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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Prime editing offers promising path to permanent treatment for cystic fibrosis

Cystic fibrosis is one of the most common genetic disorders, causing thick mucus build-up in the lungs and other parts of the body, breathing problems, and infection.

11 Jul 2024

Archaeal, fungal, viral, as well as bacterial, functional makers for autism spectrum disorder in children

Researchers investigated the associations between multikingdom gut microbiome components and functional markers with autism spectrum disorder through metagenomic sequencing of children's fecal samples.

11 Jul 2024

Salads under scrutiny: Study reveals contamination risks and solutions in ready-to-eat salads

The research paper highlights critical contamination points in the production of ready-to-eat salads and discusses solutions to ensure microbiological safety and health.

10 Jul 2024

Cryo-EM reveals structural dynamics of RNAP-DNA interactions during transcription initiation

Every living cell transcribes DNA into RNA. This process begins when an enzyme called RNA polymerase (RNAP) clamps onto DNA. Within a few hundred milliseconds, the DNA double helix unwinds to form a node known as the transcription bubble, so that one exposed DNA strand can be copied into a complementary RNA strand.

10 Jul 2024

Efficient multi-site genome editing with retron-derived multitrons

Genome editing has become a widely adopted technology to modify DNA in cells, allowing scientists to study diseases in the lab and develop therapies that repair disease-causing mutations.

10 Jul 2024

Exploring the benefits of miniaturizing NGS library preparation

In this interview, Huw Rees, a field application scientist at SPT Labtech, discusses the benefits of miniaturization in NGS library preparation and how using mosquito® can give you more value for your money.

From SPT Labtech 10 Jul 2024

Scientists identify over 5,000 genetic variants that enable certain cancers to thrive

Researchers performed saturation genome editing of the BAP1, whose dysfunction is related to cancer and impaired neurodevelopment.

10 Jul 2024

60 years in the making: Nanoparticles revolutionize nucleotide delivery

Researchers trace the 60-year evolution of lipid nanoparticles (LNPs) for nucleic acid delivery, highlighting their potential to revolutionize gene therapy with safer and more effective treatments.

10 Jul 2024

Targeted alpha therapy offers hope for glioblastoma patients

A new approach to treating the most malignant type of brain cancer – glioblastoma – has shown strong promise in pre-clinical settings, raising hopes of increasing current average survival rates beyond 18 months.

10 Jul 2024

Fungal endophytes: A promising frontier for breast cancer treatment

A recent study in Heliyon highlights the potential of fungal endophytes in developing novel anti-cancer agents, specifically targeting breast cancer therapy.

10 Jul 2024

INTEGRA Biosciences’ pipettes help to cultivate success in agriculture

The National Agricultural Research and Development Institute (NARDI) in Fundulea, Romania, relies on electronic multichannel pipettes from INTEGRA Biosciences to streamline its liquid handling workflows.

From INTEGRA Biosciences 9 Jul 2024

Non-invasive saliva test could identify children missing tetanus immunity

University of Birmingham experts are developing a non-invasive saliva test that - within 15 minutes - might identify children across the Global South missing immunity to tetanus who may also have missed out on essential vaccines.

8 Jul 2024

UC San Diego Health offers new bladder-saving gene therapy to treat localized bladder cancer

UC San Diego Health is the first health system in San Diego County to offer a new bladder-saving gene therapy to treat localized bladder cancer.

8 Jul 2024

New urine-based test holds great promise for early detection and prevention of cervical cancer

Cervical cancer is one of the most common cancers in women, with approximately 660,000 new cases and 350,000 deaths worldwide in 2022 alone.

8 Jul 2024

Discovery of TRPC5 gene's role in obesity and postnatal depression offers hope for new treatments

Scientists have identified a gene which, when missing or impaired, can cause obesity, behavioral problems and, in mothers, postnatal depression. The discovery, reported today in Cell, may have wider implications for the treatment of postnatal depression, with a study in mice suggesting that oxytocin may alleviate symptoms.

8 Jul 2024

Scientists identify over 5000 high-risk cancer gene variants

Over 5,000 genetic variants that enable certain cancers to thrive have been identified by scientists, along with a potential therapeutic target to treat or even prevent these cancers from developing.

8 Jul 2024

Machine learning identifies cancer-driving mutations at CTCF binding sites

Researchers developed a machine learning tool, CTCF-INSITE, to identify mutational hotspots at persistent CTCF binding sites across various cancers, highlighting their role in genomic structure disruption and cancer progression.

7 Jul 2024

Phages use selfish DNA to outmaneuver competitors

Curious bits of DNA tucked inside genomes across all kingdoms of life historically have been disregarded since they don't seem to have a role to play in the competition for survival.

5 Jul 2024

Insilico Medicine and Fosun Pharma deliver second preclinical candidate for solid tumor treatment

Insilico Medicine("Insilico"), a clinical-stage generative artificial intelligence (AI)-driven drug discovery company, has successfully delivered the second preclinical candidate compound (PCC) in its collaboration with Fosun Pharma in June 2024, a potential innovative therapeutic using synthetic lethal strategy for the treatment of solid tumors.

5 Jul 2024

Scientists map all the possible outcomes of changes to key tumor-suppressing gene

Researchers at the Francis Crick Institute have mapped all the possible outcomes of changes to a tumor-suppressing gene called VHL, the first step in a huge research endeavor to unpick the outcomes of tens of thousands of genetic variations in genes associated with cancer.

5 Jul 2024

DNA News and Research

Further Reading

Prime editing offers promising path to permanent treatment for cystic fibrosis

Archaeal, fungal, viral, as well as bacterial, functional makers for autism spectrum disorder in children

Salads under scrutiny: Study reveals contamination risks and solutions in ready-to-eat salads

Cryo-EM reveals structural dynamics of RNAP-DNA interactions during transcription initiation

Efficient multi-site genome editing with retron-derived multitrons

Exploring the benefits of miniaturizing NGS library preparation

Scientists identify over 5,000 genetic variants that enable certain cancers to thrive

60 years in the making: Nanoparticles revolutionize nucleotide delivery

Targeted alpha therapy offers hope for glioblastoma patients

Fungal endophytes: A promising frontier for breast cancer treatment

INTEGRA Biosciences’ pipettes help to cultivate success in agriculture

Non-invasive saliva test could identify children missing tetanus immunity

UC San Diego Health offers new bladder-saving gene therapy to treat localized bladder cancer

New urine-based test holds great promise for early detection and prevention of cervical cancer

Discovery of TRPC5 gene's role in obesity and postnatal depression offers hope for new treatments

Scientists identify over 5000 high-risk cancer gene variants

Machine learning identifies cancer-driving mutations at CTCF binding sites

Phages use selfish DNA to outmaneuver competitors

Insilico Medicine and Fosun Pharma deliver second preclinical candidate for solid tumor treatment

Scientists map all the possible outcomes of changes to key tumor-suppressing gene

Understanding the DNA Damage Response in Innate Immunity eBook

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