Protein C News and Research

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New study unveils why glioblastoma becomes resistant to treatment

A new study from scientists at the UCLA Health Jonsson Comprehensive Cancer Center helps explain why glioblastoma, one of the most aggressive forms of brain cancer, becomes resistant to treatment, and introduces a new approach that paves the way for more personalized treatment strategies for patients with this deadly brain tumor.

22 Nov 2024

Researchers develop efficient approach for designing custom proteins

Protein design aims to create customized antibodies for therapies, biosensors for diagnostics, or enzymes for chemical reactions.

22 Nov 2024

Cetuximab performs better than durvalumab in treating head and neck cancers

Head and neck cancers are the seventh most common type of cancer worldwide, according to the 2020 World Cancer Report. Smokers and drinkers, as well as those with HPV infections, are disproportionately affected.

22 Nov 2024

SCimilarity revolutionizes single-cell data analysis with rapid cross-tissue comparisons

Researchers developed SCimilarity, a groundbreaking metric-learning framework, to rapidly analyze and compare single-cell data across tissues, diseases, and experimental conditions. This tool enables scalable discovery of shared cellular states and biological insights across the Human Cell Atlas.

21 Nov 2024

Study finds link between poor mental health and browsing negative online content

People with poorer mental health are more prone to browsing negative content online, which further exacerbates their symptoms, finds a study led by UCL researchers.

21 Nov 2024

Breakthrough discovery could lead to novel malaria vaccines and therapies

Malaria, particularly in its severe forms, remains a global health and economic burden. It causes the deaths of more than 600,000 people every year – most of them African children under five.

21 Nov 2024

Small brain-penetrating molecule offers hope for treating aggressive brain tumors

Gliocidin selectively kills glioblastoma cells by inhibiting nucleotide synthesis, showing potential as a therapeutic option in combination with temozolomide.

21 Nov 2024

New molecule promotes gut healing and suppresses tumor growth in colorectal cancer

Researchers at Karolinska Institutet have found a molecule that can both help the intestines to heal after damage and suppress tumor growth in colorectal cancer.

21 Nov 2024

Modified darobactin offers hope for combatting antibiotic-resistant bacteria

Antibacterial drugs are important for treating infections. But increasingly, bacterial resistance to current drugs - so they don't work well, or even at all - means new ones are urgently needed.

21 Nov 2024

Pcdh8 gene suppression critical for zebrafish notochord formation

Can a single protein-encoding gene determine whether a vertebrate embryo develops normally? Yes, according to Osaka Metropolitan University researchers, who found that suppression of Pcdh8 is essential for the notochord to elongate properly in zebrafish.

21 Nov 2024

EZH2 enzyme drives aggressive tumor growth in treatment-resistant prostate cancer

An enzyme called EZH2 has an unexpected role in driving aggressive tumor growth in treatment-resistant prostate cancers, according to a new study by scientists at Weill Cornell Medicine.

20 Nov 2024

CRISPR-based therapy shown to be safe, effective for people with transthyretin amyloidosis

A new type of therapy that 'edits' a gene in patients with a rare heart condition has been shown to be safe and effective, according to research from UCL and the Royal Free Hospital.

20 Nov 2024

Researchers unlock cell density as a tool for building synthetic tissues

Genes aren't the sole driver instructing cells to build multicellular structures, tissues, and organs. In a new paper published in Nature Communications, USC Stem Cell scientist Leonardo Morsut and Caltech computational biologist Matt Thomson characterize the influence of another important developmental driver: cell density, or how loosely or tightly cells are packed into a given space.

20 Nov 2024

New insights into brain aging and Alzheimer's from non-human primates

A new review was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science), on October 29, 2024, Volume 16, Issue 20, titled, "Brain aging and Alzheimer's disease, a perspective from non-human primates."

20 Nov 2024

Researchers uncover hidden roles of accessory genes in SARS-CoV-2

Viruses are lean, mean, infection machines. Their genomes are tiny, usually limited to a handful of absolutely essential genes, and they shed extra genomic deadweight extremely fast.

20 Nov 2024

New approach to stabilize RSV protein could lead to better vaccines

In most people, the lung-infecting pathogens known as respiratory syncytial virus (RSV) and human metapneumovirus (hMPV) trigger mild cold-like symptoms. But in infants and seniors, these viruses can cause severe pneumonia and even death.

20 Nov 2024

Study identifies DNA collisions driving genetic changes in cancer

Cancer researchers at the University of Chicago and the University of California, San Francisco (UCSF) have discovered that mutations in certain genes can lead to the accumulation of DNA errors, resulting in a specific type of genetic change known as large tandem duplications (TDs) that can arise from the collision of two critical cellular processes: transcription and DNA replication.

20 Nov 2024

Protein C News and Research

New study unveils why glioblastoma becomes resistant to treatment

Researchers develop efficient approach for designing custom proteins

Cetuximab performs better than durvalumab in treating head and neck cancers

SCimilarity revolutionizes single-cell data analysis with rapid cross-tissue comparisons

Study finds link between poor mental health and browsing negative online content

Breakthrough discovery could lead to novel malaria vaccines and therapies

Small brain-penetrating molecule offers hope for treating aggressive brain tumors

New molecule promotes gut healing and suppresses tumor growth in colorectal cancer

Modified darobactin offers hope for combatting antibiotic-resistant bacteria

Pcdh8 gene suppression critical for zebrafish notochord formation

EZH2 enzyme drives aggressive tumor growth in treatment-resistant prostate cancer

CRISPR-based therapy shown to be safe, effective for people with transthyretin amyloidosis

Researchers unlock cell density as a tool for building synthetic tissues

New insights into brain aging and Alzheimer's from non-human primates

Researchers uncover hidden roles of accessory genes in SARS-CoV-2

New approach to stabilize RSV protein could lead to better vaccines

Study identifies DNA collisions driving genetic changes in cancer

Antibiotic activity altered by interaction with nanoplastics, new research shows

SARS-CoV-2 hijacks cholesterol trafficking to fuel infection and evade immune responses

Kyushu University team develops antibody to fight age-related muscle atrophy

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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