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Antibody cocktail may offer clinical benefit in both prevention and treatment of COVID-19

In June, two studies in Science reported an antibody cocktail against SARS-CoV-2 developed from studies in humanized mice and recovering patients. The two antibody cocktail was designed to bind the virus to reduce the risk of a drug-resistant form emerging.

9 Oct 2020

BioChromato's Smart Evaporator C1 offers safe, efficient concentration of low volume samples

BioChromato Inc. reports how the Department of Bioimaging Information Analysis at Gunma University is benefiting from the ability of its Smart Evaporator C1 to safely and efficiently concentrate low volume samples.

From BioChromato Inc. 9 Oct 2020

Scientists recreate initial steps of HIV infection in a test tube

Accomplishing a feat that had been a pipe dream for decades, scientists have recreated in a test tube the first steps of infection by HIV (human immunodeficiency virus), the virus that causes AIDS (acquired immunodeficiency syndrome).

9 Oct 2020

Researchers apply CRISPR technology to eliminate fusion genes present in tumor cells

The CRISPR/Cas9 gene-editing tool is one of the most promising approaches to advancing treatments of genetic diseases - including cancer -, an area of research where progress is constantly being made.

9 Oct 2020

Laser irradiation shows promise as a new treatment modality for osteoporosis

Osteoporosis is a disease in which bone loses mass as a result of age or other influences. This weakening is the leading cause of fractures in the elderly, often after trivial injuries, and makes treating these "pathological fractures" a challenge.

8 Oct 2020

Researchers create p16-Cre ERT2 -tdTomato mouse model to characterize in vivo senescent cells

Cell senescence is a state of permanent cell cycle arrest that was initially defined for cells grown in cell culture. It plays a key role in age-associated organ dysfunction and age-related diseases such as cancer, but the in vivo pathogenesis is largely unclear.

7 Oct 2020

A new technology to measure lens stiffness associated with presbyopia

A University of Houston biomedical researcher is developing new technology that will measure the stiffness of the lens in the eye, which is likely associated with presbyopia, or farsightedness, the inevitable and age-related loss of the ability to focus on nearby objects.

6 Oct 2020

Optimized low‐dose drug combinations to effectively treat colorectal cancer

Chemotherapy-based cancer treatment has distressing side effects for patients and increases the risk of developing resistance to the treatment.

6 Oct 2020

Dried plum diet prevents spinal cord injury‐related bone loss

Findings from a new study among mice show a diet high in dried plum (prunes) completely prevents bone loss associated with spinal cord injury (SCI), while also restoring some of the bone lost following SCI.

6 Oct 2020

Midges and mosquitoes unlikely to spread SARS-CoV-2

A recent study published on the preprint server bioRxiv* in September 2020 looked to see if biting insects pose a risk for transmission of SARS-CoV-2 to humans or animals following a SARS-CoV-2 infected blood meal.

5 Oct 2020

Anti-sense agents suppress SARS-CoV-2 virus

Researchers in the United States have conducted a study showing that anti-sense agents called peptide-conjugated morpholino oligomers (PPMOs) have the ability to specifically and potently suppress the growth of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent responsible for the current coronavirus disease 2019 (COVID-19) pandemic.

4 Oct 2020

PATH wins grant to develop oral treatment option for soil-transmitted helminth infections

PATH announced today they received a grant from Japan's Global Health Innovative Technology Fund to develop a new oral treatment option for soil-transmitted helminth infections.

1 Oct 2020

A detailed map of latent virus reservoir in individuals with HIV

The latent reservoir is the last bastion of HIV's resistance to a cure. But it is difficult to destroy because it is invisible: the cells in the reservoir harbor virus that is dormant, so they don't have any viral proteins on their surface that would give them away.

30 Sep 2020

SARS-CoV-2 D614G variant enhances infectivity, replication and transmission

Researchers in the United States and Japan have conducted a study showing a common mutation in the spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) - the agent that causes coronavirus disease 2019 (COVD-19) - enhances the infectivity, replication, and early transmission of the virus.

30 Sep 2020

FUJIFILM Irvine Scientific to exclusively distribute chemically defined substrate for stem cell culture

FUJIFILM Irvine Scientific today announced that it has become the exclusive, worldwide distributor of cellnest®, a recombinant peptide attachment substrate.

From FUJIFILM Irvine Scientific 30 Sep 2020

A TLR2 agonist reduces SARS-CoV-2 in upper respiratory tract of ferret model

In a recent bioRxiv* preprint paper, Professor Miles W. Carroll et al. study an agonist for reducing the SARS-CoV-2's viral load. They show that prophylactic intra-nasal administration of TLR2/6 (toll-like receptor) agonist, INNA-051, reduces viral RNA in the nose and throat, in a ferret model.

30 Sep 2020

New graphical tool to identify potent neutralizing antibodies against SARS-CoV-2

A new study by researchers at the Indian Institute of Science and the University of Queensland and published on the preprint server medRxiv in September 2020 discusses using a novel tool to identify the most effective among currently known anti-SARS-CoV-2 NAbs.

29 Sep 2020

New study shows efficacy of carbon nanotube implants to restore motor functions

A new study conducted by SISSA and the University of Trieste shows the efficacy of carbon nanotube implants to restore motor functions and paves the way for a new therapeutic approach for spinal cord injuries.

29 Sep 2020

Special formulation of inhaled niclosamide may be effective against SARS-CoV-2

Now in new research published on the preprint server bioRxix*, a novel formulation of the drug Niclosamide (NIC) is observed to be effective against SARS-CoV-2 and MERS-CoV in mouse models; it also protects against methicillin-resistance Staphylococcus aureus pneumonia and inflammatory lung damage.

28 Sep 2020

Human recombinant soluble ACE2 successfully used in a patient with severe COVID-19

A multinational research group recently published a paper in the journal Lancet Respiratory Medicine which describes the first patient with a severe form of coronavirus disease (COVID-19) that was successfully treated with human recombinant soluble ACE2.

27 Sep 2020

in vivo News and Research

Antibody cocktail may offer clinical benefit in both prevention and treatment of COVID-19

BioChromato's Smart Evaporator C1 offers safe, efficient concentration of low volume samples

Scientists recreate initial steps of HIV infection in a test tube

Researchers apply CRISPR technology to eliminate fusion genes present in tumor cells

Laser irradiation shows promise as a new treatment modality for osteoporosis

Researchers create p16-Cre ERT2 -tdTomato mouse model to characterize in vivo senescent cells

A new technology to measure lens stiffness associated with presbyopia

Optimized low‐dose drug combinations to effectively treat colorectal cancer

Dried plum diet prevents spinal cord injury‐related bone loss

Midges and mosquitoes unlikely to spread SARS-CoV-2

Anti-sense agents suppress SARS-CoV-2 virus

PATH wins grant to develop oral treatment option for soil-transmitted helminth infections

A detailed map of latent virus reservoir in individuals with HIV

SARS-CoV-2 D614G variant enhances infectivity, replication and transmission

FUJIFILM Irvine Scientific to exclusively distribute chemically defined substrate for stem cell culture

A TLR2 agonist reduces SARS-CoV-2 in upper respiratory tract of ferret model

New graphical tool to identify potent neutralizing antibodies against SARS-CoV-2

New study shows efficacy of carbon nanotube implants to restore motor functions

Special formulation of inhaled niclosamide may be effective against SARS-CoV-2

Human recombinant soluble ACE2 successfully used in a patient with severe COVID-19

eBook: Using iPSCs models for human disease research and drug discovery eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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