Biomarker News and Research

RSS

A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

NeuroVision Imaging receives ADDF funding to develop biomarker tests for Alzheimer's disease

NeuroVision Imaging Inc., announced today it has received an investment from the Alzheimer's Drug Discovery Foundation to support developing reliable, affordable biomarker tests for Alzheimer's disease and other forms of dementia and neurodegenerative disorders.

3 Feb 2021

Study finds high bleeding risk in a sub-group of COVID-19 patients

The human body strives to keep itself in homeostasis, or balance. When blood clots are created, the body's innate response is to break the clots down to prevent significant health problems from arising.

1 Feb 2021

Phase III study of (m)RNA expression did not confer significant advantage for stage II-III lung cancer

A phase III study examining whether messenger (m)RNA expression correlated with sensitivity or resistance to chemotherapy did not confer a statistically significant advantage in overall survival for patients with resected stage II-III non-small cell lung cancer (NSCLC), according to research presented at the International Association for the Study of Lung Cancer World Conference on Lung Cancer.

31 Jan 2021

DSMB recommends continuation of Phase 2/3 study of opaganib for severe COVID-19

RedHill Biopharma Ltd., a specialty biopharmaceutical company, today announced that the independent Data Safety Monitoring Board (DSMB) for the global Phase 2/3 study of opaganib in patients with severe COVID-19, unanimously recommended to continue the study following a pre-scheduled futility review of unblinded efficacy data from the first 135 patients treated in the study and safety data from the first 175 patients.

30 Jan 2021

Scientists create new way to detect COVID-19 proteins and antibodies

Scientists have created a new way to detect the proteins that make up the pandemic coronavirus, as well as antibodies against it. They designed protein-based biosensors that glow when mixed with components of the virus or specific COVID-19 antibodies.

29 Jan 2021

Melatonin synthesized in the lungs acts as a barrier against SARS-CoV-2

Melatonin synthesized in the lungs acts as a barrier against SARS-CoV-2, preventing expression of genes that encode proteins in cells such as resident macrophages in the nose and pulmonary alveoli, and epithelial cells lining the alveoli, all of which are entry points for the virus.

28 Jan 2021

Gyros Protein Technologies introduces Gyrolab Bioaffy 4000 CD to extend sensitivity of immunoassay CD range

Gyros Protein Technologies AB today announced the introduction of Gyrolab® Bioaffy™ 4000 CD for immunoassay applications in biotherapeutic workflows.

From Gyros Protein Technologies AB 27 Jan 2021

Initial stages of breast cancer could be detected more accurately with new proteomics-based technology

Breast cancer, even at its initial stages, could be detected earlier and more accurately than current techniques using blood samples and a unique proteomics-based technology, according to findings of a study led by the Translational Genomics Research Institute (TGen), an affiliate of City of Hope.

26 Jan 2021

Pain-free microneedle patch can capture biomarkers from interstitial fluid

Blood draws are no fun. They hurt. Veins can burst, or even roll - like they're trying to avoid the needle too, Oftentimes, doctors use blood samples to check for biomarkers of disease: antibodies that signal a viral or bacterial infection, such as SARS-CoV-2, the virus responsible for COVID-19, or cytokines indicative of inflammation seen in conditions such as rheumatoid arthritis and sepsis.

26 Jan 2021

New discovery could lead to faster and more effective treatments for chronic health complications

A world-first discovery by researchers at Monash University and The University of Queensland could lead to faster and more effective treatments for chronic health complications, such as cardiovascular disease and cancer, with 'fluorescent' in vivo biosensors.

26 Jan 2021

Researchers develop method for presymptomatic COVID-19 detection

An encouraging new study by researchers at University College London, UK, reports the potential of a form of COVID-19 testing which can detect presymptomatic cases.

26 Jan 2021

Reduced expression of TBX15 in tumor tissue represents a prognostic biomarker for HCC patients

The cover for issue 52 of Oncotarget features Figure 1, "Volcano plots of DNA methylation in tumor tissues compared with nontumor tissue," published in "Reduction of T-Box 15 gene expression in tumor tissue is a prognostic biomarker for patients with hepatocellular carcinoma" by Morine, et al. which reported that the authors conducted a genome-wide analysis of DNA methylation of the tumor and non-tumor tissue of 15 patients with Hepatocellular carcinoma (HCC), and revealed TBX15 was the most hypermethylated gene of the tumor.

25 Jan 2021

Dynamic, customized treatment approaches for gastroesophageal cancers may improve survival rates

A phase 2 clinical trial providing personalized treatments based on the genetic profile of metastatic tumors in gastroesophageal cancers has found that using customized treatment approaches, and adapting them over time as tumors become resistant, led to higher rates of survival compared to historical controls.

21 Jan 2021

Abnormal hyperactivation in the brain could be an early biomarker of Alzheimer's disease

Abnormally hyperactive areas in the brain may help better predict the onset of Alzheimer's disease, according to findings of a research team led by Université de Montreal psychology professor Sylvie Belleville, scientific Director of the Institut universitaire de gériatrie de Montréal research centre.

21 Jan 2021

Study finds racial disparities in side-specific biological aging of the colon

The colons of African-Americans and people of European descent age differently, new research reveals, helping explain racial disparities in colorectal cancer - the cancer that killed beloved "Black Panther" star Chadwick Boseman at only 43.

21 Jan 2021

Vegan diet has a broad effect on children's metabolism, study reveals

University of Helsinki researchers report a comprehensive pilot study on the metabolic effects of full vegan diet on young children.

21 Jan 2021

Automated method tracks cortical origin and initial spread of TAU proteins in Alzheimer’s disease

Researchers have developed an automated method that can track the development of harmful clumps of TAU protein related to Alzheimer's disease in the brain, according to work involving 443 individuals.

20 Jan 2021

Insulin resistance, diabetes and metabolic syndrome contribute to premature coronary events in women

While deaths related to heart disease have declined among older people, studies suggest that death rates among younger patients have remained stagnant or increased slightly.

20 Jan 2021

Researchers receive $460,000 NIH grant for brain imaging study

Michael Alosco, PhD, associate professor of neurology at Boston University School of Medicine, and Gil Rabinovici, MD, professor of neurology and radiology at the University of California San Francisco have been awarded a two-year, $460,000 grant from the National Institute of Neurological Disorders and Stroke, which is part of the National Institutes of Health.

19 Jan 2021

Owlstone Medical introduces breath biopsy panel for respiratory diseases

Owlstone Medical, the leader in Breath Biopsy® for applications in disease detection, today introduced the Respiratory Diseases Research Use Only Panel.

From Owlstone Medical Ltd 19 Jan 2021

Biomarker News and Research

Further Reading

NeuroVision Imaging receives ADDF funding to develop biomarker tests for Alzheimer's disease

Study finds high bleeding risk in a sub-group of COVID-19 patients

Phase III study of (m)RNA expression did not confer significant advantage for stage II-III lung cancer

DSMB recommends continuation of Phase 2/3 study of opaganib for severe COVID-19

Scientists create new way to detect COVID-19 proteins and antibodies

Melatonin synthesized in the lungs acts as a barrier against SARS-CoV-2

Gyros Protein Technologies introduces Gyrolab Bioaffy 4000 CD to extend sensitivity of immunoassay CD range

Initial stages of breast cancer could be detected more accurately with new proteomics-based technology

Pain-free microneedle patch can capture biomarkers from interstitial fluid

New discovery could lead to faster and more effective treatments for chronic health complications

Researchers develop method for presymptomatic COVID-19 detection

Reduced expression of TBX15 in tumor tissue represents a prognostic biomarker for HCC patients

Dynamic, customized treatment approaches for gastroesophageal cancers may improve survival rates

Abnormal hyperactivation in the brain could be an early biomarker of Alzheimer's disease

Study finds racial disparities in side-specific biological aging of the colon

Vegan diet has a broad effect on children's metabolism, study reveals

Automated method tracks cortical origin and initial spread of TAU proteins in Alzheimer’s disease

Insulin resistance, diabetes and metabolic syndrome contribute to premature coronary events in women

Researchers receive $460,000 NIH grant for brain imaging study

Owlstone Medical introduces breath biopsy panel for respiratory diseases

Event guide: 15th World Clinical Biomarkers & CDx Europe eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo