cycle, and stimulus-response for each unique cell instead of averaging across millions of cells.

1 Sep 2026

Study identifies 36 risk genes for OCD and tic disorders

1 Sep 2026

Study links human gut bacteria to levels of key chemicals in the brain

The neuroactive potential of bacteria living in the human gut is associated with levels of key chemicals in the brain, according to a new study from the University of Surrey and the University of Roehampton.

1 Sep 2026

AI platform uncovers new molecular targets for Alzheimer's disease

Groundbreaking study published in Alzheimer's & Dementia reveals the crucial links between the NAD⁺-mitophagy axis and neurodegeneration.

1 Sep 2026

AI tools map tumor architecture to predict treatment response

Spatial transcriptomics is a powerful tool to create a detailed map of not just how genes are expressed in a piece of tissue, but also where genetic activity takes place in different cells and locations within the tissue.

31 Aug 2026

Lifestyle factors aggravate genetic causes of male infertility, study finds

Lifestyle factors can worsen the effects of genetic causes of male infertility, finds new research that could help explain why men carrying similar genetic mutations often experience different levels of fertility impairment.

31 Aug 2026

FDA approves daraxonrasib for metastatic pancreatic cancer following landmark clinical trial led by Dana-Farber

The U.S. Food and Drug Administration (FDA) has approved daraxonrasib, an oral multi-selective RAS(ON) inhibitor, for adults with metastatic pancreatic adenocarcinoma who have received at least one prior systemic therapy or are not candidates for multiagent systemic therapy.

From Dana-Farber Cancer Institute, Inc. 29 Aug 2026

Paternal sperm epigenetics may help explain early pregnancy loss

When a pregnancy ends early and unexplained, the search for answers usually begins with the mother. Lacey Luense, Ph.D., wants to know what the father's sperm might have to do with it.

28 Aug 2026

Stanford scientists develop an ultracompact gene activation tool

The ability to precisely adjust the expression of genes inside the human body - ramping up protective ones and tamping down harmful ones - holds enormous potential for treating and preventing disease.

28 Aug 2026