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Developing stem cell sheet for enhancement of angiogenesis which promotes cardiac repair

Myocardial infarction is an ischemic disease in which a coronary artery supplying blood to the heart muscle is stenotic or obstructed, resulting in cardiac tissue necrosis.

16 Dec 2022

Study shows how a specific gut microbe-generated byproduct is linked to heart failure risk

New research at Cleveland Clinic expands the link between what we eat and how the gut microbiome impacts our susceptibility to develop different diseases – in this case, how a specific gut microbe-generated byproduct is linked to heart failure risk.

16 Dec 2022

Common type 2 diabetes drug requires the presence of GDF15 cytokine to present antidiabetic effects

Metformin, the most prescribed drug for treating diabetes mellitus, known as type 2 diabetes, requires the presence of the growth differentiation factor 15 (GDF15) —a protein whose expression increases in response to cellular stress— to present its antidiabetic effects.

16 Dec 2022

Trial results confirm the safety of three different Ebola vaccine regimens

Ebola epidemics occur periodically in various sub-Saharan African countries. While vaccines exist and have already received WHO Prequalification against the Zaire ebolavirus species, it is essential to pursue and intensify efforts to supplement the available data to develop a safe and effective Ebola vaccine strategies in adults and children alike.

16 Dec 2022

High-speed 5G network effective in providing telerehabilitation and teletreatment in remote community

Japan's population is rapidly aging. As a result, new challenges have emerged as an increased number of elderly people, many of whom live in isolated parts of the country, need medical and nursing care despite inadequate medical resources.

16 Dec 2022

Ceramide blockers prevent the loss of muscle mass during aging in mice

During aging, mice, like humans, become inactive and lose muscle mass and strength. A team of scientists led by Johan Auwerx at EPFL have now discovered that when mice age, their muscles become packed with ceramides.

16 Dec 2022

Changing heart cell programming can reverse the lasting damage caused by heart attacks

Back in 1971, the Bee Gees asked, "How can you mend a broken heart?". Now, researchers from Japan reveal that they may just have found a way to repair cardiac damage in patients suffering from chronic heart attack and heart failure.

16 Dec 2022

Researchers discover previously unknown mechanism for how 'starvation response' is triggered

Body cells burn off fat reserves when nutrient supply from food ceases. A team led by Professor Volker Haucke and Dr. Wonyul Jang from the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) has now discovered a previously unknown mechanism for how this “starvation response” is triggered, and what can inhibit it.

15 Dec 2022

Consumption of artificially sweetened beverages not linked to woman's risk of urinary incontinence

Urinary incontinence affects nearly 20% of women aged older than 50 years. Many factors can influence a woman's risk of urinary incontinence.

15 Dec 2022

Edible plant-based ink could reduce the cost of cultured meat production

Cultured meat (also known as cell-based or lab-grown meat) is a promising, more environmentally friendly alternative to meat produced from traditional livestock farming.

15 Dec 2022

Tiny messenger can be promising candidate for treatment of diseases associated with muscular atrophy

WNT messenger proteins are crucial for a variety of cellular functions. A specific WNT messenger can increase muscle mass and improve regeneration in skeletal muscle.

14 Dec 2022

Vitamin D supplements reduce the risk of dynapenia in older people by 78%

Vitamin D plays an important role in the regulation of calcium and phosphorus absorption by the organism.

13 Dec 2022

Researchers identify molecular determinants of post-infection long-COVID

In a recent study published in the journal Nature Medicine, researchers presented a transcriptome-wide assessment of blood gene expression changes that occur in acute COVID-19 (coronavirus disease 2019) and are associated with PASC (post-acute sequelae of COVID-19), commonly known as long-COVID.

13 Dec 2022

How human cell atlases provide the missing links between genes, diseases and therapies

A Nature Medicine journal perspective article describes the potential of cell atlases in shaping the future of medicine. Providing the missing link between genes and diseases, single-cell atlases make it possible to develop more precise and specific diagnostic tools by understanding the mechanisms of complex diseases.

12 Dec 2022

Many genetic disorders respond well to specialized gene therapy

When the normal DNA sequence in an individual changes or mutates it can cause disease. The mutation may involve multiple genes and may be caused by environmental factors, or there may be chromosomal defects that are harmful at birth, in infancy or environment at a later stage.

12 Dec 2022

Aging influences the diagnosis and treatment of heart attacks in patients over age 75

For people ages 75 and older, age-related changes in general health and in the heart and blood vessels require consideration and likely modifications in how heart attacks and heart disease are treated, according to a new American Heart Association scientific statement published today in the Association's flagship, peer-reviewed journal Circulation.

12 Dec 2022

Muscle News and Research

Developing stem cell sheet for enhancement of angiogenesis which promotes cardiac repair

Study shows how a specific gut microbe-generated byproduct is linked to heart failure risk

Common type 2 diabetes drug requires the presence of GDF15 cytokine to present antidiabetic effects

Trial results confirm the safety of three different Ebola vaccine regimens

High-speed 5G network effective in providing telerehabilitation and teletreatment in remote community

Ceramide blockers prevent the loss of muscle mass during aging in mice

Changing heart cell programming can reverse the lasting damage caused by heart attacks

Researchers discover previously unknown mechanism for how 'starvation response' is triggered

Consumption of artificially sweetened beverages not linked to woman's risk of urinary incontinence

Edible plant-based ink could reduce the cost of cultured meat production

Tiny messenger can be promising candidate for treatment of diseases associated with muscular atrophy

Vitamin D supplements reduce the risk of dynapenia in older people by 78%

Researchers identify molecular determinants of post-infection long-COVID

How human cell atlases provide the missing links between genes, diseases and therapies

Many genetic disorders respond well to specialized gene therapy

Aging influences the diagnosis and treatment of heart attacks in patients over age 75

Researchers seek to reduce Chikungunya virus-caused joint pain with new drug

Study shows how an inflammatory molecule causes life-threatening airway damage in asthma patients

Researchers discover a previously unknown mechanism that drives aging

What is the importance of vitamin B12 supplementation in plant-based diets?

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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