Immune System News and Research

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Promising new molecular targets and treatment approaches for some of the most malignant brain tumors

The first study identified a protein that seems to control the malignant features of brain tumor cells, suggesting a new treatment target for anti-cancer drugs. Researchers found that a little-known protein called Fra-1 was effective in controlling vascular endothelial growth factor D, a factor that promotes the growth of new blood vessels in most malignant brain tumors.

8 May 2005

Neutrophils dictate whether our immune system will permit or prevent bacterial infections

New research on a bacterium that can survive encounters with specific immune system cells has strengthened scientists' belief that these plentiful white blood cells, known as neutrophils, dictate whether our immune system will permit or prevent bacterial infections.

5 May 2005

War on AIDS needs food

The five billion dollars earmarked by U.S. President George W. Bush to fight HIV/AIDS could be wasted if his administration does not increase food aid resources, asserted the head of a leading development organization.

4 May 2005

Vaccine developed at Rockefeller University boosts natural killer T cells in patients with cancer

A new vaccine designed at The Rockefeller University boosted a type of fast-responding immune system cell called the natural killer T (NKT) cell in patients with advanced cancer. The study surprised researchers by revealing the ability of these NKT cells to spur other, slower-responding immune cells to go to work.

4 May 2005

Two-photon imaging gives real-time video of cells in living tissue

Biologists have a new tool to track and videotape cells moving about inside living tissue.

3 May 2005

Scientists use tobacco plants to create antibodies against tumor cells

Scientists at Jefferson Medical College are using tobacco plants to produce monoclonal antibodies – tiny guided protein missiles – that can target and hunt down cancer cells. The plants promise to provide a cheaper, faster method of producing anticancer antibodies, raising hopes that the technology can one day be used in humans.

3 May 2005

Whooping cough makes a comeback

The latest comeback in the health arena is whooping cough and experts are sufficiently concerned for the US government to approve the first whooping cough booster shot meant just for adolescents. The shot will be added to a booster shot against two other diseases, tetanus and diphtheria, that children already get sometime between ages 10 and 18.

3 May 2005

Critical lock and key mechanism found for the assembly of tumor blood vessels

A critical lock and key mechanism that allows the final step in the completion of new blood vessel formation has been identified by a University of California, San Diego (UCSD) School of Medicine team in research that promises to lead to a new way to halt tumor growth by cutting off the tumor blood supply.

3 May 2005

College freshies show weaker immune responses

Being a college freshie may have more ramifications than being lonely and missing Mum's cooking, according to a new study at Carnegie Mellon University in Pittsburgh which shows that first-year students had a weaker immune response to the flu shot than did other students, and confirms suspicions that going to college challenges both mind and body.

2 May 2005

Researchers benchmark the prevalence of vitamin A deficiency, anemia, iodine-deficiency disorders and underweight children as measures of malnutrition in developing regions

International health advocates and policymakers still have work to do to meet the nutrition goals set by the United Nations General Assembly Special Session on Children in 2002, according to a survey of nutrition needs in developing regions published by Tulane University researchers.

2 May 2005

Loneliness and social network appear to make independent contributions to immunity

A new study at Carnegie Mellon University in Pittsburgh confirms how college challenges both mind and body, by demonstrating that lonely first-year students mounted a weaker immune response to the flu shot than did other students. The study appears in the May issue of Health Psychology, which is published by the American Psychological Association (APA).

2 May 2005

Age-related macular degeneration is triggered, possibly by an infection

Age-related macular degeneration, the leading cause of blindness in the elderly, occurs when a common inherited gene variation is triggered, possibly by an infection, according to a new study led by researchers at Columbia University Medical Center and the University of Iowa, with an international research team.

1 May 2005

Antibiotic minocycline might help alleviate HIV's negative effects on the brain and central nervous system

By studying animals, Johns Hopkins researchers have discovered that the antibiotic minocycline might help alleviate HIV's negative effects on the brain and central nervous system, problems that can develop even though antiretroviral therapy controls the virus elsewhere in the body.

1 May 2005

Researchers show protein's role in stopping bacterial-induced inflammation

In findings that could have implications for autoimmune disorders and drug-resistant bacterial infections, researchers at the University of California, San Diego (UCSD) School of Medicine have identified a key protein involved in the appropriate shut-down of inflammation following an immune response to invading pathogens.

28 Apr 2005

Generex begins testing new vaccine for breast cancer patients

Generex Biotechnology Corporation announced today that the first patients had received a novel therapeutic vaccine developed by its wholly owned subsidiary, Antigen Express as part of the Company's Phase I Trial. The Trial will include between 16 and 24 patients.

28 Apr 2005

Cancer treatment - timing is everything

Research led by a cancer biologist at The Cleveland Clinic Lerner Research Institute has identified a molecular mechanism that links the body's internal clock to daily variations in how a patient responds to cancer treatment.

28 Apr 2005

Respiratory syncytial virus affects the elderly and high-risk adults as much as influenza

Respiratory syncytial virus (RSV), primarily seen as a cause of illness in infants and children, often affects the elderly and high-risk adults as much as influenza, a study by University of Rochester Medical Center researchers demonstrates.

27 Apr 2005

Molecular switch may help fight off MRSA

The discovery of a 'molecular switch' could lead to new ways of treating infections such as MRSA, and inflammatory diseases like arthritis.

27 Apr 2005

Scientists add an important piece to the intricate puzzle of type-1 diabetes

For some time, scientists have known that a regenerative or repair process -- involving the development of specialized structures called tubular complexes -- is switched on during physical and chemical trauma to the pancreas (the gland that manufactures and secretes crucial insulin in the body).

27 Apr 2005

National clinical trial examines new option for kidney cancer patients

The trial, which opened last September, offers research subjects who qualify a new, targeted therapy in addition to standard immune therapy. The drug combination is being studied in a national Phase II clinical trial led by OHSU Cancer Institute researcher Christopher Ryan, M.D., through the Southwest Oncology Group, one of the largest clinical trial cooperative groups in the United States.

27 Apr 2005

Immune System News and Research

Promising new molecular targets and treatment approaches for some of the most malignant brain tumors

Neutrophils dictate whether our immune system will permit or prevent bacterial infections

War on AIDS needs food

Vaccine developed at Rockefeller University boosts natural killer T cells in patients with cancer

Two-photon imaging gives real-time video of cells in living tissue

Scientists use tobacco plants to create antibodies against tumor cells

Whooping cough makes a comeback

Critical lock and key mechanism found for the assembly of tumor blood vessels

College freshies show weaker immune responses

Researchers benchmark the prevalence of vitamin A deficiency, anemia, iodine-deficiency disorders and underweight children as measures of malnutrition in developing regions

Loneliness and social network appear to make independent contributions to immunity

Age-related macular degeneration is triggered, possibly by an infection

Antibiotic minocycline might help alleviate HIV's negative effects on the brain and central nervous system

Researchers show protein's role in stopping bacterial-induced inflammation

Generex begins testing new vaccine for breast cancer patients

Cancer treatment - timing is everything

Respiratory syncytial virus affects the elderly and high-risk adults as much as influenza

Molecular switch may help fight off MRSA

Scientists add an important piece to the intricate puzzle of type-1 diabetes

National clinical trial examines new option for kidney cancer patients

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