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Researchers identify inhibitors of the SARS-CoV-2 Nsp14 N7-methyltransferase

A recent study identified inhibitors for SARS-CoV-2 non-structural protein 14 (Nsp14).

17 Jan 2023

New test 'fishes' for multiple respiratory viruses using DNA as 'bait'

A new test that 'fishes' for multiple respiratory viruses at once using single strands of DNA as 'bait', and gives highly accurate results in under an hour, has been developed by Cambridge researchers.

16 Jan 2023

Researchers find a simple way to predict the properties of compounds of drugs with metals

RUDN University chemists, biologists and physicians have found a simple way to predict the properties of compounds of drugs with metals.

16 Jan 2023

Study identifies new tau regulators as viable therapeutic targets for Alzheimer's and other tauopathies

Neurodegenerative diseases affect millions of people worldwide and as our life expectancy increases, more individuals are expected to be affected in the coming decades.

16 Jan 2023

The loss of epigenetic information accelerates the aging process

A new study in the journal Cell aimed to determine whether epigenetic changes are a cause of mammalian aging.

15 Jan 2023

Chemists find a simple way to produce previously inaccessible chiral Z-alkenes

Chemists from the University of Groningen have found a simple way to produce previously inaccessible chiral Z-alkenes, molecules that offer a significant synthetic short-cut for the production of bioactive molecules.

13 Jan 2023

Altering a cellular process can lead stem cells to die or regenerate, study finds

A new study led by Cedars-Sinai and the University of California, San Francisco (UCSF), has determined that altering a cellular process can lead stem cells - cells from which other cells in the body develop - to die or regenerate.

13 Jan 2023

SARS-CoV-2 WA1/2020, Delta and Omicron strains found to infect human sensory neurons

Researchers evaluated the impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on the peripheral nervous system (PNS).

13 Jan 2023

LJI scientists uncover how OGT enzyme keeps cells healthy

Researchers at La Jolla Institute for Immunology have at last uncovered how an enzyme called O-GlcNAc transferase (OGT) keeps cells healthy.

12 Jan 2023

Study reveals why older male fruit flies are more likely to pass mutations onto their offspring

The male reproductive system serves as a hotspot for the emergence of new genes. Perhaps that explains why more new mutations are inherited from fathers than from mothers.

12 Jan 2023

The effect of amino acid substitutions in variants of concern on RBD:ACE2 bond kinetics

Researchers explored the effects of mutations in the SARS-CoV-2 variants of concern on viral transmission.

12 Jan 2023

Pheno Therapeutics announces worldwide license from UCB to a novel program for neurodegenerative disease

Pheno Therapeutics Limited., a biotechnology company focused on the discovery and development of small molecule therapeutics that promote remyelination for the treatment of neurological diseases such as multiple sclerosis, announced today it has entered into an exclusive worldwide license agreement with UCB.

12 Jan 2023

Study analyzes the viability of new nanomolecule as drug delivery vehicle

A new study by the University of Barcelona has analyzed the viability of a new nanomolecule as drug delivery vehicle.

11 Jan 2023

Simple method increases the efficacy of T cell therapy by cytokine conjugation

The recent years have seen a wave of adoptive cell therapies (ACTs), a type of immunotherapy in which T cells (T cell transfer therapy) and other immune cells are obtained from patients, activated and multiplied outside the body, and infused in larger numbers back into the blood circulation to help fight cancers.

11 Jan 2023

Generative AI approach unlocks path to accelerated antibody drug creation for novel therapeutic targets

A recent study used generative AI models to develop de novo design antibodies against three distinct targets in a zero-shot fashion.

11 Jan 2023

Nanopore-based sensing device can provide volume information about tau and tubulin proteins

Tau and tubulin proteins are one of the leading causes of many neurodegenerative diseases, such as Alzheimer's and Parkinson's.

10 Jan 2023

Developing new tools to accelerate spatial genomics and drug discovery

We speak to Dr. George Emanuel from Vizgen about their new MERSCOPE Platform and how it is accelerating the field of drug discovery by combining both single-cell and spatial genomics.

From Vizgen 10 Jan 2023

Imaris launches 10.0, an AI-powered software for fast and accurate detection of neurons, microglia and blood vessels

Oxford Instruments - Andor has today released Imaris 10.0, the latest version of its market-leading microscopy image analysis software.

From Andor Technology Ltd. 10 Jan 2023

Daily intake of almonds changes the metabolism to recover faster after exercise

A new randomized controlled trial showed that participants who daily ate 57g almonds over four weeks had a 69% higher level of the beneficial oxylipin molecule 12,13-dihydroxy-9Z-octadecenoic acid in their blood after a 90 minute session of eccentric exercise than control volunteers.

10 Jan 2023

Study uncovers molecular features responsible for the development, progression of metastatic breast cancer

A multi-institutional national study has identified unique molecular features responsible for the development and progression of metastatic breast cancer.

9 Jan 2023

Molecule News and Research

Researchers identify inhibitors of the SARS-CoV-2 Nsp14 N7-methyltransferase

New test 'fishes' for multiple respiratory viruses using DNA as 'bait'

Researchers find a simple way to predict the properties of compounds of drugs with metals

Study identifies new tau regulators as viable therapeutic targets for Alzheimer's and other tauopathies

The loss of epigenetic information accelerates the aging process

Chemists find a simple way to produce previously inaccessible chiral Z-alkenes

Altering a cellular process can lead stem cells to die or regenerate, study finds

SARS-CoV-2 WA1/2020, Delta and Omicron strains found to infect human sensory neurons

LJI scientists uncover how OGT enzyme keeps cells healthy

Study reveals why older male fruit flies are more likely to pass mutations onto their offspring

The effect of amino acid substitutions in variants of concern on RBD:ACE2 bond kinetics

Pheno Therapeutics announces worldwide license from UCB to a novel program for neurodegenerative disease

Study analyzes the viability of new nanomolecule as drug delivery vehicle

Simple method increases the efficacy of T cell therapy by cytokine conjugation

Generative AI approach unlocks path to accelerated antibody drug creation for novel therapeutic targets

Nanopore-based sensing device can provide volume information about tau and tubulin proteins

Developing new tools to accelerate spatial genomics and drug discovery

Imaris launches 10.0, an AI-powered software for fast and accurate detection of neurons, microglia and blood vessels

Daily intake of almonds changes the metabolism to recover faster after exercise

Study uncovers molecular features responsible for the development, progression of metastatic breast cancer

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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