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Study: Autism risk genes are largely consistent across different human ancestries

A new study, co-led by researchers at the Icahn School of Medicine at Mount Sinai and published March 30 in Nature Medicine [https://doi.org/ 10.1038/s41591-026-04228-6], demonstrates that genes associated with autism risk are largely the same across people of different ancestries.

30 Mar 2026

New initiative aims to scale individualized therapies for rare diseases

Critical Path Institute (C-Path) today announced the launch of One to Millions, a global, multi-stakeholder public-private initiative to enable scalable development of advanced therapies for highly individualized conditions.

26 Mar 2026

Obesity-driven organ enlargement may boost cancer risk

Scientists at City of Hope® and TGen (part of City of Hope) are the first to explain a major mechanism for why gaining excess weight increases your risk of cancer.

26 Mar 2026

New study maps global immune gene diversity across multiple populations

Inherited variations in antibody genes can affect how we respond to infections and vaccines, show two new studies from Karolinska Institutet in Sweden, published in the journal Immunity.

26 Mar 2026

4D digital heart model transforms treatment for heart failure patients

A made-in-Calgary 4D heart model is transforming treatment for heart failure patients having a specialized pacemaker inserted, called cardiac resynchronization therapy (CRT).

24 Mar 2026

Webinar introduces advanced bioinformatics tool to interpret mutations in cancer genomes

A free open-access webinar will introduce the Cancer Genome Interpreter (CGI), an advanced bioinformatics tool to interpret mutations in cancer genomes developed by IRB Barcelona and co-created with European hospitals to turn complex cancer genomics into actionable insights.

23 Mar 2026

New computational method links individual cells to patient outcomes

A computational method called scSurv, developed by researchers at Institute of Science Tokyo, links individual cells to patient outcomes using widely available bulk RNA sequencing data.

23 Mar 2026

Liquid biopsy enables rapid diagnosis of Burkitt lymphoma in Africa

In a study published today in Nature Medicine, researchers from the University of Oxford and the Muhimbili University of Health and Allied Sciences (MUHAS) in Dar es salaam, Tanzania have shown that a minimally invasive "liquid biopsy" test can diagnose Burkitt lymphoma rapidly and accurately in sub-Saharan Africa, where delays in traditional testing often prove fatal.

19 Mar 2026

Study reveals racial differences in early Alzheimer's brain changes

A team of researchers at the USC Mark and Mary Stevens Neuroimaging and Informatics Institute (Stevens INI) at the Keck School of Medicine of USC has identified important differences in how early Alzheimer's disease-related brain changes appear across racial and ethnic groups, underscoring the need for more inclusive approaches to studying and diagnosing the disease.

12 Mar 2026

New protein target for safer lung cancer therapy

Researchers at the University of Gothenburg have identified a protein linked to an increased risk of metastasis and recurrence in lung cancer. The findings are presented in a study that paves the way for new precision medicine approaches, particularly for older patients.

12 Mar 2026

Dual-positive hybrid cells linked to shorter survival in advanced breast cancer

An enigmatic type of circulating tumor cell called a dual-positive (DP) cell is associated with shorter survival time in patients with advanced breast cancer, according to a study led by investigators at Weill Cornell Medicine and NewYork-Presbyterian.

11 Mar 2026

How somatic mutations shape disease and reveal new drug targets

Researchers reviewed how somatic mutations accumulate in normal and diseased tissues, showing that natural selection can expand clones that influence disease risk, tissue adaptation, or cellular resilience. The study proposes somatic genomics as a powerful strategy to uncover disease mechanisms and identify new therapeutic targets across multiple conditions.

8 Mar 2026

NIH grant supports research on immune-related receptor in neurons

Florida Atlantic University has received a $2.4 million grant from the National Institutes of Health to investigate how an immune-related receptor in neurons plays a fundamental role in brain function, behavior and psychiatric health.

6 Mar 2026

Neural circuit mechanisms explain how chronic sleep loss disrupts social memory

Social memory—the ability to recognize familiar individuals and distinguish them from strangers—is fundamental to social cognition.

5 Mar 2026

New collaboration explores familial inflammatory bowel disease in Saudi Arabia

Mount Sinai and King Saud University Medical City in Riyadh, Saudi Arabia, today announced a three-year collaboration aimed at better understanding why inflammatory bowel disease (IBD) runs in some Saudi families, and how that knowledge can lead to risk ascertainment, earlier diagnosis and more personalized treatment options.

3 Mar 2026

Targeted PET/CT tracer improves early prediction of treatment response in rheumatoid arthritis patients

A new targeted PET/CT tracer can detect treatment response in rheumatoid arthritis patients in as little as four weeks, and potentially even at the start of treatment, according to new research published in The Journal of Nuclear Medicine.

27 Feb 2026

New biomarkers for targeted gastric therapy

HER2-positive gastric cancer accounts for a substantial proportion of advanced cases and has long been treated with HER2-targeted therapies. While trastuzumab deruxtecan has shown superior activity compared with earlier agents, most patients either fail to respond initially or eventually develop resistance.

26 Feb 2026

Serial liquid biopsies reveal evolution in advanced prostate cancer

A new study using serial liquid biopsies to track how metastatic prostate cancer evolves under treatment pressure showed that androgen receptor (AR) alterations consistently emerged and were linked to poorer outcomes across therapies.

26 Feb 2026

Imaging technique can objectively identify a recently recognized type of dementia, LATE

A novel quantitative PET- and MRI-based imaging approach can objectively identify a recently recognized type of dementia--limbic-predominant age-related TDP-43 encephalopathy, or LATE--that is often mistaken as Alzheimer's disease.

26 Feb 2026

Georgia State experts to play a key role in the largest study of profound autism

Experts from the Translational Research in Neuroimaging and Data Science (TReNDS) Center at Georgia State University will play a key role in the largest study ever conducted to investigate the causes of profound autism in children and develop possible treatments.

26 Feb 2026