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Study: New gene therapy safe, effective for patients with hemophilia B

A multi-year, ongoing study suggests that a new kind of gene therapy for hemophilia B could be safe and effective for human patients. Published in the journal Science Translational Medicine, the research showed that a reprogrammed retrovirus could successfully transfer new factor IX (clotting) genes into animals with hemophilia B to dramatically decrease spontaneous bleeding.

12 Mar 2015

Finding could lead to more effective, less invasive treatment for 'bubble boy' disease

For infants with severe combined immunodeficiency (SCID), something as simple as a common cold or ear infection can be fatal. Born with an incomplete immune system, kids who have SCID--also known as "bubble boy" or "bubble baby" disease--can't fight off even the mildest of germs.

12 Mar 2015

Penn researcher named a recipient of 2015 Paul Ehrlich and Ludwig Darmstaedter Prize

University of Pennsylvania cancer and HIV expert Carl June, MD, has been named one of two recipients of the 2015 Paul Ehrlich and Ludwig Darmstaedter Prize for his outstanding work in cancer immunotherapy. Since 1952, the Paul Ehrlich and Ludwig Darmstaedter Prize has been awarded to scientists who have made great advancements in the fields in which Paul Ehrlich worked, in particular immunology, cancer research, microbiology, and chemotherapy.

12 Mar 2015

Melbourne researchers develop new genome editing technology to kill blood cancer cells

Melbourne researchers have developed a new genome editing technology that can target and kill blood cancer cells with high accuracy.

12 Mar 2015

Homewood Health introduces ad campaign to create awareness of new outpatient clinic

Homewood Health Inc. has launched a bold new advertising campaign in the southern Alberta market to create awareness of its first new mental health and addiction treatment clinic, The Homewood Clinic, located in southwest Calgary.

12 Mar 2015

Neuralstem reports top line data from NSI-566 Phase II trial for treatment of ALS

Neuralstem, Inc. announced top line data from the Phase II trial of NSI-566 spinal cord-derived neural stem cells under development for the treatment of amyotrophic lateral sclerosis (ALS). The study met primary safety endpoints. The maximum tolerated dose of 16 million transplanted cells and the surgery was well tolerated.

12 Mar 2015

Oxis Biotech executes licensing agreement with MCIT for development of antibody-drug conjugates

Oxis Biotech, Inc., a wholly owned subsidiary of Oxis International, Inc., announced today the execution of a definitive licensing and development agreement with MultiCell Immunotherapeutics, Inc. concerning the development of certain antibody-drug conjugates (ADCs).

12 Mar 2015

Washington University researchers develop way to apply light-based therapy to reach deep tumors

Light long has been used to treat cancer. But phototherapy is only effective where light easily can reach, limiting its use to cancers of the skin and in areas accessible with an endoscope, such as the gastrointestinal tract.

12 Mar 2015

Fracture prevention project could help save millions

Bone fractures affect millions of people across the UK with 1 in 2 women and 1 in 5 men over the age of 50 suffering from them . The cost of fragility fractures place a substantial economic burden on the health and social care system with the costs of fragility fractures in the region of £2.3bn .

12 Mar 2015

Study finding suggests importance of individually-tailored treatment for depression

The most commonly used treatment for the over 14 million Americans who suffer from Major Depressive Disorder is anti-depressant medication. While such medications bring relief to many, current research suggests that one size may not fit all when it comes to treating depression.

12 Mar 2015

UTHealth remotely enrolls patients into acute stroke clinical trial with telemedicine method

For the first time in the world, researchers at The University of Texas Health Science Center at Houston were able to enroll patients at other hospitals into an acute stroke clinical trial.

12 Mar 2015

Existing epilepsy drug reverses aMCI in elderly patients at risk for Alzheimer's disease

A novel therapeutic approach for an existing drug reverses a condition in elderly patients who are at high risk for dementia due to Alzheimer's disease, researchers at Johns Hopkins University found.

12 Mar 2015

Tetanus booster shot enhances effect of vaccine therapy for lethal brain tumors

An innovative approach using a tetanus booster to prime the immune system enhances the effect of a vaccine therapy for lethal brain tumors, dramatically improving patient survival, according to a study led by Duke Cancer Institute researchers.

