Therapy News and Research

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Mature motorists worse than younger counterparts when texting while driving

A Wayne State University interdisciplinary research team in the Eugene Applebaum College of Pharmacy and Health Sciences has made a surprising discovery: older, more mature motorists -- who typically are better drivers in many circumstances -- are much worse than their younger counterparts when texting while driving.

18 Dec 2014

Inovio begins hTERT DNA immunotherapy trial in adults with breast, lung and pancreatic cancer

Inovio Pharmaceuticals, Inc. announced it has initiated a phase I trial of its hTERT DNA immunotherapy (INO-1400) alone or in combination with Inovio's IL-12 immune activator (INO-9012) in adults with breast, lung, or pancreatic cancer at high risk of relapse after surgery and other cancer treatments.

18 Dec 2014

Survey highlights need for increased public education on benefits of lung cancer screening in France

A prospective nationwide survey on perceptions of lung cancer in the general population of France highlights a need for increased public education on the benefits of lung cancer screening, the good survival rates of early-stage disease and the improved outcomes with new therapeutic strategies, including targeted-therapies.

18 Dec 2014

Tel Aviv University study throws spotlight on gene mutation responsible for premature ovarian failure

Premature ovarian failure, also known as primary ovarian insufficiency (POI), affects 1% of all women worldwide. In most cases, the exact cause of the condition, which is often associated with infertility, is difficult to determine.

18 Dec 2014

Diabetes drug can boost efficacy of TB medication without causing drug resistance

A more effective treatment for tuberculosis (TB) could soon be available as scientists have discovered that Metformin (MET), a drug for treating diabetes, can also be used to boost the efficacy of TB medication without inducing drug resistance.

17 Dec 2014

Researchers identify 53 existing drugs that may block Ebola virus from entering human cells

Researchers found 53 existing drugs that may keep the Ebola virus from entering human cells, a key step in the process of infection, according to a study led by researchers at the Icahn School of Medicine at Mount Sinai and the National Institutes of Health, and published today in the Nature Press journal Emerging Microbes and Infections.

17 Dec 2014

Metastatic RCC patients may benefit from sequential TKI strategy

For patients with metastatic renal cell carcinoma, sequential tyrosine kinase inhibitor therapy may be better option than changing to a mammalian target of rapamycin inhibitor, research suggests.

17 Dec 2014

RCC renal function independent of axitinib-induced proteinuria

Treatment with the vascular endothelial growth factor receptor inhibitor axitinib does not adversely affect renal function in patients with metastatic renal cell carcinoma even in the presence of proteinuria, a Japanese study indicates.

17 Dec 2014

Antipsychotic polypharmacy prevalent despite efficacy doubts

Results of a retrospective study suggest that around a quarter of patients with schizophrenia receive antipsychotic polypharmacy, despite a lack of evidence for the approach.

17 Dec 2014

Interacting neurodegenerative changes promote Parkinson’s cognitive decline

Research indicates that neurodegeneration in the cholinergic system in the brain is a major contributor to cognitive decline in patients with Parkinson’s disease.

17 Dec 2014

Universal Biosensors announces release of Siemens Xprecia Stride Coagulation Analyzer

Universal Biosensors, Inc. is pleased to announce that Siemens Healthcare Diagnostics Inc. has initiated the European limited release of the Xprecia Stride Coagulation Analyzer, its first point-of-care coagulation testing product.

17 Dec 2014

MU researcher developing nano-scale molecules to image, treat different diseases

Nanomedicine is the medical application of nanotechnology, or the use of microscopic structures to diagnose, image, treat and prevent disease. Current problems in nanomedicine include understanding and anticipating the potentially toxic impact these nanostructures have on the body and the environment once they're released.

17 Dec 2014

Investigational drug increases PFS in patients with advanced breast cancer

In a groundbreaking study that offers new hope for women with advanced breast cancer, researchers from UCLA's Jonsson Comprehensive Cancer Center have published final clinical trial results that showed the amount of time patients were on treatment without their cancer worsening (called progression-free survival) was effectively doubled in women with advanced breast cancer who took the experimental drug palbociclib.

