Immune System News and Research

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Living Cell Technologies announces results for treating Huntington's disease

Living Cell Technologies announced pre-clinical results today showing its brain protection product, NeurotrophinCell (NtCell) produces a marked reduction in the size of brain lesions in a Huntington's disease (HD) model.

2 Aug 2005

Discovery that oxidative stress from pollen is as important as antigen exposure could lead to new therapies

For a person with allergies or asthma, breathing in pollen can be a very bad thing. Within minutes of inhalation by someone sensitive to their effects, these tiny particles can trigger severe inflammation of the respiratory passages, producing uncontrollable sneezing, coughing, or extreme shortness of breath -- symptoms agonizingly familiar to those who suffer from allergy and asthma attacks.

1 Aug 2005

Inhibitors of cellular enzymes could be developed for SARS treatment

Researchers from the University of Pennsylvania School of Medicine have found that inhibitors of an enzyme called cathepsin L prevent the SARS (severe acute respiratory syndrome) virus from entering target cells. SARS is caused by an emergent coronavirus. There is no effective treatment at this time.

1 Aug 2005

New understanding of cell movement may yield ways to brake cancer's spread

From birth until death, our cells migrate: nerve cells make their vital connections, embryonic cells move to the proper places to form organs, immune cells zero in to destroy pathogenic organisms, and cancer cells metastasize, spreading deadly disease through the body. Scientists studying these migrations didn't know how cells determined where to go. Until now.

1 Aug 2005

New recommendations can help medical arms of the military meet their mission

As reported last December in the New England Journal of Medicine, the U.S. military's on-the-ground surgical strategy now aims at "damage control, not definitive repair, unless it can be done quickly."

1 Aug 2005

Cannabis drugs may benefit those with bowel disease

UK scientists say they believe that patients with inflammatory bowel disease may benefit from cannabis-based drugs.

1 Aug 2005

Heparinase I is not a suitable replacement for protamine

The results of an international clinical trial led by Duke University Medical Center researchers has shown that a new drug is not a suitable replacement for protamine, a drug that has been used for more than 40 years after coronary artery bypass surgery to return thinned blood to its normal state.

1 Aug 2005

Pseudomonas aeruginosa has broken the immune system's code

The human opportunistic pathogen, Pseudomonas aeruginosa, has broken the immune system's code, report researchers from the University of Chicago, enabling the bacteria to recognize when its host is most vulnerable and to launch an attack before the weakened host can muster its defenses.

1 Aug 2005

Two studies reveal how plague disables immune system

Two studies by researchers at the University of Chicago show how the bacteria that cause the plague manage to outsmart the immune system and how, by slightly altering one of the microbe's tools, the researchers produced what may be the first safe and effective vaccine.

1 Aug 2005

Stress delays wound healing

Wound healing is slow when an animal is stressed, but extra oxygen almost completely reverses the effect, according to researchers at the University of Illinois at Chicago.

28 Jul 2005

Anti-inflammatory function of Alzheimer's disease drugs revealed

The mechanism in anti-Alzheimer's disease drugs that inhibits the production of a destructive, inflammation-causing protein in the brain has been revealed by researchers at the Hebrew university of Jerusalem.

28 Jul 2005

Echinacea little use in relieving colds

According to a new study by the University of Virginia School of Medicine, taking the the herbal remedy Echinacea, to relieve the symptoms of the common cold, is a waste of time and offers no more relief than a placebo.

28 Jul 2005

Carbon monoxide could turn out to be a life-saver for patients recovering from organ transplants

Carbon monoxide, a poisonous gas that kills thousands of Americans every year, could turn out to be a life-saver for patients recovering from organ transplants, strokes or heart attacks, according to new research from the University of Michigan Cardiovascular Center.

28 Jul 2005

Participants in the gene therapy market discover new ways to improve clinical efficiency and generate revenue

The gene therapy market has had limited success with products during the clinical development process. Due to toxicological complications and poor therapy efficacy, healthcare authorities have suspended several gene therapy trials worldwide.

28 Jul 2005

Cancer biology, pharmacology and engineering combine to create cancer smart bomb

Imagine a cancer drug that can burrow into a tumor, seal the exits and detonate a lethal dose of anti-cancer toxins, all while leaving healthy cells unscathed.

27 Jul 2005

Specialized immune-system B cells play dual role in triggering both kinds of immunity - innate and acquired

A specialized subpopulation of the antibody-producing B cells of the immune system plays a "double-barreled" role in triggering both kinds of immunity - innate and acquired, Duke University Medical Center immunologists have discovered.

26 Jul 2005

Research sets foundation for new generation of vaccines for HIV, influenza

Scientists have taken a major step toward the goal of altering viruses, bacteria and tumor cells so that they demand attention from immune cells designed to destroy them.

26 Jul 2005

Cancer vaccine combined with hormone-deprivation therapy can help patients with recurrence of prostate cancer

A new study finds that a cancer vaccine combined with hormone-deprivation therapy can help patients with recurrence of prostate cancer. The results of this clinical trial, led by scientists at the National Cancer Institute (NCI), part of the National Institutes of Health, appear in the August 2005 issue of the Journal of Urology.

26 Jul 2005

Loyola researchers hope that zoledronic acid will be effective and safe for patients with inflammatory bowel diseases (IBD)

Researchers at the Osteoporosis and Metabolic Bone Disease Center and the Division of Gastroenterology at Loyola University Health System are studying a once-yearly, 15-minute infusion of an intravenous (IV) medication in patients with osteopenia (low bone mass) and inflammatory bowel diseases (IBD) that, if proven effective, may be considered the standard of treatment.

26 Jul 2005

First large-scale effort to sequence the flu genome

Multiple strains of the flu virus, circulating in a population at the same time, can reshuffle their genes and create a new virus, one capable of infecting many more people, according to a new study in the open-access journal PLoS Biology.

26 Jul 2005

Immune System News and Research

Living Cell Technologies announces results for treating Huntington's disease

Discovery that oxidative stress from pollen is as important as antigen exposure could lead to new therapies

Inhibitors of cellular enzymes could be developed for SARS treatment

New understanding of cell movement may yield ways to brake cancer's spread

New recommendations can help medical arms of the military meet their mission

Cannabis drugs may benefit those with bowel disease

Heparinase I is not a suitable replacement for protamine

Pseudomonas aeruginosa has broken the immune system's code

Two studies reveal how plague disables immune system

Stress delays wound healing

Anti-inflammatory function of Alzheimer's disease drugs revealed

Echinacea little use in relieving colds

Carbon monoxide could turn out to be a life-saver for patients recovering from organ transplants

Participants in the gene therapy market discover new ways to improve clinical efficiency and generate revenue

Cancer biology, pharmacology and engineering combine to create cancer smart bomb

Specialized immune-system B cells play dual role in triggering both kinds of immunity - innate and acquired

Research sets foundation for new generation of vaccines for HIV, influenza

Cancer vaccine combined with hormone-deprivation therapy can help patients with recurrence of prostate cancer

Loyola researchers hope that zoledronic acid will be effective and safe for patients with inflammatory bowel diseases (IBD)

First large-scale effort to sequence the flu genome

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