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Dominion validates clinical urine drug monitoring assay to detect metabolites of 'herbal incense' product compounds

Dominion Diagnostics has recently developed and validated one of the first clinical urine drug monitoring assays to detect the metabolites of JWH-018 and JWH-073, two compounds typically found in synthetic cannabinoids, also referred to as "herbal incense" products.

20 Sep 2010

Lisofylline drug effective for Type 2 diabetes

Australian scientists, in association with US pharmaceutical company DiaKine Therapeutics, have shown that a drug candidate, Lisofylline, could be useful in treating Type 2 diabetes.

20 Sep 2010

Blood test developed for non-alcoholic fatty liver disease diagnosis

Scientists at the Basque Center for Cooperative Research in Biosciences (CIC bioGUNE) and OWL Genomics Ltd. (Bilbao, Spain), in collaboration with researchers at the INSERM and University Hospitals (APHP Pitié Salpêtrière Hospital, Pierre & Marie Curie University Paris and Centre Hospitalier Universitaire Nice, University of Nice-Sophia-Antipolis, Nice, France), Vanderbilt University (Nashville, US), the University of Southern California (Los Angeles, US), Clinic Hospital and IDIBAPS (Barcelona, Spain) and the Alcalá de Henares University (Alcalá de Henares, Spain) have used metabolomics technology to develop a blood test for non-alcoholic fatty liver disease (NAFLD) diagnosis.

19 Sep 2010

NMS Labs launches method for K2 drug metabolites detection in urine

Of growing concern to public health officials and law enforcement is that routine drug testing cannot detect the use of the popular and highly intoxicating new drugs K2 and Spice. NMS Labs now has a full menu of tests that can detect the use of the designer chemicals present in these products, sold as incense or legal highs. A few weeks ago, NMS Labs launched a blood test to detect a range of these laboratory-designed synthetic drugs.

16 Sep 2010

ABCB4 gene causes bad cholesterol to accumulate in blood: Research

Scientists at the Southwest Foundation for Biomedical Research (SFBR) in San Antonio have found a gene that causes high levels of bad cholesterol to accumulate in the blood as a result of a high-cholesterol diet.

16 Sep 2010

Metabolon receives patent for metabolic age analysis

Metabolon, Inc., leaders in global metabolomics, biomarker discovery and biochemical analysis, announced today the grant of US Patent 7,781,160 entitled "Biomarkers Related to Metabolic Age and Methods Using the Same". The USPTO awarded the patent to Metabolon on August 24, 2010. This is the 12th patent issued to Metabolon.

14 Sep 2010

U of A team on cusp of developing simple predictive test for preeclampsia

A team of researchers from the University of Alberta is on the cusp of developing a simple test to accurately predict which women will develop preeclampsia - a condition that affects 4 million women a year and can result in the deaths of both mothers and their babies.

14 Sep 2010

Researchers identify markers to predict preeclampsia risk in early pregnancy

Researchers identified 14 new markers that could identify in early pregnancy who may be at risk of developing preeclampsia in later pregnancy. An international team of scientists and physicians used a combination of sophisticated emerging technologies and data analysis to detect 14 simple metabolites with high accuracy to predict in early pregnancy which women are at risk of developing preeclampsia in later pregnancy.

14 Sep 2010

MAP Pharmaceuticals reports results from PD trial that compares effects of LEVADEX, IV DHE

MAP Pharmaceuticals, Inc. today reported results from a pharmacodynamics trial comparing the acute effects on pulmonary artery pressure of LEVADEX, dihydroergotamine mesylate administered intravenously and placebo. In the trial, there was no statistically significant difference between the LEVADEX and placebo groups in the primary endpoint of pulmonary artery pressure over two hours after administration.

8 Sep 2010

ProteaBio concludes agreement with George Washington University to commercialize LAESI technology

ProteaBio Europe SAS, a leading developer of new technology, announced today that the company has concluded an exclusive, worldwide license agreement with George Washington University for commercial rights to a new technology that provides rapid identification of a broad range of chemicals and biomolecules.

8 Sep 2010

Researchers reveal new details on bacterial cannibalism

Researchers at the University of California, San Diego have revealed new details about how cannibalistic bacteria identify peers suitable for consumption. The work, which employed imaging mass spectrometry, is a first step toward a broader effort to map all signaling molecules between organisms.

4 Sep 2010

Metabolites in meconium reveal gestational exposure to tobacco smoke: Research

Meconium, the dark and tarry stools passed by a baby during the first few days after birth, can be used to determine how much the mother smoked, or if she was exposed to tobacco smoke during pregnancy.

