Enzyme News and Research

RSS

Stinging nettle extract inhibits SARS-CoV-2 cell fusion

In a recent study posted to the bioRxiv* preprint server, researchers at Ghent University and KU Leuven, Belgium, demonstrated that Urtica dioica agglutinin (UDA), a monomeric lectin extracted from stinging nettle rhizomes, inhibited severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) cell to cell fusion.

12 Jul 2022

SARS-CoV-2 Omicron BA.5 tropism shifting back to ancestral strains

In a recent study posted to the medRxiv* pre-print server, researchers from Australia and Switzerland gathered data to help track and manage ongoing and future infection waves by new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant of concern (VOC) Omicron globally.

12 Jul 2022

Scientists investigate impact of SARS-CoV-2 RBD mutations across variants

In a recent study posted to the medRxiv* pre-print server, Australian researchers comprehensively investigated the impact of 39 receptor-binding-domain (RBD) mutations in six severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) and variants of interest (VOIs).

12 Jul 2022

Persistence of SARS-CoV-2 in tissues leads to long COVID

PASC is likely the result of long-term persistence of SARS-CoV-2 in various tissues

11 Jul 2022

Study reveals sex-based differences in the clinical outcomes of COVID-19 in the US

Researchers investigated sex-based differences among COVID-19 patients in the United States.

11 Jul 2022

SARS-CoV-2 spike protein downregulates ACE2 expression

In a new study, researchers observed the downregulation of ACE2 by SARS-CoV-2.

11 Jul 2022

Study assesses the potential of plant secondary metabolites as potential anti-COVID-19 agents

A new study has focused on identifying plant secondary metabolites (PSM) having a higher affinity for S-RBD of SARS-CoV-2.

11 Jul 2022

Researchers develop a modular software system for optimizing biological systems

Machine learning is transforming all areas of biological science and industry, but is typically limited to a few users and scenarios.

8 Jul 2022

Disrupting genes in the yeast Pichia pastori to increase its secretory production of useful proteins

A collaboration including researchers from Kobe University, University of Tokyo and Tohoku University has successfully identified and disrupted genes in the yeast Pichia pastoris (1) in order to increase its secretory production of useful proteins (2).

8 Jul 2022

Characterization of longer-term effects on behavior and brain inflammation following recovery from mild COVID-19

A recent study reported that long COVID in mice causes brain inflammation and cognitive impairment.

8 Jul 2022

The replicative ability and pathogenicity of Omicron BA.4 and BA.5 isolates in hamsters

Researchers characterized the clinical isolates of SARS-CoV-2 Omicron BA.4 and BA.5.

8 Jul 2022

Study suggests spironolactone may improve clinical outcomes in COVID-19

Researchers performed an integrative analysis of clinical outcomes and viral entry networks in severe COVID-19 infection.

8 Jul 2022

Nanoparticle vaccine could protect against animal viruses including future SARS-CoV-2 variants

A recent study published in the Science journal depicted that mosaic receptor-binding domain (RBD) nanoparticles immunize from diverse sarbecovirus challenges, including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), among animal models.

8 Jul 2022

Discovery of multiple new SARS-CoV-2 MPro inhibitors

In a recent study posted to the bioRxiv* preprint server, researchers performed an extensive library docking for new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease (Mpro) covalent and non-covalent inhibitors.

8 Jul 2022

After 3 doses of COVID vaccine, most cancer patients retain detectable humoral immunity

In a recent study posted to the medRxiv* preprint server, researchers assessed the efficacy and durability of immune responses to the third dose of coronavirus disease 2019 (COVID-19) vaccines. They also assessed the efficacy of the fourth vaccine dose among severely immunocompromised patients with hematological malignancies.

7 Jul 2022

Diabetes patients on Medicare Advantage plans less likely to be prescribed newer, more expensive medicines

While patients with diabetes on Medicare Advantage plans are more likely to receive preventive treatments, they were less likely to be prescribed newer, more expensive medications and were more likely to have higher blood pressure and worse blood glucose control than patients on Medicare Fee-For-Service plans, according to a new study led by a University of Pittsburgh School of Medicine physician-scientist.

7 Jul 2022

Enzyme News and Research

Stinging nettle extract inhibits SARS-CoV-2 cell fusion

SARS-CoV-2 Omicron BA.5 tropism shifting back to ancestral strains

Scientists investigate impact of SARS-CoV-2 RBD mutations across variants

Persistence of SARS-CoV-2 in tissues leads to long COVID

Study reveals sex-based differences in the clinical outcomes of COVID-19 in the US

SARS-CoV-2 spike protein downregulates ACE2 expression

Study assesses the potential of plant secondary metabolites as potential anti-COVID-19 agents

Researchers develop a modular software system for optimizing biological systems

Disrupting genes in the yeast Pichia pastori to increase its secretory production of useful proteins

Characterization of longer-term effects on behavior and brain inflammation following recovery from mild COVID-19

The replicative ability and pathogenicity of Omicron BA.4 and BA.5 isolates in hamsters

Study suggests spironolactone may improve clinical outcomes in COVID-19

Nanoparticle vaccine could protect against animal viruses including future SARS-CoV-2 variants

Discovery of multiple new SARS-CoV-2 MPro inhibitors

After 3 doses of COVID vaccine, most cancer patients retain detectable humoral immunity

Diabetes patients on Medicare Advantage plans less likely to be prescribed newer, more expensive medicines

Researchers find a way to kill recurring prostate cancer with a lot of iron

TRIM7 inhibits coxsackievirus and norovirus infection

2022 monkeypox presents with new symptoms

SARS-CoV-2 RBD vulnerability discovered - target for antibodies against variants

Biochemical Assays for Efficient Hit Prioritization After Screening eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo