Cell Death News and Research

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Scientists show how key protein can be important driver of prostate cancer

Scientists at The Wistar Institute have demonstrated how a protein called TRAP1 - an important regulator of energy production in healthy and cancerous cells - is an important driver of prostate cancer and appears to be a valuable therapeutic target for the disease.

9 Nov 2016

SMU virologist receives NCI grant to advance research into how certain viruses cause cancers

SMU virologist and cancer researcher Robert L. Harrod has been awarded a $436,500 grant from the National Cancer Institute to further his lab's research into how certain viruses cause cancers in humans.

8 Nov 2016

Scientists investigate role of mitochondria in Alzheimer's disease pathology

On Nov. 25, 1901, a 51-year-old woman is admitted to a hospital in Frankfurt, Germany, displaying a bizarre constellation of symptoms.

8 Nov 2016

Researchers unravel puzzle of necroptosis

Cell death is an essential physiological process for all multicellular organisms. Throughout life, cells in many tissues die naturally and are replaced by new cells.

8 Nov 2016

Advances in RNA research could pave new way for development of anti-cancer drugs

An international research team led by the University of Leicester has made a breakthrough advance that could pave a new route for the development of anti-cancer drugs.

8 Nov 2016

Regular consumption of dietary emulsifiers promotes colorectal cancer in mice

Emulsifiers, which are added to most processed foods to aid texture and extend shelf life, can alter intestinal bacteria in a manner that promotes intestinal inflammation and colorectal cancer, according to a new study.

7 Nov 2016

Suppressing bone specific protein can alleviate radiotherapy-induced osteoporosis

Radiotherapy destroys cancer cells using high-energy ionizing radiation to damage DNA and induce cell death. About two million patients per year in the United States - more than 50 percent of all cancer patients -- receive radiotherapy at some stage during their illness, either alone or in combination with chemotherapy, surgery, and targeted medicines.

7 Nov 2016

UNC scientists find clue that may help explain why people differ in ability to survive arterial blockages

Researchers at the University of North Carolina School of Medicine have found a major clue that may explain why some people sustain relatively little damage from strokes or heart attacks despite severe arterial blockages.

7 Nov 2016

Llama antibodies can detect cerebral lesions that characterize Alzheimer's disease

The major challenge facing physicians treating Alzheimer's is the ability to detect markers of the disease as early as possible. These markers, located in the brain, are difficult to access, hampering diagnosis.

4 Nov 2016

Researchers create new culture model of human intestine to study inflammatory bowel disease

Inflammatory bowel disease (IBD) is a complex condition that requires a lifetime of care and increases a person's cancer risk.

2 Nov 2016

UGA researchers find new way to improve cancer-killing power of chemotherapy

University of Georgia researchers have found a way to enhance chemotherapy's cancer-killing powers, bringing science one step closer to a more complete cancer treatment.

2 Nov 2016

Researchers identify potential new treatment for brain cancer by targeting genes linked to microcephaly

University of North Carolina Lineberger Comprehensive Cancer Center researchers have identified a potential new treatment for brain cancer by learning from a rare condition that can cause microcephaly.

1 Nov 2016

Research findings may lead to new treatment option for ovarian cancer

A new study has identified an effective combination therapy for treating ovarian cancer cells.

31 Oct 2016

Turning off TAZ protein in liver cells reverses fibrosis in mice

Scientists at Columbia University Medical Center have identified a factor in liver cells that is responsible for turning a relatively benign liver condition, present in 30 percent of U.S. adults, into a serious disease that can lead to liver failure.

27 Oct 2016

Supercomputer simulations of p53 protein could boost future anti-cancer drug discovery

Even though it's almost impossible to see, computational biophysicist Rommie Amaro is using the Stampede supercomputer at the Texas Advanced Computing Center at The University of Texas at Austin to model the largest atomic level system of the tumor suppression protein p53 to date -- over 1.5 million atoms.

27 Oct 2016

Researchers design small compounds with potential to correct mitochondrial dysfunction

Charcot-Marie-Tooth disease is an inherited disorder that leads to a gradual loss of motor neurons and, eventually, paralysis. The condition is caused by genetic mutations that disrupts cells' energy factories, called mitochondria.

25 Oct 2016

Boosting levels of detoxification compound may help prevent metabolic decline linked to aging

Researchers at Oregon State University have found that a specific detoxification compound, glutathione, helps resist the toxic stresses of everyday life - but its levels decline with age and this sets the stage for a wide range of age-related health problems.

24 Oct 2016

Adult brain cells may be vulnerable to Zika infection, new study suggests

Concerns over the Zika virus have focused on pregnant women due to mounting evidence that it causes brain abnormalities in developing fetuses. However, new research in mice from scientists at The Rockefeller University and La Jolla Institute for Allergy and Immunology suggests that certain adult brain cells may be vulnerable to infection as well.

24 Oct 2016

Scientists discover new option for treating malignant pleural mesothelioma

Researchers at the Comprehensive Cancer Center of MedUni Vienna and Vienna General Hospital have discovered a new option for treating malignant pleural mesothelioma.

24 Oct 2016

Novel lipid-based therapeutic shows promise for combating drug resistance in AML

Researchers at the Medical University of South Carolina Hollings Cancer Center have discovered a mechanism that confers resistance to drugs used to treat certain types of acute myeloid leukemia (AML).

24 Oct 2016

Cell Death News and Research

Scientists show how key protein can be important driver of prostate cancer

SMU virologist receives NCI grant to advance research into how certain viruses cause cancers

Scientists investigate role of mitochondria in Alzheimer's disease pathology

Researchers unravel puzzle of necroptosis

Advances in RNA research could pave new way for development of anti-cancer drugs

Regular consumption of dietary emulsifiers promotes colorectal cancer in mice

Suppressing bone specific protein can alleviate radiotherapy-induced osteoporosis

UNC scientists find clue that may help explain why people differ in ability to survive arterial blockages

Llama antibodies can detect cerebral lesions that characterize Alzheimer's disease

Researchers create new culture model of human intestine to study inflammatory bowel disease

UGA researchers find new way to improve cancer-killing power of chemotherapy

Researchers identify potential new treatment for brain cancer by targeting genes linked to microcephaly

Research findings may lead to new treatment option for ovarian cancer

Turning off TAZ protein in liver cells reverses fibrosis in mice

Supercomputer simulations of p53 protein could boost future anti-cancer drug discovery

Researchers design small compounds with potential to correct mitochondrial dysfunction

Boosting levels of detoxification compound may help prevent metabolic decline linked to aging

Adult brain cells may be vulnerable to Zika infection, new study suggests

Scientists discover new option for treating malignant pleural mesothelioma

Novel lipid-based therapeutic shows promise for combating drug resistance in AML

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