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Evolution of SARS-CoV-2 genomes based on continuing positive selection

Researchers hypothesized that ongoing positive selection strongly influences SARS-CoV-2 genomes, which plays an important role in shaping the dynamics of the COVID-19 pandemic.

28 Jun 2022

A data commons to accelerate research in COVID and long-COVID

In a recent study posted to the medRxiv* pre-print server, researchers in the United States developed a pandemic response commons (PRC) called the Chicagoland coronavirus disease 2019 (COVID-19) commons (CCC). The CCC served Chicago, the state of Illinois, and surrounding regions in the United States (US).

28 Jun 2022

Studies discover multiple gene variants that contribute to the risk and severity of NAFLD in children

In a pair of overlapping studies, a diverse team of researchers, led by scientists at University of California San Diego School of Medicine, have deepened investigations into the genetic origins of nonalcoholic fatty liver disease (NAFLD) in children, describing multiple gene variants (including some previously unknown) that contribute to the risk of developing NAFLD and gene variants associated with the severity of the liver disease.

27 Jun 2022

Researchers investigate clinical epidemiological impact of Omicron among hospitalized COVID-19 patients

Researchers assessed the global impact of the emergence of the SARS-CoV-2 Omicron variant on COVID-19 clinical epidemiology among hospitalized patients.

27 Jun 2022

Review and case study illustrates the challenges of monkeypox

A new paper published in Travel Medicine and Infectious Disease reviews the history of this disease in and outside Africa, with special reference to its clinical difficulties.

27 Jun 2022

Comparison of genome sequences of SARS-CoV-2 and other coronaviruses

Researchers compared the genomic sequence of SARS-CoV-2 and that of different coronaviruses.

27 Jun 2022

UC San Diego scientists report on the molecular impact of life indoors

Within and upon every human being reside countless microorganisms - the microbiota that help shape and direct the lives of their hosts. A similar phenomenon occurs between people, microbes and the homes they share.

24 Jun 2022

Scientists identify new genetic disease that delays children's intellectual development

Scientists have identified a new genetic disease, which causes some children's brains to develop abnormally, resulting in delayed intellectual development.

24 Jun 2022

Mapping the trajectory of SARS-CoV-2 evolution inside the host

In a recent study posted to the bioRxiv* pre-print server, researchers in the United States mapped the trajectory of within-host evolution of acute severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

24 Jun 2022

"Founder events" that reduced genetic diversity found to be common throughout human history

Human populations have waxed and waned over the millennia, with some cultures exploding and migrating to new areas or new continents, others dropping to such low numbers that their genetic diversity plummeted.

23 Jun 2022

New method helps unravel three-dimensional structure of the human genome

Weill Cornell Medicine and New York Genome Center researchers, in collaboration with Oxford Nanopore Technologies, have developed a new method to assess on a large scale the three-dimensional structure of the human genome, or how the genome folds.

23 Jun 2022

Inherited mutations in the MINAR2 gene lead to sensorineural deafness

Researchers at the John T. Macdonald Department of Human Genetics and John P. Hussman Institute for Human Genomics at the University of Miami Miller School of Medicine have found that inherited mutations in the MINAR2 gene caused deafness in four families.

23 Jun 2022

Molecular tumor profiling in pediatric cancer patients significantly impacts clinical care

Results of a study of molecular tumor profiling in young patients revealed a high rate of genetic alterations with potential for impacting clinical care, including clarifying diagnoses and treatment with matched, precision cancer drugs.

23 Jun 2022

Scientists reveal mutational frequency in SARS-CoV-2 proteome based on structural characteristics

Scientists have focused on studying the mutational frequency of SARS-CoV-2 proteome based on structural characteristics.

23 Jun 2022

Mutation in SARS-CoV-2 nucleocapsid protein found to enhance replication and pathogenicity

Researchers investigated a highly variable region at residues 203 to 205 in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) nucleocapsid (N) protein.

23 Jun 2022

An integrated molecular diagnostic approach for detecting SARS-CoV-2 variants

Researchers developed an integrated approach combining NGS, molecular barcoding, machine learning, and bioinformatics to enable high-throughput detection of SARS-CoV-2 variants.

23 Jun 2022

Researchers map cancer driver mutations across the human genome

In a recent study published in Nature Biotechnology, researchers explored the causes of cancer by mapping somatic mutation rates across the human genome.

22 Jun 2022

Using omics technology to characterize and quantify biomolecules for better nutrition

Maya Rajasekharan, Senior Advisor, Strategic Program Development at the Alliance of Bioversity International and the International Center for Tropical Agriculture (CIAT), says that food is the single greatest determinant of human health and disease over the course of one's life, and yet a comprehensive understanding of the composition of what we eat remains unknown.

22 Jun 2022

Bacteria causing typhoid fever are highly developing antibiotic resistance

Bacteria causing Typhoid fever are becoming increasingly resistant to some of the most important antibiotics for human health, according to a study published in The Lancet Microbe journal. The largest genome analysis of Salmonella enterica serovar Typhi (S. Typhi) also reveals that resistant strains - almost all originating in South Asia - have spread to other countries nearly 200 times since 1990.

22 Jun 2022

Scientists discover 15 additional genetic mutations linked to KCNK9 imprinting syndrome

A collaborative team of scientists led by Mayo Clinic's Center for Individualized Medicine has discovered 15 additional genetic mutations in the KCNK9 gene that cause a neurodevelopmental syndrome.

21 Jun 2022

Genomic News and Research

Evolution of SARS-CoV-2 genomes based on continuing positive selection

A data commons to accelerate research in COVID and long-COVID

Studies discover multiple gene variants that contribute to the risk and severity of NAFLD in children

Researchers investigate clinical epidemiological impact of Omicron among hospitalized COVID-19 patients

Review and case study illustrates the challenges of monkeypox

Comparison of genome sequences of SARS-CoV-2 and other coronaviruses

UC San Diego scientists report on the molecular impact of life indoors

Scientists identify new genetic disease that delays children's intellectual development

Mapping the trajectory of SARS-CoV-2 evolution inside the host

"Founder events" that reduced genetic diversity found to be common throughout human history

New method helps unravel three-dimensional structure of the human genome

Inherited mutations in the MINAR2 gene lead to sensorineural deafness

Molecular tumor profiling in pediatric cancer patients significantly impacts clinical care

Scientists reveal mutational frequency in SARS-CoV-2 proteome based on structural characteristics

Mutation in SARS-CoV-2 nucleocapsid protein found to enhance replication and pathogenicity

An integrated molecular diagnostic approach for detecting SARS-CoV-2 variants

Researchers map cancer driver mutations across the human genome

Using omics technology to characterize and quantify biomolecules for better nutrition

Bacteria causing typhoid fever are highly developing antibiotic resistance

Scientists discover 15 additional genetic mutations linked to KCNK9 imprinting syndrome

Industry focus eBook: Genomics (4th edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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