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A fast and powerful method for the production of SARS-CoV-2 virus-like particles in insect cells

Researchers presented the direct plasmid transfection method for SARS-CoV-2 virus-like particle production in insect cells and applied the VLPs to evaluate the efficacy of monoclonal antibodies and vaccinated donor sera.

26 Sep 2022

Two waves of Pitx2 expression orchestrate gut rotation during development, study finds

Our guts, and all our organs, are arranged in left-right asymmetric patterns inside our bodies, so that everything may fit.

23 Sep 2022

Only 48% of older adults regularly check their blood pressure at home, study finds

Only 48% of people age 50 to 80 who take blood pressure medications or have a health condition that's affected by hypertension regularly check their blood pressure at home or other places, a new study finds.

23 Sep 2022

Low-cost sensors embedded into t-shirts and face masks to monitor breathing, heart rate

Imperial researchers have embedded new low-cost sensors that monitor breathing, heart rate, and ammonia into t-shirts and face masks.

23 Sep 2022

Study sheds light on how heat stress affects kidney function

Acute kidney injury - defined as an abrupt decline in glomerular filtration rate (GFR) - is among the top causes of hospitalization during a heat wave.

23 Sep 2022

New board members bring significant leadership experience in the biotech sector

Aspect Biosystems, a biotechnology company pioneering the development of bioprinted tissue therapeutics to transform how we treat disease, is pleased to announce the appointment of three new members to its Board of Directors: Dr. Nancy Krieger, Dr. Don Haut, and Dr. Devyn Smith.

From Aspect Biosystems 22 Sep 2022

New modeling system identifies potential therapeutics for autosomal recessive polycystic kidney disease

Organoids - lab grown cells or tissues that resemble organs - serve as a new tool for disease modeling, but researchers often have difficulty replicating the biophysical conditions in which the organs operate within the body.

22 Sep 2022

Large clinical trial compares four drugs commonly used to treat type 2 diabetes

In a large clinical trial that directly compared four drugs commonly used to treat type 2 diabetes, researchers found that insulin glargine and liraglutide performed the best of four medications approved by the U.S. Food and Drug Administration to maintain blood glucose levels in the recommended range.

21 Sep 2022

Study reveals increased immunity evasion by Omicron BA.2.75.2

In a recent study posted to the bioRxiv* preprint server, researchers from ETH Zurich, Imperial College London, and Karolinska Institutet identified increased resistance to antibody-mediated neutralization by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron sublineage BA.2.75.2.

21 Sep 2022

Study identifies genetic variation linked with posterior urethral valves in males

Genetic variation affecting developmental genes not previously linked to urethral development may contribute to a congenital condition that is the most common cause of kidney failure in young males, a study published today in eLife suggests.

20 Sep 2022

Study: Many cardiovascular emergencies are due to poorly controlled hypertension

The top cardiovascular (CVD) diagnoses from U.S. emergency departments suggest that many cardiovascular emergencies are due to poorly controlled high blood pressure, according to a study of more than 20 million emergency department visits published Sept. 8 in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

20 Sep 2022

Researchers reveal native 3D structure of the ciliary base for the first time

Cilia are small hair-like organelles that extend from cells and perform many functions, including motility and signaling.

19 Sep 2022

First multi-center, large-scale registry of severe asthma patients launched in Singapore

A research network formed by Nanyang Technological University, Singapore's (NTU Singapore) Lee Kong Chian School of Medicine (LKCMedicine), Changi General Hospital (CGH), Singapore General Hospital (SGH), and Tan Tock Seng Hospital (TTSH) has set up the Singapore Severe Asthma Registry (SSAR), the first of its kind in the country.

19 Sep 2022

Patients with autoimmune diseases at greater risk of complications after heart attack

In a recent study published in the Journal of the American Heart Association, researchers assessed midterm and management outcomes of acute myocardial infarction (AMI) among patients with rheumatic immune-mediated inflammatory diseases (IMIDs).

18 Sep 2022

Study supports the importance of healthy diet for better cognitive function across races, ethnicities

Dietary choices and their consequences may certainly influence cognitive function. A new study led by investigators at Brigham and Women's Hospital, a founding member of the Mass General Brigham healthcare system, along with outside collaborators expands on previously published work (focused on Puerto Rican individuals in the U.S.) by including additional races and ethnicities.

16 Sep 2022

Study investigates the link between protein intake and skeletal muscle mass in kidney transplant recipients

Conventional wisdom holds that low protein intake is essential for kidney disease patients. However, scientists from Osaka Metropolitan University demonstrated that it might not always be the case with their recent study on the relationship between protein intake and skeletal muscle mass in kidney transplant recipients.

16 Sep 2022

Study identifies a promising target for polycystic kidney disease treatment

Blocking the inhibition of PKD1 and PKD2 gene expression by deleting a binding site for microRNAs hindered the formation and growth of kidney cysts in autosomal dominant polycystic kidney disease (ADPKD) models, UT Southwestern researchers reported.

16 Sep 2022

Higher levels of microbiota engraftment linked to greater chances of transplantation success

From incurable intestinal infections to metabolic syndrome, from melanoma, to chronic inflammatory bowel disease, such as irritable bowel syndrome, to Tourette's syndrome: many diseases can potentially be cured by Fecal Microbiota Transplantation (FMT), and researchers from the Catholic University, Rome and the University of Trento have shown that the greater the level of engraftment of the transplanted microorganisms, the greater the chances of success of the therapy.

15 Sep 2022

Sugar-sweetened beverages increase risk of death from obesity-related cancer

In a large study led by researchers at the American Cancer Society (ACS), men and women who drank two or more servings of sugar-sweetened beverages (SSB) per day, compared to people who never drank, had a five percent increased risk of death from an obesity-related cancer, including gastrointestinal, postmenopausal breast, endometrial and kidney cancer.

15 Sep 2022

Scientists unravel the molecular origin of rare genetic disease cystinosis

The rare genetic disease cystinosis is caused by mutations in the gene for a protein called cystinosin. A team of scientists has now solved the structure of cystinosin and determined how mutations interfere with its normal function, providing insights into the underlying mechanisms and suggesting a way to develop new treatments for the disease.

15 Sep 2022

Kidney News and Research

A fast and powerful method for the production of SARS-CoV-2 virus-like particles in insect cells

Two waves of Pitx2 expression orchestrate gut rotation during development, study finds

Only 48% of older adults regularly check their blood pressure at home, study finds

Low-cost sensors embedded into t-shirts and face masks to monitor breathing, heart rate

Study sheds light on how heat stress affects kidney function

New board members bring significant leadership experience in the biotech sector

New modeling system identifies potential therapeutics for autosomal recessive polycystic kidney disease

Large clinical trial compares four drugs commonly used to treat type 2 diabetes

Study reveals increased immunity evasion by Omicron BA.2.75.2

Study identifies genetic variation linked with posterior urethral valves in males

Study: Many cardiovascular emergencies are due to poorly controlled hypertension

Researchers reveal native 3D structure of the ciliary base for the first time

First multi-center, large-scale registry of severe asthma patients launched in Singapore

Patients with autoimmune diseases at greater risk of complications after heart attack

Study supports the importance of healthy diet for better cognitive function across races, ethnicities

Study investigates the link between protein intake and skeletal muscle mass in kidney transplant recipients

Study identifies a promising target for polycystic kidney disease treatment

Higher levels of microbiota engraftment linked to greater chances of transplantation success

Sugar-sweetened beverages increase risk of death from obesity-related cancer

Scientists unravel the molecular origin of rare genetic disease cystinosis

Event guide: 8th CKD Summit 2026 eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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