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Clinical benefit of new cancer therapies may justify the expensive price

Researchers from the University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences, selected to estimate the cost-effectiveness of the newly approved CAR-T therapies, have found the clinical benefit may justify the expensive price.

20 Dec 2017

Scientists find sperm as potential drug carrier to treat gynecological conditions

Delivering drugs specifically to cancer cells is one approach researchers are taking to minimize treatment side effects. Stem cells, bacteria and other carriers have been tested as tiny delivery vehicles.

20 Dec 2017

Unmarried heart disease patients have higher risk of death

Compared to married heart disease patients, being unmarried was associated with a higher risk of dying, according to new research in Journal of the American Heart Association, the Open Access Journal of the American Heart Association/American Stroke Association.

20 Dec 2017

KU researchers win $10.8 NIH grant to study cancer, neurological disorders, lung and heart diseases

The University of Kansas' Center for Molecular Analysis of Disease Pathways, a National Institutes of Health Center of Biomedical Research Excellence, recently earned a second phase of grant funding in the amount of $10.8 million for an additional five years.

19 Dec 2017

UGR study paves way for development of better analgesics to treat joint pain

Researchers from the University of Granada have led a novel study in mice which shows that neurons mediating joint pain are different from those mediating cutaneous pain.

19 Dec 2017

Drug industry spent millions to squelch talk about high drug prices

Facing bipartisan hostility over high drug prices in an election year, the pharma industry's biggest trade group boosted revenue by nearly a fourth last year and spread the millions collected among hundreds of lobbyists, politicians and patient groups, new filings show.

19 Dec 2017

C-Path receives FDA’s clinical outcome assessment qualification for SMDDS

Critical Path Institute's Patient-Reported Outcome Consortium announces its first clinical outcome assessment qualification from the US Food and Drug Administration for the Symptoms of Major Depressive Disorder Scale.

18 Dec 2017

Children who experience abuse, adversity more likely to develop cardiovascular diseases in adulthood

Children and teens who are abused, witness violence, are bullied or face other adversities are more likely to develop cardiovascular diseases in adulthood, according to a new scientific statement by the American Heart Association published in the Association's journal Circulation.

18 Dec 2017

Scientists use nanoparticles to fight Mucoviscidosis

Scientists of the Friedrich Schiller University Jena, Germany succeeded in developing an efficient method to treat Mucoviscidosis. Crucial are nanoparticles that transport the antibiotics more efficiently to their destination.

15 Dec 2017

Exascale supercomputers may discover new, cheaper drugs in future

Can you imagine a future where an exascale computer discovers new drugs faster, cheaper and with lower failure rates than today?

14 Dec 2017

IPM begins first clinical trial of vaginal rings to prevent HIV in women

The nonprofit International Partnership for Microbicides announced today the start of the first clinical trial of vaginal rings designed to slowly release the antiretroviral drug dapivirine over three months to prevent HIV in women.

13 Dec 2017

Survey shows prevalence of diarrhea in people living with HIV

Napo Pharmaceuticals, Inc., a human health company developing and commercializing novel gastrointestinal prescription products from plants used traditionally in rainforest areas, and a wholly-owned subsidiary of Jaguar Health, Inc., today released the results of a survey of 350 people living with HIV and AIDS on "Talking to Your Doctor About Symptoms".

13 Dec 2017

New treatments may soon transform lives of people with hearing loss

Charity Action on Hearing Loss has released its latest update on the progress that it is making to accelerate the development of technology and treatments for people living with deafness, tinnitus and hearing loss.

13 Dec 2017

Tapeworm drug could provide new hope for patients with Parkinson's disease

Researchers at Cardiff University, in collaboration with the University of Dundee, have identified a drug molecule within a medicine used to treat tapeworm infections which could lead to new treatments for patients with Parkinson's disease.

12 Dec 2017

Experts tell Congress how to cut drug prices

The nation's most influential science advisory group will tell Congress today that the U.S. pharmaceutical market is not sustainable and needs to change.

12 Dec 2017

Researchers find new role for SHARPIN protein in melanoma growth

Researchers at Sanford Burnham Prebys Medical Discovery and the Technion in Israel have found a new role for the SHARPIN protein. In addition to being one of three proteins in the linear ubiquitin chain assembly complex, regulating NFκB and other inflammatory molecules, SHARPIN modulates PRMT5, an epigenetic master switch that controls several proteins linked to melanoma. The research was published in The Journal of Clinical Investigation.

12 Dec 2017

Huntington's disease drug clears initial hurdles - raising hopes

Huntington’s disease is a genetic disorder that affects the brain progressively and has no known cure till date. In a breakthrough, the first drug that can target and reduce the cause behind this dreaded disease has been found to be effective, safe and well tolerated in a human clinical trial that was conducted by UCL scientists.

11 Dec 2017

Study: Combination targeted therapy has high response rates in AML patients

Initial findings from a multi-national open-label phase Ib study of inhibitory drug therapy for relapsed or refractory acute myeloid leukemia (AML) have demonstrated a complete response in up to 50 percent patients say researchers at The University of Texas MD Anderson Cancer Center.

11 Dec 2017

Butler Hospital launches international Alzheimer's disease prevention study

The Memory and Aging Program at Butler Hospital, a member of Care New England and a major teaching affiliate of The Warren Alpert Medical School of Brown University, enrolled one of the initial participants in an international Alzheimer's disease (AD) prevention study.

11 Dec 2017

LSUHealthNO breakthrough may pave way for advances in obesity-related diseases

For the first time, researchers led by Frank Lau, MD, Assistant Professor of Clinical Surgery at LSU Health New Orleans, have successfully kept white fat tissue alive outside of the body for up to eight weeks.

11 Dec 2017