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Northwestern Medicine researchers evaluate unique surgical method to treat chronic amputee pain

Northwestern Medicine® researchers are leading a new multi-center clinical trial to evaluate a unique surgical method, known as targeted muscle reinnervation (TMR), to treat chronic pain that can result from limb amputation. Around a quarter of all amputees develop chronic pain in the remaining portion of their amputated limb, which can include phantom limb syndrome (pain that is perceived in the portion of the limb that is gone), and prevents many patients from using prostheses.

5 Feb 2015

Battlefield blood transfusion protocol improves patient outcomes

Working to save the lives of military personnel suffering massive blood loss in the Afghanistan and Iraq wars, United States military trauma surgeons developed a blood transfusion protocol that is employed in most military and civilian hospitals today.

5 Feb 2015

Novel EPR oximetry technique may help clinicians directly measure oxygen in cancer, stroke patients

A novel Electron Paramagnetic Resonance (EPR) oximetry technique will help clinicians directly measure oxygen and schedule treatments at times of high oxygen levels in cancer and stroke patients to improve outcomes, The EPR team at Dartmouth's Geisel School of Medicine has found.

5 Feb 2015

Researchers develop smartphone accessory for rapid diagnosis of infectious diseases at point of care

A team of researchers, led by Samuel K. Sia, associate professor of biomedical engineering at Columbia Engineering, has developed a low-cost smartphone accessory that can perform a point-of-care test that simultaneously detects three infectious disease markers from a finger prick of blood in just 15 minutes.

5 Feb 2015

Johns Hopkins researchers successfully deliver new nanoparticle gene therapy to treat glioma in rats

Despite improvements in the past few decades with surgery, chemotherapy and radiation therapy, a predictably curative treatment for glioma does not yet exist. New insights into specific gene mutations that arise in this often deadly form of brain cancer have pointed to the potential of gene therapy, but it's very difficult to effectively deliver toxic or missing genes to cancer cells in the brain.

5 Feb 2015

Three Keck Medicine scientists of USC receive $4.3 million from CIRM for stem cell research

Three scientists from Keck Medicine of the University of Southern California have won grants exceeding $4.3 million from the California Institute for Regenerative Medicine for research that includes creating a temporary liver for transplant patients, finding novel ways to treat immune disorders and blood diseases and developing a new animal model for exploring diseases like heart failure, diabetes and neurodegenerative diseases.

5 Feb 2015

Nevro obtains new expanded MR-conditional labeling for Senza SCS system

Nevro Corp., a medical device company that has developed and commercialized an innovative, evidence-based neuromodulation platform for the treatment of chronic pain, today announced that it has received CE Mark for expanded MR-conditional labeling.

5 Feb 2015

Johns Hopkins student wins NCRC's 2015 Grand Prize

The National Collegiate Research Conference sponsored by the Harvard College Undergraduate Research Association awarded its 2015 Grand Prize to Mahima Sukumar, an undergraduate student at The Johns Hopkins University, working in the lab of Keri Martinowich, Ph.D., at the Lieber Institute for Brain Development.

5 Feb 2015

Diplomat to dispense FDA-approved IBRANCE (palbociclib) to treat metastatic breast cancer

Diplomat Pharmacy, Inc., the nation's largest independent specialty pharmacy, announced today it will dispense Pfizer's new breakthrough medication, IBRANCE (palbociclib), starting tomorrow, Feb. 5.

4 Feb 2015

Brain scans can predict therapeutic responses to talk therapy

UNC School of Medicine researchers have shown that brain scans can predict which patients with clinical depression are most likely to benefit from a specific kind of talk therapy.

4 Feb 2015

Genomics of papillary thyroid carcinoma (PTC): an interview with Professor Thomas J. Giordano

There are two types of thyroid cells and therefore there are two broad types of thyroid cancer. Medullary carcinoma is derived from parafollicular or C cells, whereas follicular cells give rise to several types of thyroid cancers.

4 Feb 2015

FDA accepts Sangamo BioSciences' IND for SB-BCLmR-HSPC genome editing approach

Sangamo BioSciences, Inc. announced today that an Investigational New Drug (IND) application for the company's SB-BCLmR-HSPC genome editing approach, which is designed to provide a one-time lasting therapy for beta-thalassemia, has been accepted by the U.S. Food and Drug Administration and is now active.

4 Feb 2015

Parents can pass silenced genes to offspring through a specific mechanism

For more than a century, scientists have understood the basics of inheritance: if good genes help parents survive and reproduce, the parents pass those genes along to their offspring. And yet, recent research has shown that reality is much more complex: genes can be switched off, or silenced, in response to the environment or other factors, and sometimes these changes can be passed from one generation to the next.

