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Global effort enters an active growth phase to preserve the Earth's microbial heritage

A global effort to create a "microbial Noah's Ark" to preserve the world's diverse collection of healthy microbes before they disappear is now entering an active growth phase.

27 Jun 2025

Reconstructing 50,000 thousand years of Indian ancestry using whole-genome data

India's population is genetically one of the most diverse in the world, yet it remains underrepresented in global datasets.

27 Jun 2025

Study maps HER2 mutations in lung cancer patients from Northeastern Brazil

A new research paper was published in Volume 16 of Oncotarget on June 17, 2025, titled "Molecular landscape of HER2-mutated non-small cell lung cancer in Northeastern Brazil: Clinical, histopathological, and genomic insights."

27 Jun 2025

Protein cleavage mechanism sheds light on severe childhood ciliopathies

New research by Sumeda Nandadasa, PhD, reveals how a key protein associated with Meckel-Gruber syndrome, nephronophthisis, Joubert syndrome and other ciliopathies is cut in half to perform two separate functions, both of which are fundamental to the healthy development of children.

27 Jun 2025

Insilico Medicine begins clinical trial for AI-designed cancer drug ISM3412

Insilico Medicine, a clinical-stage biotechnology company driven by generative artificial intelligence (AI), today announces that the first patient has been dosed in a global multicenter clinical trial (NCT06414460) to evaluate ISM3412, a potentially best-in-class, AI-empowered MAT2A inhibitor with novel structure, in patients with locally advanced and metastatic solid tumors.

27 Jun 2025

Soil bacterium offers clues for new bioactive compounds

A recent study by an interdisciplinary research team shows how a soil bacterium can become a source of inspiration in the search of new active substances.

27 Jun 2025

Study explores how a familiar spice tackles the toughest cancer cells

Researchers found that clinically achievable doses of curcumin, the active compound in turmeric, target and suppress colorectal cancer stem-like cells, especially in early adenomas. Curcumin shifts these cells toward differentiation, delays tumor growth in mice, and may offer a safe preventive strategy.

27 Jun 2025

New technology brings antibiotic resistance surveillance to the field

Antibiotics are one of the greatest triumphs in the history of medical science - but these lifesaving tools have a dark side.

26 Jun 2025

Do spicy foods help or hurt your gut health?

Capsaicin, the spicy compound in chili peppers, not only influences inflammation, metabolism, and cancer risk but also shapes the gut microbiome in complex, context-dependent ways. This comprehensive review highlights both the therapeutic promise and potential risks of capsaicin, calling for deeper research into its microbiome-mediated effects.

26 Jun 2025

Partial match stem cell transplants show strong survival rates

Blood cancer patients who may have previously struggled to find a donor for transplantation now have more options.

26 Jun 2025

Can your athletic past raise your risk for atrial fibrillation?

Elite retired rowers face a nearly threefold increased risk of atrial fibrillation compared to the general population, driven by a combination of long-term cardiac remodelling and underlying polygenic genetic susceptibility.

26 Jun 2025

Largest Indian genome study reveals 50,000 years of genetic history

With around 5,000 different ethno-linguistic and religious groups, India is one of the most culturally and genetically diverse countries in the world.

26 Jun 2025

Harnessing saliva for precision medicine and early disease diagnosis

A research team led by the University of the Basque Country (Euskal Herriko Unibertsitatea, EHU) has identified hundreds of molecular markers in saliva that could reveal the risk of a person developing major diseases such as cancer, cardiovascular diseases, diabetes and neurodegenerative diseases.

26 Jun 2025