12 Mar 2015

Early mobility therapy improves outcomes of patients with acute respiratory distress syndrome

Acute respiratory distress syndrome (ARDS) is a life-threatening lung condition that affects approximately 200,000 people a year in the United States and has a higher mortality rate than breast and prostate cancer combined. The condition most often occurs in people who are critically ill or who have significant injuries; those who do survive it often experience profound skeletal muscle weakness.

12 Mar 2015

Ablative Solutions named recipient of CRT's Top Cardiovascular Innovation Award

Ablative Solutions, Inc., a venture-backed, privately-held clinical stage company headquartered in Kalamazoo, MI, with offices in Menlo Park, CA, announced today that it was the recipient of a "Top Cardiovascular Innovation Award" from Cardiovascular Research Technologies for the Peregrine System.

12 Mar 2015

Deutsches Ärzteblatt International's current issue features two articles on geriatric medicine

Very old persons often have chronic problems, such as physical immobility, unsteady gait, and mental impairments. In such patients, these risks have to be considered and their treatments adapted accordingly. Deutsches Ärzteblatt International in its current issue introduces two original articles on the subject of geriatric medicine.

12 Mar 2015

Patients who receive definitive CCRT treatment for stage III NSCLC have longer overall survival

Patients treated with definitive concurrent chemotherapy and radiation therapy (CCRT) for stage III non-small cell lung cancer (NSCLC) have longer overall survival when treated by highly experienced facilities, whether or not they are academic or community cancer centers.

12 Mar 2015

Researchers take important step in repairing the cerebral cortex of adult mouse

A team led by Afsaneh Gaillard (Inserm Unit 1084, Experimental and Clinical Neurosciences Laboratory, University of Poitiers), in collaboration with the Institute of Interdisciplinary Research in Human and Molecular Biology (IRIBHM) in Brussels, has just taken an important step in the area of cell therapy: repairing the cerebral cortex of the adult mouse using a graft of cortical neurons derived from embryonic stem cells.

12 Mar 2015

New study shows how presenilin gene mutations may lead to familial Alzheimer's disease

Mutations in the presenilin-1 gene are the most common cause of inherited, early-onset forms of Alzheimer's disease. In a new study, published in Neuron, scientists replaced the normal mouse presenilin-1 gene with Alzheimer's-causing forms of the human gene to discover how these genetic changes may lead to the disorder.

12 Mar 2015

Glucocorticoid therapies promote functional recovery of blood-brain barrier after blast injury

Barclay Morrison III, associate professor of biomedical engineering at Columbia Engineering, has led the first study to determine underlying biological mechanisms that promote functional recovery of the blood-brain barrier (BBB) after blast injury. The research demonstrates that treatment with the glucocorticoid, dexamethasone, after primary blast injury promotes rapid recovery of an in vitro model of the BBB, a highly restrictive semi-permeable barrier whose primary function is to maintain the brain's microenvironment and protect it from potentially toxic substances.

12 Mar 2015

Therapy News and Research

Study: New gene therapy safe, effective for patients with hemophilia B

Finding could lead to more effective, less invasive treatment for 'bubble boy' disease

Penn researcher named a recipient of 2015 Paul Ehrlich and Ludwig Darmstaedter Prize

Melbourne researchers develop new genome editing technology to kill blood cancer cells

Homewood Health introduces ad campaign to create awareness of new outpatient clinic

Neuralstem reports top line data from NSI-566 Phase II trial for treatment of ALS

Oxis Biotech executes licensing agreement with MCIT for development of antibody-drug conjugates

Washington University researchers develop way to apply light-based therapy to reach deep tumors

Fracture prevention project could help save millions

Study finding suggests importance of individually-tailored treatment for depression

UTHealth remotely enrolls patients into acute stroke clinical trial with telemedicine method

Existing epilepsy drug reverses aMCI in elderly patients at risk for Alzheimer's disease

Tetanus booster shot enhances effect of vaccine therapy for lethal brain tumors

Early mobility therapy improves outcomes of patients with acute respiratory distress syndrome

Ablative Solutions named recipient of CRT's Top Cardiovascular Innovation Award

Deutsches Ärzteblatt International's current issue features two articles on geriatric medicine

Patients who receive definitive CCRT treatment for stage III NSCLC have longer overall survival

Researchers take important step in repairing the cerebral cortex of adult mouse

New study shows how presenilin gene mutations may lead to familial Alzheimer's disease

Glucocorticoid therapies promote functional recovery of blood-brain barrier after blast injury

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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