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First chemoimmunotherapy regimen approved by FDA for patients with diffuse large B-cell lymphoma

Today, the U.S. Food and Drug Administration granted accelerated approval to Polivy (polatuzumab vedotin-piiq), in combination with the chemotherapy bendamustine and a rituximab product (a combination known as "BR"), to treat adult patients with diffuse large B-cell lymphoma (DLBCL) that has progressed or returned after at least two prior therapies.

10 Jun 2019

Drug that targets the immune system can delay type 1 diabetes in high risk children, adults

A drug that targets the immune system can delay the onset of type 1 diabetes an average of two years in children and adults at high risk, according to findings from TrialNet's Teplizumab (anti-CD3) Prevention Study published in the New England Journal of Medicine.

10 Jun 2019

Discovery may lead to the development of early warning system for seizures

A new study has found a pattern of molecules that appear in the blood before a seizure happens. This discovery may lead to the development of an early warning system, which would enable people with epilepsy to know when they are at risk of having a seizure.

10 Jun 2019

Promising methods for early detection and treatment of rheumatoid arthritis

Rheumatoid arthritis is a chronic inflammatory autoimmune disorder that leads to significant health issues as well as high treatment costs. In this themed issue of Clinical Therapeutics, published by Elsevier, experts review multiple aspects of RA detection and intervention with the overall goal of moving the field closer to developing effective preventive measures.

10 Jun 2019

Trump administration cracks down on fetal tissue research

The Trump administration is cutting funding for fetal tissue research despite opposition from scientists and clinicians.

10 Jun 2019

Doctors urged to prescribe woodland walks for mental health problems

The Woodland Trust says the Japanese practice of “forest bathing” should be prescribed by doctors to tackle stress and other mental health problems.

10 Jun 2019

Undetected glucose disorders linked to myocardial infarction and periodontitis

People with undetected glucose disorders run a higher risk of both myocardial infarction and periodontitis, according to a study published in the journal Diabetes Care by researchers at Karolinska Institutet in Sweden.

10 Jun 2019

Mini-biographies help clinicians connect with patients

Bob Hall was recovering from yet another surgery in March 2014 when a volunteer walked into his hospital room. It had been a rocky recovery since his lung transplant three months earlier at the William S. Middleton Memorial Veterans Hospital in Madison, Wis.

10 Jun 2019

Study backs use of physician assistants, nurse practitioners for treating VA patients with diabetes

Veterans Affairs patients with diabetes have similar health outcomes regardless of whether their primary provider is a physician, nurse practitioner, or physician assistant, according to a Durham VA Health Care System study.

10 Jun 2019

CGM evaluations in long-term islet transplant recipients show near-normal glycemic profiles

Continuous glucose monitoring evaluations in islet transplant recipients who have been insulin independent for an average of 10 years show near-normal glycemic profiles and time-in-range metrics, according to data presented by the Diabetes Research Institute at the University of Miami Miller School of Medicine.

10 Jun 2019

Diabetes drug reduces cardiovascular events and kidney problems, study finds

A clinical trial that followed more than 9,900 people in 24 countries has found that the drug dulaglutide reduced cardiovascular events and kidney problems in middle-aged and older people with Type 2 diabetes.

10 Jun 2019

World’s first clinical guidance on anal sex after prostate cancer treatments

UK doctors and surgeons have formulated what is probably the world's first clinical guidance on anal sex before, during, and after diagnosis and treatment for prostate cancer.

10 Jun 2019

No lasting improvement in insulin secretion with diabetic medication

Adults with type 2 diabetes mellitus respond to medical treatment by producing more insulin, but there is no long-term effect on insulin secretion after treatment stops, concluded a pair of clinical trials.

9 Jun 2019

Prostate cancer diagnosis gets a boost from MRI

Traditionally prostate cancers have been diagnosed using biopsies of the tumour masses. New research from researchers at University College London (UCL) has shown that a more accurate diagnostic means for prostate cancers is MRI scans and targeted biopsies.

9 Jun 2019

AI tool can aid in the diagnosis of brain aneurysms

Doctors could soon get some help from an artificial intelligence tool when diagnosing brain aneurysms - bulges in blood vessels in the brain that can leak or burst open, potentially leading to stroke, brain damage or death.

8 Jun 2019

Posture impacts taste perception, finds study

Summertime is often filled with outdoor parties and food trucks, meaning you're spending more time standing up and eating. But if you want to actually enjoy your meal, researchers say you're better off finding a seat.

8 Jun 2019

Rapid fluid removal from patients with failing kidneys linked to increased risk of death

The faster fluid is removed using continuous dialysis from patients with failing kidneys, the higher the likelihood they will die in the next several months, according to a study published today in JAMA Network Open by University of Pittsburgh School of Medicine researchers.

8 Jun 2019

Vitamin D supplement does not prevent type 2 diabetes in adults at high risk, study finds

Taking a daily vitamin D supplement does not prevent type 2 diabetes in adults at high risk, according to results from a study funded by National Institute of Diabetes and Digestive and Kidney Diseases, part of the National Institutes of Health.

8 Jun 2019

Sleep-disordered breathing severity associated with epigenetic age acceleration

Increasing severity of sleep-disordered breathing and sleep disruption are associated with epigenetic age acceleration, according to preliminary results of a new study.

8 Jun 2019

NIH awards $23 million grant to study the diseases affecting people with HIV

The National Institutes of Health has awarded a seven-year, $23 million grant to researchers at Albert Einstein College of Medicine and Montefiore Health System to study HIV and the chronic illnesses that often accompany HIV infection, including cardiovascular and lung disease, diabetes, and cancer.

8 Jun 2019