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New therapeutic approach brings hope for treating psoriasis

Disruptive innovations in psoriasis are leading the way at EADV's 29th Congress, EADV Virtual. New data published today shows the first clinical evidence of modulating systemic inflammation by oral delivery of a non-living single strain commensal microbe.

29 Oct 2020

Lianhuaqingwen capsule is effective for treating COVID-19 pneumonia

Lianhuaqingwen (LHQW) capsule, a herb medicine product, has been clinically proved to be effective in coronavirus disease 2019 (COVID-19) pneumonia treatment. However, human exposure to LHQW components and their pharmacological effects remain largely unknown.

28 Oct 2020

DNase coated melanin-like nanospheres for sepsis treatment in severe COVID

As the treatment of severe COVID-19 is very difficult, the researchers from the Korea Research Institute of Biosciences and Biotechnology (KRIBB) suggested that DNase-1 can be utilized to dissolve the neutrophil extracellular traps (NETs), hence halting the further progression of COVID-19.

27 Oct 2020

New research on small non-coding RNAs and SARS-CoV-2

A recently published mini-review in the Frontiers in Microbiology on the altered expression of small non-coding RNAs during coronavirus-mediated infections.

26 Oct 2020

Research uncovers SARS-CoV-2 viral traits critical for the virus in human airways

A new study published on the preprint server bioRxiv* in October 2020 reports the discovery of important viral genomic features that are crucial to its replication in the human airway cells, and its enhancing mutations which increase the rate of replication and determine its target cells.

26 Oct 2020

Burt's Bees announces research data supporting the efficacy of natural lip and anti-aging skincare

Burt's Bees, a pioneer in natural skin care, today announced new research supporting the role of efficacy-first, natural regimens to defend, replenish and restore vibrant, healthier-looking skin.

23 Oct 2020

Dexamethasone drug may not benefit COVID-19 patients with diabetes or low albumin levels

A new discovery about how the body transports dexamethasone, a drug that can increase the survival chances of patients with severe COVID-19, suggests diabetes and other factors may reduce its potentially lifesaving effectiveness.

23 Oct 2020

Biomimetic virus-like particles for safer positive controls in SARS-CoV-2 detection

In an attempt to overcome these issues, a team of researchers from various departments at the University of California San Diego recently proposed using biomimetic virus-like particles (VLPs) as positive controls for assays used in SARS-CoV-2 detection. Their study is published on the preprint server bioRxiv.

23 Oct 2020

DNA vaccine-induced antibodies neutralize SARS-CoV-2

The coronavirus disease (COVID-19) is far from over as the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to ravage across the globe. With the vast spread of the virus, many countries who reported flattening the curve over the past months have reported clusters of new cases and second waves of the outbreak.

22 Oct 2020

Study characterizes biochemical mechanism of cancer-linked enzyme

A new study led by scientists at IUPUI and Indiana University Bloomington is the first to describe a biochemical mechanism that increases the activity of a molecule whose presence is observed in many types of cancer.

21 Oct 2020

Study indicates the relationship between SARS-CoV-2 viral infection and diabetes

It has recently been described that infection by some enteroviruses - a genus of viruses that commonly cause diseases of varying severity - could potentially trigger diabetes, although its direct effect 'in vivo' as well as its mechanism of action at the molecular level were unknown.

21 Oct 2020

Study shows SARS-CoV-2 uses a receptor to efficiently infect human cells

To efficiently infect human cells, SARS-CoV-2, the virus that causes COVID-19, is able to use a receptor called Neuropilin-1, which is very abundant in many human tissues including the respiratory tract, blood vessels and neurons.

21 Oct 2020

Scientists discover mechanism linking gum disease to inflammatory conditions

The link between periodontal (gum) disease and other inflammatory conditions such as heart disease and diabetes has long been established, but the mechanism behind that association has, until now, remained a mystery.

20 Oct 2020

3D imaging of SARS-CoV-2 infection in ferrets using light sheet microscopy

Researchers from the Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health demonstrate the ability to detect severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in 3D tissue samples in ferrets. This will allow the detection of infection patterns in tissues and their interrelations.

20 Oct 2020

New ultrafast 3D clinical imaging system could improve LASIK surgery, diagnosis of eye diseases

LASIK eye surgery - a laser reshaping of the cornea to improve vision - is one of the most popular elective surgeries in the United States, and a University of Houston professor of biomedical engineering intends to improve upon it by giving surgeons more information about the cornea before they begin.

20 Oct 2020

Researchers develop a non-invasive method for measuring thyroid hormone action in tissue

Patients with thyroid dysfunction are routinely treated with drugs to regulate the hormone imbalance. The effect of these drugs is clinically evaluated by means of blood tests.

20 Oct 2020

Researchers develop a molecular docking based webserver to predict drug targets

A highly effective drug therapy is urgently required to combat coronavirus disease 2019 (COVID-19). The authors of this article have developed a molecular docking based webserver, namely D3Targets-2019-nCoV, with two functions, one is for predicting drug targets for drugs or active compounds observed from clinic or in vitro/in vivo studies, the other is for identifying lead compounds against potential drug targets via docking.

20 Oct 2020

Design of an mRNA SARS-CoV-2 vaccine encapsulated in lipid nanoparticles

Now, a new study presented on the preprint server bioRxiv in October 2020 describes the efficient design of an mRNA vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), based on the use of the viral receptor-binding domain (RBD) mRNA encapsulated in lipid nanoparticles (LNP).

19 Oct 2020

New method makes the superficial white matter visible in the living human brain

Traditionally, neuroscience regards the brain as being made up of two basic tissue types. Billions of neurons make up the grey matter, forming a thin layer on the brain's surface.

19 Oct 2020

Tracing lineage to demonstrate direct astrocyte-to-neuron conversion in mouse brain

Regeneration of functional new neurons to repair injured human brain is a long-term unsolved problem up till today.

16 Oct 2020

in vivo News and Research

New therapeutic approach brings hope for treating psoriasis

Lianhuaqingwen capsule is effective for treating COVID-19 pneumonia

DNase coated melanin-like nanospheres for sepsis treatment in severe COVID

New research on small non-coding RNAs and SARS-CoV-2

Research uncovers SARS-CoV-2 viral traits critical for the virus in human airways

Burt's Bees announces research data supporting the efficacy of natural lip and anti-aging skincare

Dexamethasone drug may not benefit COVID-19 patients with diabetes or low albumin levels

Biomimetic virus-like particles for safer positive controls in SARS-CoV-2 detection

DNA vaccine-induced antibodies neutralize SARS-CoV-2

Study characterizes biochemical mechanism of cancer-linked enzyme

Study indicates the relationship between SARS-CoV-2 viral infection and diabetes

Study shows SARS-CoV-2 uses a receptor to efficiently infect human cells

Scientists discover mechanism linking gum disease to inflammatory conditions

3D imaging of SARS-CoV-2 infection in ferrets using light sheet microscopy

New ultrafast 3D clinical imaging system could improve LASIK surgery, diagnosis of eye diseases

Researchers develop a non-invasive method for measuring thyroid hormone action in tissue

Researchers develop a molecular docking based webserver to predict drug targets

Design of an mRNA SARS-CoV-2 vaccine encapsulated in lipid nanoparticles

New method makes the superficial white matter visible in the living human brain

Tracing lineage to demonstrate direct astrocyte-to-neuron conversion in mouse brain

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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