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Gender and personality significantly affect cancer-related pain management in elderly patients

With 75% of cancer patients in the UK over 60, and the costs of innovative drugs soaring, how to best identify and hopefully manage cancer-related pain in the elderly is a key issue. A new study published in the Journal of Gender Studies looks into this complex matter and, in claiming gender and personality significantly affect the experience of suffering, questions a 'one size fits it all' approach to pain management.

12 Jun 2015

Researchers working on new system that can detect patient's antibiotic resistance in 30 minutes

A new device being developed by medical experts will transform the time it takes to detect antibiotic resistance in patients from several days to just half an hour.

12 Jun 2015

New cholesterol-lowering drugs have potential to prevent heart attack, stroke

On the brink of FDA approval is a new class of cholesterol-lowering drugs that have the potential to change the landscape in the prevention of heart attack and stroke.

12 Jun 2015

Researchers show how a new drug speeds tissue regeneration in animal models

The concept sounds like the stuff of science fiction: take a pill, and suddenly new tissues grow to replace damaged ones. Researchers at Case Western Reserve and UT Southwestern Medical Center this week announced that they have taken significant steps toward turning this once-improbable idea into a vivid reality.

12 Jun 2015

Researchers uncover how Gram-negative bacteria can trigger immune system reaction

Researchers at the University of Toronto have uncovered how Gram-negative bacteria -- a broad class of bugs that cause diseases ranging from gonorrhea to diarrhea and pneumonia -- can trigger a reaction from our immune system. This discovery could lead to new therapies and treatments that use the immune system to fight infections instead of antibiotics.

12 Jun 2015

Weill Cornell scientists reveal how XBP1 gene can trigger immune responses against ovarian tumors

Ovarian cancer shuts down immune system cells that would otherwise act as a first line of defense against the deadly tumor, Weill Cornell Medical College scientists report today. But a therapy that restores the cells' disease-fighting abilities could provide a powerful new strategy to attack the cancer, which kills more than 14,000 women each year.

12 Jun 2015

NSAIDs significantly inhibit ovulation in women with mild musculoskeletal pain

The results of a study presented today at the European League Against Rheumatism Annual Congress (EULAR 2015) show that diclofenac, naproxen and etoricoxib significantly inhibit ovulation in women with mild musculoskeletal pain. Of the women receiving NSAIDs, only 6.3 percent (diclofenac), 25 percent (naproxen) and 27.3 percent (etoricoxib) ovulated, compared with 100 percent of the control group.

12 Jun 2015

Certain ARID1a mutations sensitize some tumors to PARP inhibitor drugs

Mutations in ARID1a, which are common in many cancer types, disrupt DNA damage repair in cancer cells, allowing the cancer to progress. This gene may also be an Achilles' heel when treating certain tumors, according to a team of researchers at The University of Texas MD Anderson Cancer Center.

12 Jun 2015

Discovery may help scientists attack the root of deadliest brain tumors

Some brain tumors are notoriously difficult to treat. Whether surgically removed, zapped by radiation or infiltrated by chemotherapy drugs, they find a way to return. The ability of many brain tumors to regenerate can be traced to cancer stem cells that evade treatment and spur the growth of new tumor cells.

11 Jun 2015

USC Stem Cell scientist named 2015 Pew-Stewart scholar for cancer research

USC Stem Cell researcher Min Yu, MD, PhD, is one of five early-career scientists to be named a 2015 Pew-Stewart scholar for cancer research. As part of this honor, she will receive $240,000 over four years to advance the understanding of metastatic breast cancer.

11 Jun 2015

AfBPM launches new educational tool to help assess, reduce medication abuse in home

The Alliance for Balanced Pain Management today launched a new educational tool – "Are You the Only One Taking Your Medicine?" – that consumers and health care providers can use to assess whether a home is at risk for medication misuse, abuse or diversion.

11 Jun 2015

Isis Pharmaceuticals provides update on ISIS-SMN Rx Phase 2 clinical study in infants with Type I SMA

Isis Pharmaceuticals, Inc. today provided an update on its ongoing open-label Phase 2 clinical study of ISIS-SMN Rx in infants with Type I spinal muscular atrophy (SMA).