17 Dec 2014

Lilly receives FDA approval for CYRAMZA (ramucirumab)

Eli Lilly and Company has received its third U.S. Food and Drug Administration approval for CYRAMZA (ramucirumab).

16 Dec 2014

Pre-clinical studies confirm TRXE-009 as new potential treatment for melanoma

Novogen Limited, Australian/US biotechnology company, today announces that it has confirmed that its lead candidate product, TRXE-009, originally developed for the treatment of brain cancers, has been shown in pre-clinical studies also to be highly active against melanoma.

16 Dec 2014

CARLINA, Atlangram partner to develop antibiotics for osteoarticular infectious diseases

CARLINA Technologies, a biotechnology company specializing in the development of nanomedicines, today announces the signing of a partnership agreement with Atlangram for the development of innovative pharmaceutical forms of antibiotics for the targeting of osteoarticular infectious diseases.

16 Dec 2014

Curie-Cancer, GamaMabs Pharma extend partnership to develop 3C23K drug for gynecological cancers

Curie-Cancer, the body responsible for developing Institut Curie’s industry partnership activities, and GamaMabs Pharma, a company specialized in the development of monoclonal antibodies for cancer, today announce the extension of their partnership to develop the 3C23K antibody for the treatment of gynecological cancers.

16 Dec 2014

CVRx receives HDE approval for Barostim neo legacy device

CVRx, Inc., a privately held medical device company, announced today that it has received Humanitarian Device Exemption (HDE) approval from the U.S. Food and Drug Administration for its Barostim neo legacy device.

16 Dec 2014

Scientists demonstrate technique for editing genome in sperm-producing adult stem cells

Scientists at Indiana University and colleagues at Stanford and the University of Texas have demonstrated a technique for "editing" the genome in sperm-producing adult stem cells, a result with powerful potential for basic research and for gene therapy.

16 Dec 2014

Novartis announces FDA approval of Signifor LAR for treatment of patients with acromegaly

Novartis announced today that the US Food and Drug Administration has approved Signifor long-acting release (LAR) (pasireotide) for injectable suspension, for intramuscular use, for the treatment of patients with acromegaly who have had an inadequate response to surgery and/or for whom surgery is not an option.

16 Dec 2014

Therapy News and Research

Mature motorists worse than younger counterparts when texting while driving

Inovio begins hTERT DNA immunotherapy trial in adults with breast, lung and pancreatic cancer

Survey highlights need for increased public education on benefits of lung cancer screening in France

Tel Aviv University study throws spotlight on gene mutation responsible for premature ovarian failure

Diabetes drug can boost efficacy of TB medication without causing drug resistance

Researchers identify 53 existing drugs that may block Ebola virus from entering human cells

Metastatic RCC patients may benefit from sequential TKI strategy

RCC renal function independent of axitinib-induced proteinuria

Antipsychotic polypharmacy prevalent despite efficacy doubts

Interacting neurodegenerative changes promote Parkinson’s cognitive decline

Universal Biosensors announces release of Siemens Xprecia Stride Coagulation Analyzer

MU researcher developing nano-scale molecules to image, treat different diseases

Investigational drug increases PFS in patients with advanced breast cancer

Lilly receives FDA approval for CYRAMZA (ramucirumab)

Pre-clinical studies confirm TRXE-009 as new potential treatment for melanoma

CARLINA, Atlangram partner to develop antibiotics for osteoarticular infectious diseases

Curie-Cancer, GamaMabs Pharma extend partnership to develop 3C23K drug for gynecological cancers

CVRx receives HDE approval for Barostim neo legacy device

Scientists demonstrate technique for editing genome in sperm-producing adult stem cells

Novartis announces FDA approval of Signifor LAR for treatment of patients with acromegaly

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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