27 Aug 2010

Scientists create novel map of lipid locations in single cell

In real estate, location is everything. The same might be said of lipids - those crucial cellular fats and oils that serve as building blocks for cells and as key energy sources for the body.In a paper published in the September issue of the Journal of Lipid Research, a team of scientists, led by researchers at the University of California, San Diego School of Medicine, has mapped for the first time the actual locations of specific lipids within a single cell.

26 Aug 2010

FDA approves brand name VELETRI for Actelion's epoprostenol for injection therapy

Actelion Pharmaceuticals US, Inc., today announced that the U.S. Food and Drug Administration has approved the brand name VELETRI® for the company's epoprostenol for injection therapy. VELETRI has been commercially available since April 2010 as Epoprostenol for Injection for the treatment of moderate to severe pulmonary arterial hypertension (PAH) and PAH associated with the scleroderma spectrum of disease. Actelion plans to release VELETRI-labeled product by early fourth quarter of 2010.

26 Aug 2010

Scientists discover Magnetic Resonance Spectroscopy can rapidly diagnose degenerative disorders

Magnetic Resonance Spectroscopy can distinguish between neurological diseases in patients without clear symptoms.A team of American scientists claim that a new method of testing for neurological diseases could provide doctors with a rapid and non-invasively method of diagnosing degenerative disorders.

25 Aug 2010

Prenatal exposure to atrazine leads to prostate inflammation in male rats

A new study shows that male rats prenatally exposed to low doses of atrazine, a widely used herbicide, are more likely to develop prostate inflammation and to go through puberty later than non-exposed animals. The research adds to a growing body of literature on atrazine, an herbicide predominantly used to control weeds and grasses in crops such as corn and sugar cane. Atrazine and its byproducts are known to be relatively persistent in the environment, potentially finding their way into water supplies.

25 Aug 2010

Prenatal pesticide exposure increases susceptibility to ADHD in children

Exposure to organophosphate (OP) pesticides before birth can increase susceptibility to attention disorders such as attention deficit/hyperactivity disorder (ADHD), according to new research published in the journal Environmental Health Perspectives (EHP). The new study is part of a growing body of research indicating that exposure to OP pesticides can adversely affect brain development.

19 Aug 2010

Scientists develop new metabolite analysis technique for accurate ovarian cancer detection

Scientists at the Georgia Institute of Technology have attained very promising results on their initial investigations of a new test for ovarian cancer. Using a new technique involving mass spectrometry of a single drop of blood serum, the test correctly identified women with ovarian cancer in 100 percent of the patients tested. The results can be found online in the journal Cancer Epidemiology, Biomarkers, & Prevention Research.

12 Aug 2010

Magnetic resonance image analysis helps assessment of prostate cancer severity

Rutgers researchers are developing methods that can accurately assess the severity of prostate cancer by analyzing magnetic resonance images and spectra of a patient's prostate gland. This may help physicians decide more confidently which patients need aggressive treatment and which are better served by "watchful waiting," and could even postpone or eliminate invasive biopsies in patients with low-grade tumors.

11 Aug 2010

Thermo Fisher Scientific introduces low evaporation plates for cell culture and high content analysis

Thermo Fisher Scientific Inc., the world leader in serving science, today announced the Thermo Scientific Nunc Edge 96-well Plates for cell-based assays.

From Thermo Fisher Scientific Inc. 29 Jul 2010

Metabolites News and Research

Dominion validates clinical urine drug monitoring assay to detect metabolites of 'herbal incense' product compounds

Lisofylline drug effective for Type 2 diabetes

Blood test developed for non-alcoholic fatty liver disease diagnosis

NMS Labs launches method for K2 drug metabolites detection in urine

ABCB4 gene causes bad cholesterol to accumulate in blood: Research

Metabolon receives patent for metabolic age analysis

U of A team on cusp of developing simple predictive test for preeclampsia

Researchers identify markers to predict preeclampsia risk in early pregnancy

MAP Pharmaceuticals reports results from PD trial that compares effects of LEVADEX, IV DHE

ProteaBio concludes agreement with George Washington University to commercialize LAESI technology

Researchers reveal new details on bacterial cannibalism

Metabolites in meconium reveal gestational exposure to tobacco smoke: Research

Scientists create novel map of lipid locations in single cell

FDA approves brand name VELETRI for Actelion's epoprostenol for injection therapy

Scientists discover Magnetic Resonance Spectroscopy can rapidly diagnose degenerative disorders

Prenatal exposure to atrazine leads to prostate inflammation in male rats

Prenatal pesticide exposure increases susceptibility to ADHD in children

Scientists develop new metabolite analysis technique for accurate ovarian cancer detection

Magnetic resonance image analysis helps assessment of prostate cancer severity

Thermo Fisher Scientific introduces low evaporation plates for cell culture and high content analysis

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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