11 Jun 2015

Common antibiotic azithromycin effectively kills many multidrug-resistant bacteria

Contrary to current medical dogma, researchers at University of California, San Diego School of Medicine and Skaggs School of Pharmacy and Pharmaceutical Sciences report that the common antibiotic azithromycin kills many multidrug-resistant bacteria very effectively — when tested under conditions that closely resemble the human body and its natural antimicrobial factors.

11 Jun 2015

Only one in five patients qualified for free 'midlife MOT' takes NHS heart health check-ups

Only one in five patients eligible for a free "midlife MOT" on the NHS took up the offer in the first four years of the programme.

11 Jun 2015

Proton pump inhibitors linked to increased risk of heart attack

People who use proton pump inhibitors (PPIs) are up to 21% more likely to experience a heart attack than people who do not use the antacids, according to researchers from Stanford University, California.

11 Jun 2015

SQUIRE phase III study shows necitumumab improves median overall survival in squamous NSCLC patients

This week, Lancet Oncology reports results of a 1,093-person phase III clinical trial of the drug necitumumab (IMC-11F8) combined with chemotherapies gemcitabine and cisplatin against stage IV squamous non-small cell lung cancer. With addition of necitumumab, median overall survival was 11.5 months compared with median survival of 9.9 months with the two chemotherapies alone.

11 Jun 2015

Protein-signaling process accelerates work of gene mutation linked to common form of adult leukemia

In preliminary experiments with mice and lab-grown cells, Johns Hopkins Kimmel Cancer Center scientists have found that a protein-signaling process accelerates the work of the gene most frequently mutated in a common form of adult leukemia and is likely necessary to bring about the full-blown disease.

11 Jun 2015

Scientists and clinicians from across the UK come together to address treatment of brain tumors

In an exciting step forward to finding a cure for brain tumours, which kill more children and adults under the age of 40 than any other cancer, the national charity Brain Tumour Research brought together a group of leading brain tumour scientists and clinicians to help accelerate vital research into this devastating disease.

11 Jun 2015

New insights on crop-rotation resistant rootworms may help develop sustainable agricultural practices

After decades of effort, scientists are finally figuring out how insects develop resistance to environmentally friendly farming practices - such as crop rotation - that are designed to kill them. The researchers say their insights will help develop more sustainable agricultural practices.

11 Jun 2015

Ixekizumab drug shows quick and extensive improvements in patients with psoriasis

A University of Manchester led trial of a new psoriasis drug has resulted in 40 percent of people showing a complete clearance of psoriatic plaques after 12 weeks of treatment and over 90 percent showing improvement.

11 Jun 2015

Drugs News and Research

Gender and personality significantly affect cancer-related pain management in elderly patients

Researchers working on new system that can detect patient's antibiotic resistance in 30 minutes

New cholesterol-lowering drugs have potential to prevent heart attack, stroke

Researchers show how a new drug speeds tissue regeneration in animal models

Researchers uncover how Gram-negative bacteria can trigger immune system reaction

Weill Cornell scientists reveal how XBP1 gene can trigger immune responses against ovarian tumors

NSAIDs significantly inhibit ovulation in women with mild musculoskeletal pain

Certain ARID1a mutations sensitize some tumors to PARP inhibitor drugs

Discovery may help scientists attack the root of deadliest brain tumors

USC Stem Cell scientist named 2015 Pew-Stewart scholar for cancer research

AfBPM launches new educational tool to help assess, reduce medication abuse in home

Isis Pharmaceuticals provides update on ISIS-SMN Rx Phase 2 clinical study in infants with Type I SMA

Common antibiotic azithromycin effectively kills many multidrug-resistant bacteria

Only one in five patients qualified for free 'midlife MOT' takes NHS heart health check-ups

Proton pump inhibitors linked to increased risk of heart attack

SQUIRE phase III study shows necitumumab improves median overall survival in squamous NSCLC patients

Protein-signaling process accelerates work of gene mutation linked to common form of adult leukemia

Scientists and clinicians from across the UK come together to address treatment of brain tumors

New insights on crop-rotation resistant rootworms may help develop sustainable agricultural practices

Ixekizumab drug shows quick and extensive improvements in patients with psoriasis

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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