Genetic News and Research

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What RFK Jr. isn’t talking about: How to make vaccines safer

Within an hour of receiving a covid vaccination in November 2020, Utah preschool teacher Brianne Dressen felt pins and needles through her arms and legs.

25 Jun 2025

Fusion genes found to be pivotal players in cancer development

Fusion genes, arising from abnormal chromosomal rearrangements, are gaining recognition as pivotal players in cancer development. These genetic alterations result in the creation of hybrid genes with altered functions, often driving tumor progression.

25 Jun 2025

Scientists use base editing to repair mitochondrial DNA mutations

In a step toward treating mitochondrial diseases, researchers in the Netherlands have successfully edited harmful mutations in mitochondrial DNA using a genetic tool known as a base editor.

25 Jun 2025

How a novel reaction in E. coli helps recycle plastic into paracetamol

Researchers have demonstrated that E. coli can perform a biocompatible Lossen rearrangement, enabling phosphate-catalysed conversion of synthetic substrates into valuable compounds. This approach allows engineered bacteria to upcycle PET plastic waste into paracetamol, highlighting a novel intersection of chemistry and biotechnology.

24 Jun 2025

Once-monthly obesity injection shows double-digit weight loss in major clinical trial

Researchers found that once-monthly maridebart cafraglutide led to substantial weight loss and improved glycemic control in adults with obesity, with or without diabetes, in a phase 2 randomized trial. The drug demonstrated an acceptable safety profile and supports further study in phase 3 trials.

24 Jun 2025

Mayo Clinic researchers discover how ovarian cancer may begin

Little is known about what causes ovarian cancer, and there is no way to detect it early yet. About 75% of the time when someone is diagnosed with ovarian cancer, it has already progressed to stage 3 or stage 4, which means it has spread to other parts of the body.

24 Jun 2025

UNIGE scientists uncover two key proteins that regulate chromatin remodelling

Cells depend on the precise reading of DNA sequences to function correctly. This process, known as gene expression, determines which genetic instructions are activated.

24 Jun 2025

Genetic markers show promise in predicting mood disorder treatment outcomes

In a comprehensive Genomic Press Thought Leaders Invited Review, researchers have synthesized findings from dozens of studies examining how genetic markers for mood disorders influence treatment outcomes and clinical features across major psychiatric conditions.

24 Jun 2025

Study identifies potential way to slow or block progression of age-related macular degeneration

A new study from Washington University School of Medicine in St. Louis identifies a possible way to slow or block progression of age-related macular degeneration, a leading cause of blindness in people over age 50.

24 Jun 2025

Excess trace metal levels may trigger gestational diabetes

Excess micronutrients in early pregnancy may raise gestational diabetes risks. Study links essential metal levels to GDM onset, urging a rethink on supplements.

24 Jun 2025

New genomic test predicts chemotherapy resistance in cancer patients

Chemotherapy seeks to destroy tumor cells and has been a standard treatment for cancer for decades.

24 Jun 2025

Genetically engineered skin grafts help heal chronic wounds in patients with epidermolysis bullosa

Skin grafts genetically engineered from a patient's own cells can heal persistent wounds in people with an extremely painful dermatologic disease, a Stanford Medicine-led clinical trial has shown.

23 Jun 2025

Mediterranean diet boosts sperm health while ultra-processed foods lower fertility, study finds

Adherence to the Mediterranean diet is linked to improved sperm parameters in men, while high intake of ultra-processed foods is associated with poorer semen quality. These associations are strongest in men with normal FSH levels, suggesting dietary patterns may influence male fertility.

23 Jun 2025

Pregnancy complications linked to higher long-term stroke risk in women

Women who experience complications during pregnancy face a higher risk of stroke in the following decades according to research published in the European Heart Journal today (Tuesday).

23 Jun 2025

Scientists warn of rising threat as poultry disease shows signs of jumping to humans

Avian Intestinal Spirochaetosis (AIS) is a chronic, underreported poultry disease caused by Brachyspira spp., with rising concern over its zoonotic risk to humans. This review highlights key challenges in diagnosis, antibiotic resistance, transmission, and the urgent need for improved surveillance and new prevention strategies.

23 Jun 2025

Newly evolved genes reveal surprising role in human cell division

Every day, our bodies perform around 330 billion cell divisions to keep us alive and functioning. These divisions rely on the cell cycle, which has been in place since the earliest bacteria.

23 Jun 2025

Next generation CAR-T cells push the boundaries of lymphoma treatment

CAR-T cells, which are genetically programmed to specifically recognize and kill target cells, have altered the therapeutic landscape of lymphoma.

23 Jun 2025

New imaging breakthrough sheds light on brain communication pathways

For the first time, scientists using cryo-electron microscopy have discovered the structure and shape of key receptors connecting neurons in the brain's cerebellum, which is located behind the brainstem and plays a critical role in functions such as coordinating movement, balance and cognition.

23 Jun 2025

New DNA test predicts chemotherapy resistance in cancer patients

Cancer Research UK-funded scientists at the University of Cambridge, in collaboration with the Spanish National Cancer Research Centre (CNIO) and Cambridge-based startup Tailor Bio, have created a test which can successfully predict whether cancer will resist common forms of chemotherapy treatment.

23 Jun 2025

Endometriosis linked to higher odds of autoimmune conditions

New research links endometriosis to autoimmune diseases, revealing shared mechanisms that may lead to earlier diagnosis and targeted treatments for patients.

23 Jun 2025