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Breakthrough Omicron BA.1/BA.2 infections in the triple-vaccinated linked to broad-based immunity

A new study looked at the whole spectrum of immunological reactions raised by spike and non-spike antigens following Omicron BA.1/BA.2 infections in such individuals, both with and without prior SARS-CoV-2 infection.

1 Feb 2023

New nanomedicine delivery system offers some hope for treating peritoneal cancer

Peritoneal cancer is difficult to treat and has a poor survival prognosis. But a new and effective nanomedicine delivery system is offering some hope.

31 Jan 2023

A machine-learning approach to identify asthma subtypes based on molecular signatures

Researchers determine whether protein expression in nasal fluid samples could assist in the diagnosis of severe asthma subtypes.

31 Jan 2023

Actin influences cancer metastases in many ways

Metastases occur when cancer cells leave a primary tumor and spread throughout the body. For this, they have to break connections with neighboring cells and migrate to other tissues.

31 Jan 2023

The impact of common viral infections on blood-brain barrier function and insulin sensitivity

A new study discusses the impact of several human viruses on blood-brain barrier function and insulin sensitivity.

31 Jan 2023

Cornell research provides new insight into chemotherapy agent's effect on DNA

New Cornell research is providing a fresh view into the ways a common chemotherapy agent, etoposide, stalls and poisons the essential enzymes that allow cancer cells to flourish.

30 Jan 2023

New candidate molecule could become an effective non-hormonal male contraceptive

Despite birth control existing for decades, almost none of the options specifically target sperm cells. Researchers are now developing approaches that target testosterone or otherwise interrupt the sperm's ability to fertilize an egg, yet these may not work for everyone.

30 Jan 2023

$1 million grant will help University of Utah chemists to speed up the drug development process

Michael Grünwald, Ryan Looper and Rodrigo Noriega, of the University of Utah Department of Chemistry, received a $1 million grant from the W.M. Keck Foundation funding studies of currently unpredictable aspects of the process of crystallization.

30 Jan 2023

Scientists Develop a Cancer Vaccine to Simultaneously Kill and Prevent Brain Cancer

Dual-action cell therapy engineered to eliminate established tumors and train the immune system to eradicate primary tumor and prevent cancer’s recurrence.

30 Jan 2023

NUS scientists breathe new life into an existing drug to fight T-cell acute lymphoblastic leukemia

A team of researchers from the Cancer Science Institute of Singapore at the National University of Singapore, led by Associate Professor Takaomi Sanda and Dr Lim Fang Qi, has breathed new life into an existing drug—combatting a type of blood cancer called T-cell acute lymphoblastic leukemia, or T-ALL.

30 Jan 2023

Using systems biology research to alter the properties of carcinogenic cells in the lungs

KAIST (President Kwang Hyung Lee) announced on January 30th that a research team led by Professor Kwang-Hyun Cho from the Department of Bio and Brain Engineering succeeded in using systems biology research to change the properties of carcinogenic cells in the lungs and eliminate both drug resistance and their ability to proliferate out to other areas of the body.

29 Jan 2023

Keto diet as a PCOS treatment

A recent study explores the role of the ketogenic diet in the treatment of polycystic ovarian syndrome.

29 Jan 2023

Biology underlying pair bonding and parenting may not be dictated by oxytocin receptors, study shows

Turning a decades-old dogma on its head, new research from scientists at UC San Francisco and Stanford Medicine shows that the receptor for oxytocin, a hormone considered essential to forming social bonds, may not play the critical role that scientists have assigned to it for the past 30 years.

27 Jan 2023

A high-throughput screening assay for small molecule inhibitors of the antigen aminopeptidase ERAP1

The January 2023 issue of SLAS Discovery contains a collection of four full-length articles and one technical brief covering cancer research, high-throughput screening (HTS) assay development and other drug discovery exploration.

27 Jan 2023

Protein adduction and p53 tumor suppressor inhibition

Researchers assessed the impact of protein adduction on p53 tumor suppressor inhibition.

27 Jan 2023

Single drop of blood can be used to measure thousands of molecules

Researchers at Stanford Medicine have shown they can measure thousands of molecules — some of which are signals of health — from a single drop of blood.

25 Jan 2023

Targeting newly discovered signaling pathway could boost the potency of cancer therapeutics

Cells zealously protect the integrity of their genomes, because damage can lead to cancer or cell death. The genome - a cell's complete set of DNA - is most vulnerable while it is being duplicated before a cell divides. Cancer cells constantly are dividing, so their genomes are constantly in jeopardy.

24 Jan 2023

Molecule News and Research

Breakthrough Omicron BA.1/BA.2 infections in the triple-vaccinated linked to broad-based immunity

New nanomedicine delivery system offers some hope for treating peritoneal cancer

A machine-learning approach to identify asthma subtypes based on molecular signatures

Actin influences cancer metastases in many ways

The impact of common viral infections on blood-brain barrier function and insulin sensitivity

Cornell research provides new insight into chemotherapy agent's effect on DNA

New candidate molecule could become an effective non-hormonal male contraceptive

$1 million grant will help University of Utah chemists to speed up the drug development process

Scientists Develop a Cancer Vaccine to Simultaneously Kill and Prevent Brain Cancer

NUS scientists breathe new life into an existing drug to fight T-cell acute lymphoblastic leukemia

Using systems biology research to alter the properties of carcinogenic cells in the lungs

Keto diet as a PCOS treatment

Biology underlying pair bonding and parenting may not be dictated by oxytocin receptors, study shows

A high-throughput screening assay for small molecule inhibitors of the antigen aminopeptidase ERAP1

Protein adduction and p53 tumor suppressor inhibition

Single drop of blood can be used to measure thousands of molecules

Targeting newly discovered signaling pathway could boost the potency of cancer therapeutics

Study reveals sex differences in response to drugs targeting tauopathies

Mitochondrial dysfunction and endothelial impairment linked to many cardiovascular diseases

DNA sequencing method detects where and how small molecule drugs interact with the targeted genome

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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