Enzyme News and Research

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The efficacy of honokiol in inhibiting SARS-CoV-2 replication in cell culture

Researchers evaluated the efficacy of honokiol in inhibiting SARS-CoV-2 replication in cell cultures.

2 Aug 2022

Novel subset of immune cells confers fast-acting and lasting protection against ischemic stroke

A unique subset of white blood cells confers fast-acting and lasting protection against ischemic stroke in mice, University of Pittsburgh neurologists and immunologists reported in the Journal of Clinical Investigation today.

1 Aug 2022

How does COVID-19 affect sexual and bladder functions in men?

Researchers discuss the impact of COVID-19 on the urogenital health of males.

1 Aug 2022

Scientists report exceptional selection pressure on coronavirus host receptors in bats compared to other mammals

A new study examined how ACE2 and DPP4 has evolved using the bat genetic dataset as well as other mammal species.

1 Aug 2022

The recent progress in investigating the inhibitory impact of nanosponges and antiviral delivery against SARS-CoV-2

Researchers assessed the potential of nanosponges against SARS-CoV-2.

1 Aug 2022

How and when do de novo SARS-CoV-2 spike mutations emerge?

Researchers evaluated viral mutations in two patients with persistent SARS-CoV-2 infection.

1 Aug 2022

Study indicates that cross-reactive immunity against SARS-CoV-2 N protein was present in Africa prior to the pandemic

Researchers assessed the pre-existing cross-protective immune responses against SARS-CoV-2 nucleocapsid protein and spike protein before the COVID-19 pandemic in individuals residing in North and South America, Europe and Africa in vitro and in vivo.

1 Aug 2022

The susceptibility of transplantable ocular tissues to SARS-CoV-2 lineage A variant infection

Researchers evaluated the infectivity of two SARS-CoV-2 A lineage variants on human ocular tissues in vitro.

1 Aug 2022

Decoy ACE2 receptors broadly neutralize SARS-CoV-2 variants

Researchers review current developments in preclinical studies associated with recombinant ACE2 decoy receptors against coronaviruses.

31 Jul 2022

Green methodologies for the synthesis of heterocyclic compounds

The book "Key Heterocyclic Cores for Smart Anticancer Drug–Design Part I" is an overview of various green methodologies for the synthesis of these heterocyclic cores.

29 Jul 2022

RINVOQ® (upadacitinib) Approved by European Commission as an Oral Treatment for Adults with Active Non-Radiographic Axial Spondyloarthritis

With this approval, RINVOQ® is the first and only Janus Kinase inhibitor approved to treat patients across the spectrum of axial spondyloarthritis (nr-axSpA and ankylosing spondylitis) in the EU.

From AbbVie 29 Jul 2022

SARS-CoV-2 spike subunit 2–targeted vaccine could more effectively combat all human coronaviruses

In a new study, researchers evidenced that the S2 subunit of SARS-CoV-2 spike (S) could be an integral component of a pan-coronavirus vaccine.

29 Jul 2022

Researchers report near-atomic-resolution images of nitrogenase during catalysis using cryo-EM

Previously, it has been impossible to capture the high-resolution images of nitrogenase, the only enzyme capable of reducing nitrogen into ammonia, during catalytic action.

29 Jul 2022

New glioma drug may represent a paradigm for designing therapeutics exploiting specific DNA repair

A new class of glioma drugs exploits tumors that lack the DNA repair enzyme MGMT; the drugs lead to the generation of cytotoxic DNA and selectively kill tumor cells without the risk of resistance, researchers report.

29 Jul 2022

Novel algorithm identifies adverse drug events across the seven pediatric development stages

Side effects from pediatric drug treatment are responsible for nearly 10 percent of childhood hospitalizations, with nearly half of those being life-threatening. Despite the need to know more about these drugs and the adverse events they can have on children, little evidence is currently available.

28 Jul 2022

Scientists discover a new set of chemical reactions to generate amino acids and nucleic acids

Four billion years ago, the Earth looked very different than it does today, devoid of life and covered by a vast ocean. Over the course of millions of years, in that primordial soup, life emerged. Researchers have long theorized how molecules came together to spark this transition.

28 Jul 2022

Enzyme News and Research

The efficacy of honokiol in inhibiting SARS-CoV-2 replication in cell culture

Novel subset of immune cells confers fast-acting and lasting protection against ischemic stroke

How does COVID-19 affect sexual and bladder functions in men?

Scientists report exceptional selection pressure on coronavirus host receptors in bats compared to other mammals

The recent progress in investigating the inhibitory impact of nanosponges and antiviral delivery against SARS-CoV-2

How and when do de novo SARS-CoV-2 spike mutations emerge?

Study indicates that cross-reactive immunity against SARS-CoV-2 N protein was present in Africa prior to the pandemic

The susceptibility of transplantable ocular tissues to SARS-CoV-2 lineage A variant infection

Decoy ACE2 receptors broadly neutralize SARS-CoV-2 variants

Green methodologies for the synthesis of heterocyclic compounds

RINVOQ® (upadacitinib) Approved by European Commission as an Oral Treatment for Adults with Active Non-Radiographic Axial Spondyloarthritis

SARS-CoV-2 spike subunit 2–targeted vaccine could more effectively combat all human coronaviruses

Researchers report near-atomic-resolution images of nitrogenase during catalysis using cryo-EM

New glioma drug may represent a paradigm for designing therapeutics exploiting specific DNA repair

Novel algorithm identifies adverse drug events across the seven pediatric development stages

Scientists discover a new set of chemical reactions to generate amino acids and nucleic acids

The bat-virus relationship examined

TMPRSS2 protein, a novel target for SARS-CoV-2 drugs

Predicting viral antibody escape using pre-pandemic data

Cross-reactive SARS-CoV-2 antibodies after exposure to avian coronavirus vaccine

Understanding the DNA Damage Response in Innate Immunity eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo