RNA News and Research

RSS

Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

Thousands of unique arboviruses and flaviviruses identified from samples collected between 1954-2018

A recent article identifies the encephalitogenic viruses registered in Brazil over the past six decades.

12 Apr 2023

Simple blood test will help neurologists to make a definitive and rapid diagnosis of ALS

ALS is a rare paralytic neurological disease that can impact people in the prime of life. Delays in receiving a definitive diagnosis can be devastating for patients who typically survive only 2–5 years post-diagnosis.

12 Apr 2023

New potential therapeutic developed for diffuse intrinsic pontine glioma using ASO technology

Diffuse intrinsic pontine glioma (DIPG) is a lethal pediatric brain cancer that often kills within a year of diagnosis. Surgery is almost impossible because of the tumors' location.

12 Apr 2023

Transcription of genes is fast but sloppy in old age

In a large joint project, a total of six research groups from the University of Cologne Cluster of Excellence on Cellular Stress Responses in Age-Associated Diseases (CECAD), the Max Planck Institute for Biology of Aging (MPI) in Cologne and the University of Göttingen have demonstrated the following findings which apply across the animal kingdom: with increasing age, the transcriptional elongation speed of genes increases, whereby the quality of the gene products suffers.

12 Apr 2023

Optimized genome-editing method opens the door to more effective treatment of genetic diseases

CRISPR-Cas9 is widely used to edit the genome by studying genes of interest and modifying disease-associated genes.

11 Apr 2023

Cornell receives $9.5 million NIH grant for chronic fatigue research

A Cornell multidisciplinary research center that studies chronic fatigue syndrome has received a five-year, $9.5 million grant from the National Institutes of Health's National Institute of Allergy and Infectious Disease – funding that will enable experts from disparate fields to work together on the mysterious and debilitating condition.

11 Apr 2023

Study expands the knowledge about gut viral diversity in healthy infants

Viruses are usually associated with illness. But our bodies are full of both bacteria and viruses that constantly proliferate and interact with each other in our gastrointestinal tract.

11 Apr 2023

Using tiny bubbles to improve gene therapy

Beyond vaccines, mRNA offers immense potential to fight disease, but targeting the genetic material to specific diseased cells is challenging - requiring a new method.

11 Apr 2023

Immunotherapy response in patients with advanced melanoma depends on prior treatments

Research led by scientists at UCLA Jonsson Comprehensive Cancer Center found that responses to a type of immunotherapy called PD-1 checkpoint blockade in patients with advanced melanoma depended on whether or not they had previously received another immunotherapy – CTLA-4 blockade – as well as other factors.

10 Apr 2023

Study reveals SARS-CoV-2 on hands and frequently-touched surfaces as key predictors of household transmission

A study investigating risk factors and vectors of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) household transmission reveals that the presence of the virus on the hands of primary and secondary cases and on frequently-touched surfaces is associated with transmission risk. The study is published in the journal THE LANCET Microbe.

9 Apr 2023

3D structure of a probable precursor to the CRISPR-Cas12 enzyme revealed

Gene editing is one of the latest breakthroughs in biology. The widely known CRISPR-Cas gene editing system provided prokaryotes (organisms that lack cell nuclei) an immunity against foreign DNA. Since the discovery of the CRISPR gene editing technology, scientists are revealing the evolution of the CRISPR-Cas proteins from their precursors.

7 Apr 2023

Is mRNA decoding in humans structurally and kinetically distinct from bacteria?

Researchers examined molecular-level differences in ribosomal translational fidelity between humans and bacteria.

7 Apr 2023

UW researchers engineer stem cells that do not generate dangerous arrhythmias

Researchers at the University of Washington School of Medicine in Seattle have engineered stem cells that do not generate dangerous arrhythmias, a complication that has to date thwarted efforts to develop stem-cell therapies for injured hearts.

7 Apr 2023

Creation of embryo-like structures from monkey embryonic stem cells for the first time

Human embryo development and early organ formation remain largely unexplored due to ethical issues surrounding the use of embryos for research as well as limited availability of materials to study.

6 Apr 2023

Study sheds new light on the spread of COVID-19 in households

A new Imperial College London-led study provides the first empirical evidence for transmission of SARS-CoV-2 via people's hands and frequently touched household surfaces.

6 Apr 2023

Nasal SARS-CoV-2 vaccine outperforms existing vaccines in preclinical trial

Researchers assess the role of the live-attenuated vaccine sCPD9 in inducing systemic and mucosal immunity against SARS-CoV-2 variants.

6 Apr 2023

Does higher caffeine and coffee intake impact colonic microbiota composition and diversity?

Researchers investigated the association between caffeine and the colonic microbiome.

6 Apr 2023

Omicron BA.5 variant demonstrates increased neuroinvasiveness and pathogenicity in mice

Researchers assessed the extent of SARS-CoV-2 Omicron VOC BA.5 sub-VOC infection-associated brain infection and death.

5 Apr 2023

St. Jude computational biologists characterize the full spectrum of oncogenic fusions in pediatric cancer

The scientific foundation needed to work on curing a class of cancer-causing mutations is here, in the form of a tool from St. Jude Children's Research Hospital.

5 Apr 2023

New method for lower respiratory tract infection diagnosis in critically ill children

Lower respiratory tract infection (LRTI), which includes conditions such as pneumonia, has long been the leading cause of death from communicable agents and a leading cause of death in children worldwide.

5 Apr 2023

RNA News and Research

Further Reading

Thousands of unique arboviruses and flaviviruses identified from samples collected between 1954-2018

Simple blood test will help neurologists to make a definitive and rapid diagnosis of ALS

New potential therapeutic developed for diffuse intrinsic pontine glioma using ASO technology

Transcription of genes is fast but sloppy in old age

Optimized genome-editing method opens the door to more effective treatment of genetic diseases

Cornell receives $9.5 million NIH grant for chronic fatigue research

Study expands the knowledge about gut viral diversity in healthy infants

Using tiny bubbles to improve gene therapy

Immunotherapy response in patients with advanced melanoma depends on prior treatments

Study reveals SARS-CoV-2 on hands and frequently-touched surfaces as key predictors of household transmission

3D structure of a probable precursor to the CRISPR-Cas12 enzyme revealed

Is mRNA decoding in humans structurally and kinetically distinct from bacteria?

UW researchers engineer stem cells that do not generate dangerous arrhythmias

Creation of embryo-like structures from monkey embryonic stem cells for the first time

Study sheds new light on the spread of COVID-19 in households

Nasal SARS-CoV-2 vaccine outperforms existing vaccines in preclinical trial

Does higher caffeine and coffee intake impact colonic microbiota composition and diversity?

Omicron BA.5 variant demonstrates increased neuroinvasiveness and pathogenicity in mice

St. Jude computational biologists characterize the full spectrum of oncogenic fusions in pediatric cancer

New method for lower respiratory tract infection diagnosis in critically ill children

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo