Inflammation News and Research

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Researchers develop mouse model to study neutrophilic asthma

A better understanding of inflammation and lung immunity over the past two decades has led to new, innovative treatments for asthma, including biologic therapies.

18 Feb 2025

New review sheds light on links between Alzheimer's and metabolic syndrome

Alzheimer's disease (AD), the most common form of dementia, continues to remain one of modern medicine's greatest challenges.

18 Feb 2025

Senolytic agent ABT-263 mitigates GI cancer risk after radiation exposure

A new research paper was published by Aging (Aging-US) on January 8, 2025, in Volume 17, Issue 1, titled "Senolytic agent ABT-263 mitigates low- and high-LET radiation-induced gastrointestinal cancer development in Apc1638N/+ mice."

18 Feb 2025

Fungal component may protect against flu-related lung damage

A component found in all fungi may provide a shield against flu-related lung damage, according to a new study.

18 Feb 2025

Researchers identify MLC1 as potential target in multiple sclerosis

Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system caused by the immune system. B cells, which are a type of white blood cell, play a role in the development of MS and are thus a target for therapies.

18 Feb 2025

Strengthening the gut barrier may halt Crohn’s disease progression

Researchers at the University of Gothenburg, Sweden, have uncovered a critical mechanism that may pave the way for innovative treatments for Crohn's disease.

18 Feb 2025

Air pollution in late pregnancy linked to higher NICU admissions for newborns

Exposure to traffic pollutants before birth is linked to increased NICU admissions, stressing the importance of addressing air quality for neonatal health.

18 Feb 2025

Scientists pinpoint metabolic failure as the cause of muscle loss in aging

A multi-omics study reveals that impaired branched-chain amino acid (BCAA) catabolism is a key driver of sarcopenia, suggesting it as a potential therapeutic target.

17 Feb 2025

Do probiotics enhance sports performance?

Researchers found that probiotics may enhance endurance, recovery, and immune function in athletes, but the evidence for strength and power performance remains limited.

17 Feb 2025

Sweat fails to match blood in tracking inflammation after heart attacks

Researchers found that while sweat biomarkers remain stable, plasma biomarkers show significant inflammatory changes after a heart attack, highlighting the limitations of sweat analysis for tracking recovery.

17 Feb 2025

AI predicts preterm birth risk with 82% accuracy

Researchers used machine learning models to predict preterm birth risk, identifying linear SVMs as the most accurate, with key predictors including inflammation and blood composition markers.

17 Feb 2025

Study shows how pituitary macrophages impact hormone regulation

Finnish researchers show in a new study that pituitary macrophages, the immune cells located in the pituitary gland, help regulate hormonal balance. It is possible that in the future, macrophage cells could be used to treat endocrine disorders that can lead, for example, to infertility.

17 Feb 2025

Stanford researchers identify key variants linked to inherited cancer risk

Thousands of single changes in the nucleotides that make up the human genome have been associated with an increased risk of developing cancer.

17 Feb 2025

Diabetes drugs may boost brain health but experts warn of risks

Researchers reviewed 374 studies to explore how GLP-1RAs, originally for diabetes, may impact brain health, finding potential benefits for dementia and addiction but inconsistent results for mood disorders.

16 Feb 2025

Vaping and gum health: How does it compare to smoking?

A systematic review found that e-cigarette users show increased plaque and inflammation markers compared to non-smokers, though their gum health fares better than traditional smokers. However, the certainty of these findings is low due to study bias.

16 Feb 2025

New research sheds light on brain inflammation in Alzheimer's

Brain inflammation, while a crucial part of the body's immune response, takes on a detrimental role in Alzheimer's disease.

16 Feb 2025

New gut-on-chip model could revolutionize immunotherapy for melanoma

A team of researchers from the European Institute of Oncology and the Politecnico di Milano, coordinated by Luigi Nezi, Team Leader of the Department of Experimental Oncology, European Institute of Oncology, and Marco Rasponi, Full Professor of the Department of Electronics, Informatics and Bioengineering, Politecnico di Milano, have developed a "gut-on-chip" (a miniature model of the human intestine on a chip-sized device) capable of reproducing the main features of intestinal inflammation and of predicting the response of melanoma patients to immunotherapy treatment.

14 Feb 2025

Extracellular vesicles show promise for diagnosing and treating oral diseases

A comprehensive review has explored the diverse roles of extracellular vesicles (EVs) in the oral and maxillofacial region, highlighting their immense potential in disease detection, targeted therapies, and tissue regeneration.

14 Feb 2025

Infants with cystic fibrosis show stunted gut microbiome development

Findings from a new Dartmouth-led study, published in the journal mBio, highlight key differences in the gut microbiome (communities of bacteria) of infants with cystic fibrosis (CF) compared to that of healthy infants, and how these alterations may adversely affect their health.

14 Feb 2025

Addressing the global challenge of bacterial STIs

According to the World Health Organization (WHO), hundreds of millions of new cases of bacterial sexually transmitted infections (STIs) are reported worldwide each year. Many infections go undiagnosed due to their often silent symptoms, contributing to transmission, disease and complications such as infertility and miscarriage.

14 Feb 2025