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TKI introduction improves French CML patient survival

Real-world study findings from France show the significant impact tyrosine kinase inhibitor treatment has had on the survival of patients with Philadelphia chromosome-positive chronic myeloid leukaemia.

17 Feb 2015

Second-line bosutinib well tolerated by Japanese patients

Phase I/II clinical trial data support the use of bosutinib as second- or third-line tyrosine kinase inhibitor therapy in Japanese patients with Philadelphia chromosome-positive chronic myeloid leukaemia.

17 Feb 2015

Cabazitaxel therapy may be more effective in treating prostate cancer

Prostate cancer is the second leading cause of cancer for men in the United States. Only one class of chemotherapy called taxanes is effective against the disease.

17 Feb 2015

Fusobacterium necrophorum often causes severe sore throats in young adults

New research from the University of Alabama at Birmingham suggests that Fusobacterium necrophorum more often causes severe sore throats in young adults than streptococcus — the cause of the much better known strep throat.

17 Feb 2015

Researchers identify molecule that plays key role in aggressive thyroid cancer, other cancers

Cancer researchers at Mayo Clinic's campus in Jacksonville, Florida, have identified a molecule they say is important to survival of anaplastic thyroid carcinoma (ATC) — a lethal tumor with no effective therapies.

17 Feb 2015

CryoLife's revenues increase 5% to $37.2M in fourth quarter 2014

CryoLife, Inc., a leading medical device and tissue processing company focused on cardiac and vascular surgery, announced today its results for the fourth quarter and full year of 2014.

17 Feb 2015

Study: Most risk calculators used by clinicians overestimate risk of heart attack

Most "risk calculators" used by clinicians to gauge a patient's chances of suffering a heart attack and guide treatment decisions appear to significantly overestimate the likelihood of a heart attack, according to results of a study by investigators at Johns Hopkins and other institutions.

17 Feb 2015

Large majority of coronary patients fail to meet lifestyle, risk factor targets

The large majority of coronary patients in Europe are failing to achieve their lifestyle, risk factor and therapeutic targets as set out in the latest prevention guidelines.

17 Feb 2015

Wistar researchers identify new therapeutic target for aggressive form of ovarian cancer

Ovarian cancer is the deadliest of all cancers affecting the female reproductive system with very few effective treatments available. Prognosis is even worse among patients with certain subtypes of the disease. Now, researchers at The Wistar Institute have identified a new therapeutic target in a particularly aggressive form of ovarian cancer, paving the way for what could be the first effective targeted therapy of its kind for the disease.

16 Feb 2015

New study finds promising target for future therapies to treat breast and ovarian cancer patients

The Food and Drug Administration's recent approval of the drug olaparib for ovarian cancer patients with inherited mutations in the genes BRCA1 or BRCA2 came as welcome news to the thousands of women now eligible to receive it. A new study by Dana-Farber Cancer Institute scientists indicates that the pool of patients who can benefit from the drug is potentially much wider - and offers a ready means of identifying them.

16 Feb 2015

Harmless plant extract can help treat Cushing Disease

Cushing Disease, not to be confused with Cushing's Syndrome, is caused by a tumour in the pituitary gland in the brain. The tumour secrets increased amounts of the stress hormone adrenocorticotropin (ACTH) followed by cortisol release from the adrenal glands leading to rapid weight gain, elevated blood pressure and muscular weakness.

16 Feb 2015

Novartis’ heart failure medicine LCZ696 granted FDA priority review

LCZ696, a twice-a-day medicine being investigated for heart failure, acts to enhance the protective neurohormonal systems of the heart (NP system) while simultaneously suppressing the harmful effects of the overactive renin-angiotensin-aldosterone system (RAAS).

16 Feb 2015

20th annual edition of NCCN Guidelines for Breast Cancer published

Breast cancer is the most frequently diagnosed cancer globally and the leading cause of cancer-related death in women. However, the incidence of breast cancer has somewhat stabilized over the past few decades, and breast cancer mortality appears to be declining, suggesting a benefit from the combination of early detection and more effective treatment.

16 Feb 2015

Study suggests introduction of specific NGF to prevent neuronal degradation in Alzheimer's patients

Scientists at Karolinska Institutet have evaluated a new Alzheimer's therapy in which the patients receive an implant that stimulates the growth of a certain type of nerve cell. The results, which are published in the scientific journal Alzheimer's & Dementia, suggest that the introduction of a nerve growth factor can prevent neuronal degradation in Alzheimer's patients.

16 Feb 2015

New research shows that psychological factors affect treatment for back-related disability

People with back pain who have low expectations of acupuncture before they start a course of treatment will gain less benefit than those people who believe it will work, according to new research from the University of Southampton.

16 Feb 2015

Widely used clinical calculators overrate heart attack risk

16 Feb 2015

New study indicates that cancer patients rarely push for unnecessary tests, treatments

Physicians often blame patient demands for contributing to high medical costs, however, a new study involving more than 5,000 patient-clinician visits indicates that cancer patients rarely push for unnecessary tests and treatments from their health care providers.

16 Feb 2015

Therapy News and Research

TKI introduction improves French CML patient survival

Second-line bosutinib well tolerated by Japanese patients

Cabazitaxel therapy may be more effective in treating prostate cancer

Fusobacterium necrophorum often causes severe sore throats in young adults

Researchers identify molecule that plays key role in aggressive thyroid cancer, other cancers

CryoLife's revenues increase 5% to $37.2M in fourth quarter 2014

Study: Most risk calculators used by clinicians overestimate risk of heart attack

Large majority of coronary patients fail to meet lifestyle, risk factor targets

Wistar researchers identify new therapeutic target for aggressive form of ovarian cancer

New study finds promising target for future therapies to treat breast and ovarian cancer patients

Harmless plant extract can help treat Cushing Disease

Novartis’ heart failure medicine LCZ696 granted FDA priority review

20th annual edition of NCCN Guidelines for Breast Cancer published

Study suggests introduction of specific NGF to prevent neuronal degradation in Alzheimer's patients

New research shows that psychological factors affect treatment for back-related disability

Widely used clinical calculators overrate heart attack risk

New study indicates that cancer patients rarely push for unnecessary tests, treatments

Increasing opioid doses to manage chronic pain may intensify depression

MJC ICM works out general guidelines for intensive care medicine

Short-term cognitive behavioral therapy reduces suicide attempts among at-risk soldiers

Industry Focus eBook - Cell biology (5th edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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