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Unique pre-clinical model enables study of HIV infection and testing of new therapies

A team led by researchers at Weill Cornell Medicine and Children's National Hospital has developed a unique pre-clinical model that enables the study of long-term HIV infection, and the testing of new therapies aimed at curing the disease.

14 May 2021

Minorities substantially underrepresented in pancreatic cancer clinical trials

Despite the fact that certain racial and ethnic minorities get pancreatic cancer more often, are diagnosed at a younger age and die sooner, clinical trials fail to include representative proportions of non-White patients at every phase of study, according to research that was selected for presentation at Digestive Disease Week 2021.

14 May 2021

Lockdown has encouraged older people to embrace technology, reconnect and build new relationships

The COVID-19 lockdown was a catalyst for many older people to embrace technology, reconnect with friends and build new relationships with neighbors, according to University of Stirling research.

14 May 2021

Farxiga approved in the US for the treatment of chronic kidney disease in patients at risk of progression with and without type-2 diabetes

Approval is the most significant advancement in the treatment of chronic kidney disease in more than 20 years. In DAPA-CKD Phase III trial, Farxiga demonstrated unprecedented reduction in the risk of the composite of worsening of renal function, end-stage kidney disease and cardiovascular or renal death.

From AstraZeneca 14 May 2021

A magnetofluidic platform for SARS-CoV-2 variant and respiratory pathogen detection

Recent research published on the medRxiv* server has developed a portable, magnetofluidic cartridge platform, for automated PCR testing in <30 min, for rapid multiplexed screening of pathogens. A multidisciplinary team of researchers at Johns Hopkins University and the Johns Hopkins University School of Medicine developed these cartridges for multiplexed detection of SARS-CoV-2 with distinctive variant mutations or with Influenza A and B.

13 May 2021

Dominance of South African SARS-CoV-2 variant in the US is unlikely but possible

Researchers in the United States and Canada have conducted a study showing that the South African variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19) – is unlikely to become the dominant strain in the US.

13 May 2021

Study: Duloxetine may reduce cumulative opioid use after total knee arthroplasty

In a study conducted by researchers at Hospital for Special Surgery (HSS), cumulative opioid use was reduced by 30% in a patient group that received duloxetine after total knee arthroplasty (TKA) compared with patients who received placebo.

13 May 2021

UMD receives new funding to stop infection from Lyme disease pathogens before it begins

The University of Maryland received new funding from the Steven & Alexandra Cohen Foundation to develop novel therapeutic strategies that have the potential to stop infection from Lyme disease pathogens before it begins.

13 May 2021

No placental damage observed in case study of pregnant women with mRNA COVID-19 vaccinations

New research by a team at Northwestern University Feinberg School of Medicine, USA, suggests that the COVID-19 vaccine does not damage the placenta and may be safe to use during pregnancy.

13 May 2021

SARS-CoV-2 virus uses a multipronged strategy to avoid detection by the immune system

Severe symptoms of COVID-19, leading often to death, are thought to result from the patient's own acute immune response rather than from damage inflicted directly by the virus.

13 May 2021

Researchers use ultrasound to reduce COVID-19-related inflammation

Researchers at University of California San Diego School of Medicine have begun a pilot clinical trial to test the efficacy of using ultrasound to stimulate the spleen and reduce COVID-19-related inflammation, decreasing the length of hospital stays.

13 May 2021

Comprehensive blood atlas of COVID-19 identifies hallmarks of disease severity

Researchers in the UK have presented a multi-omics integrated blood atlas that delineates the host immune response in patients with coronavirus disease 2019 (COVID-19) of varying severity, providing a unique reference resource for the interpretation of datasets generated from interventional trials.

13 May 2021

Ridiane Denis receives Perkins Award for distinguished service to Boston University

Ridiane Denis, BS, RN, MD, director of clinical research and operations at BU's Clinical & Translational Science Institute, has received a 2021 Perkins Award for distinguished service to the University. Denis is one of three winners of this annual award administered by BU's Faculty Council.

13 May 2021

New study may help develop senolytic drugs that target senescent immune cells

In a study recently published in Nature University of Minnesota Medical School researchers found that senescent immune cells are the most dangerous type of senescent cell.

13 May 2021

International experts are working to provide evidence-based guidelines for radiation therapy dosing for children

Annually, more than 350,000 children in the world are affected by pediatric cancer. Radiation has improved outcomes dramatically, but the damage caused to healthy tissue can affect the long-term health of a child.

13 May 2021

Tympanostomy tubes have no long-term benefits for childhood ear infections

There is no long-term benefit to surgically placing tympanostomy tubes in a young child's ears to reduce the rate of recurrent ear infections during the ensuing two years compared with giving oral antibiotics to treat ear infections, a randomized trial led by UPMC Children's Hospital of Pittsburgh and University of Pittsburgh pediatrician-scientists determined.

13 May 2021

Johns Hopkins expert addresses the impact of pandemic on surgical innovation pipeline and ecosystem

The COVID-19 pandemic has worked havoc on many aspects of society, health care hardly the least among them. In a new study for the journal Surgical Innovation, Associate Professor Toby Gordon of the Johns Hopkins Carey Business School addresses the ways in which the pandemic, as she writes, has "severely weakened the surgical innovation pipeline and ecosystem."

13 May 2021

Medicine News and Research

Unique pre-clinical model enables study of HIV infection and testing of new therapies

Minorities substantially underrepresented in pancreatic cancer clinical trials

Lockdown has encouraged older people to embrace technology, reconnect and build new relationships

Farxiga approved in the US for the treatment of chronic kidney disease in patients at risk of progression with and without type-2 diabetes

A magnetofluidic platform for SARS-CoV-2 variant and respiratory pathogen detection

Dominance of South African SARS-CoV-2 variant in the US is unlikely but possible

Study: Duloxetine may reduce cumulative opioid use after total knee arthroplasty

UMD receives new funding to stop infection from Lyme disease pathogens before it begins

No placental damage observed in case study of pregnant women with mRNA COVID-19 vaccinations

SARS-CoV-2 virus uses a multipronged strategy to avoid detection by the immune system

Researchers use ultrasound to reduce COVID-19-related inflammation

Comprehensive blood atlas of COVID-19 identifies hallmarks of disease severity

Ridiane Denis receives Perkins Award for distinguished service to Boston University

New study may help develop senolytic drugs that target senescent immune cells

International experts are working to provide evidence-based guidelines for radiation therapy dosing for children

Tympanostomy tubes have no long-term benefits for childhood ear infections

Johns Hopkins expert addresses the impact of pandemic on surgical innovation pipeline and ecosystem

Inexpensive test for rapid detection of COVID-19 with 90% accuracy

Research provides new insight into anesthesia-associated tau spreading in the brain

Scientists find dramatic differences between ancient gut microbiomes and modern microbes

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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