4 Feb 2015

Ultrasound narrows which breast cancer patients need underarm lymph nodes removed

Which breast cancer patients need to have underarm lymph nodes removed? Mayo Clinic-led research is narrowing it down. A new study finds that not all women with lymph node-positive breast cancer treated with chemotherapy before surgery need to have all of their underarm nodes taken out.

4 Feb 2015

Edwards Lifesciences’ net sales increase 15% to $618.0M in Q4 2014

Edwards Lifesciences Corporation, the global leader in the science of heart valves and hemodynamic monitoring, today reported net income for the quarter ended December 31, 2014 of $109.2 million, or $1.00 per diluted share, and non-GAAP1 net income of $116.5 million, or $1.06 per diluted share. Net income for the same period a year earlier was $75.1 million, or $0.68 per diluted share, and non-GAAP net income was $105.0 million, or $0.95 per diluted share.

4 Feb 2015

TMM journal reviews latest advances in reproductive medicine

The journal Trends in Molecular Medicine reviews the latest advances in reproductive medicine--from mitochondrial replacement therapy to the infant microbiome--with a special issue on "Nurturing the Next Generation," published February 3, 2015.

4 Feb 2015

Study demonstrates therapeutic potential of new class of synthetic oligonucleotides for DMD treatment

Research efforts associating scientists from the CNRS, UVSQ and INSERM within the Laboratoire END-ICAP, working in collaboration with a team from the University of Bern, has demonstrated the therapeutic potential of a new class of synthetic oligonucleotides in the treatment of Duchenne muscular dystrophy (DMD) using RNA "surgery".

4 Feb 2015

Research: New molecule safeguards heart from toxic breast cancer drugs, kills cancerous tumour

A new molecule has been found that protects the heart from toxic breast cancer drugs and also kills the cancerous tumour. The research from Italy addresses the burgeoning problem of heart disease in cancer survivors and is announced by the European Society of Cardiology today on World Cancer Day.

4 Feb 2015

Researchers develop optimised PSA screening programme for prostate cancer

As an indicator of prostate cancer, the PSA test is regarded in urology as highly controversial since it is not always unequivocal. A team of researchers from the Comprehensive Cancer Center at the MedUni Vienna and Vienna General Hospital has now developed a programme that compensates the shortfalls of PSA screening with methods from personalised medicine. As a result, prostate cancer screening is able to reach a new level of quality.

4 Feb 2015

Study could lead to potential therapeutic targets to treat Ewing Sarcoma

A University of Colorado Cancer Center study published in the journal PLoS One finds alterations in expression of genes PIK3R3 and PTEN, more commonly observed in adult tumors, in the rare, young-adult bone cancer Ewing Sarcoma, potentially offering ways to improve therapy.

4 Feb 2015

Therapy News and Research

Northwestern Medicine researchers evaluate unique surgical method to treat chronic amputee pain

Battlefield blood transfusion protocol improves patient outcomes

Novel EPR oximetry technique may help clinicians directly measure oxygen in cancer, stroke patients

Researchers develop smartphone accessory for rapid diagnosis of infectious diseases at point of care

Johns Hopkins researchers successfully deliver new nanoparticle gene therapy to treat glioma in rats

Three Keck Medicine scientists of USC receive $4.3 million from CIRM for stem cell research

Nevro obtains new expanded MR-conditional labeling for Senza SCS system

Johns Hopkins student wins NCRC's 2015 Grand Prize

Diplomat to dispense FDA-approved IBRANCE (palbociclib) to treat metastatic breast cancer

Brain scans can predict therapeutic responses to talk therapy

Genomics of papillary thyroid carcinoma (PTC): an interview with Professor Thomas J. Giordano

FDA accepts Sangamo BioSciences' IND for SB-BCLmR-HSPC genome editing approach

Parents can pass silenced genes to offspring through a specific mechanism

Ultrasound narrows which breast cancer patients need underarm lymph nodes removed

Edwards Lifesciences’ net sales increase 15% to $618.0M in Q4 2014

TMM journal reviews latest advances in reproductive medicine

Study demonstrates therapeutic potential of new class of synthetic oligonucleotides for DMD treatment

Research: New molecule safeguards heart from toxic breast cancer drugs, kills cancerous tumour

Researchers develop optimised PSA screening programme for prostate cancer

Study could lead to potential therapeutic targets to treat Ewing Sarcoma

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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