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RNA-binding protein needed for development of pathological hypertrophy

In response to conditions such as high blood pressure and reduced blood flow to cardiac muscle, the adult heart can drastically enlarge, a process called pathological hypertrophy that preserves cardiac function in the short term but predisposes patients to intractable heart failure and sudden cardiac death if left untreated.

31 Jan 2019

Study sheds light on the genetic causes of tumors in salivary glands

Acinic cell carcinoma is the third most common malignant form of salivary gland cancer. These tumors are similar to normal salivary gland tissue and occur most frequently in the parotid gland.

31 Jan 2019

New autism mouse model shows how epigenetic regulation impacts downstream gene

The causes of autism spectrum disorder are diverse and to some extent, unknown. But without doubt, they are complex, layered and deeply nuanced.

31 Jan 2019

Study opens new avenue for treating ulcerative colitis or Crohn's disease

An international study led by the Complutense University of Madrid (UCM) and the National Centre for Cardiovascular Research (CNIC) has found that Lactobacillus bacteria present in the intestinal microbiota interact with immune system cells to strengthen the intestinal barrier.

31 Jan 2019

UCLA-led scientists discover new clues to what goes wrong in the brains of people with autism

A team of UCLA-led scientists has discovered important clues to what goes wrong in the brains of people with autism -- a developmental disorder with no cure and for which scientists have no deep understanding of what causes it.

31 Jan 2019

Vaccination with live S. mitis may offer protection from Streptococcus pneumoniae

Vaccinating laboratory mice with Streptococcus mitis bacteria prevents their virulent sibling, Streptococcus pneumoniae from infecting the mice.

30 Jan 2019

Leukemia promotes premature aging in the bone marrow

Leukemia promotes premature aging in healthy bone marrow cells - according to new research from the University of East Anglia.

30 Jan 2019

Novel 3D imaging method reveals how pancreatic cancers originate

A new technique to study tissue samples in 3D has revealed that pancreatic cancers can start and grow in two distinct ways, solving a decades-old mystery of how tumors form.

From The Francis Crick Institute 30 Jan 2019

FSU study breaks new ground in the battle against malignant pediatric brain cancers

Scientists are making important progress in the battle against a class of devilishly complex human pediatric brain cancers thanks to a new study from a team of Florida State University students and faculty.

30 Jan 2019

Climate change linked to increase in congenital heart defects

Rising temperatures stemming from global climate change may increase the number of infants born with congenital heart defects in the United States over the next two decades and may result in as many as 7,000 additional cases over an 11 year-period in eight representative states, according to new research in the Journal of the American Heart Association, the Open Access Journal of the American Heart Association/American Stroke Association.

30 Jan 2019

Expediting HPLC Method Development in Pharmaceutical Analysis

In this interview, Michael Dong discusses stability-indicating methods such as UHPLC, in pharmaceutical analysis. At Pittcon, Michael will introduce a 3-pronged template approach to HPLC method development.

From Pittcon 30 Jan 2019

Researchers discover how transcription factors find specific loci within DNA

Bioengineering experts have discovered that transcription factors which bind non-specifically to mitotic chromosomes are more efficient at finding their binding site within DNA during interphase.

30 Jan 2019

Promega signs license agreement with Broad Institute to access CRISPR-Cas9 technology

Promega announce non-exclusive license agreement with the Broad Institute of MIT and Harvard to sell tools and reagents for CRISPR-Cas9 gene editing.

From Promega Corporation 30 Jan 2019

Corning Life Sciences to highlight advanced 3D cell culture technologies and tools at SLAS 2019

Corning Incorporated will showcase advanced 3D cell culture technologies and workflow solutions, and including those for high throughput screening and ADME/toxicology at SLAS 2019.

From Corning Life Sciences 30 Jan 2019

Sphere Fluidics announces closure of $2 million (circa £1.5 million) investment round

Sphere Fluidics announced today that is has closed a $2 million (circa £1.5 million) investment round.

From Society for Laboratory Automation and Screening (SLAS) 30 Jan 2019

Sphere Fluidics and PAA collaborate to offer automated micro-plate handling capabilities for single cell analysis

Sphere Fluidics, a company commercializing single cell analysis systems underpinned by its patented picodroplet technology, and Peak Analysis and Automation, a leader in the industry for the design and manufacture of automated laboratory equipment, will collaborate to offer automated micro-plate handling capabilities for single cell analysis.

30 Jan 2019

Using bivalves as model organisms offers promising avenues for medical research

Shellfish like oysters and mussels have the potential to revolutionize human health research, according to a new paper in Developmental and Comparative Immunology.

30 Jan 2019

Vitamin D may lower glucose levels and reduce risk of developing type 2 diabetes

The benefits of vitamin D in promoting bone health are already well known. A new study out of Brazil suggests that vitamin D also may promote greater insulin sensitivity, thus lowering glucose levels and the risk of developing type 2 diabetes.

30 Jan 2019

Dietary fiber polymers can influence gut environment through physical forces

Large molecules from dietary fiber, called polymers, can physically influence the environment in the small intestine by causing solid particles to group together (or aggregate), according to research published in eLife.

30 Jan 2019

Researchers identify effects of nanoparticles on intestinal microorganisms

The intestinal microbiome is not only key for food processing but an accepted codeterminant for various diseases. Researchers led by the University Medical Center of Johannes Gutenberg University Mainz identified effects of nanoparticles on intestinal microorganisms.

29 Jan 2019

B Cell News and Research

RNA-binding protein needed for development of pathological hypertrophy

Study sheds light on the genetic causes of tumors in salivary glands

New autism mouse model shows how epigenetic regulation impacts downstream gene

Study opens new avenue for treating ulcerative colitis or Crohn's disease

UCLA-led scientists discover new clues to what goes wrong in the brains of people with autism

Vaccination with live S. mitis may offer protection from Streptococcus pneumoniae

Leukemia promotes premature aging in the bone marrow

Novel 3D imaging method reveals how pancreatic cancers originate

FSU study breaks new ground in the battle against malignant pediatric brain cancers

Climate change linked to increase in congenital heart defects

Expediting HPLC Method Development in Pharmaceutical Analysis

Researchers discover how transcription factors find specific loci within DNA

Promega signs license agreement with Broad Institute to access CRISPR-Cas9 technology

Corning Life Sciences to highlight advanced 3D cell culture technologies and tools at SLAS 2019

Sphere Fluidics announces closure of $2 million (circa £1.5 million) investment round

Sphere Fluidics and PAA collaborate to offer automated micro-plate handling capabilities for single cell analysis

Using bivalves as model organisms offers promising avenues for medical research

Vitamin D may lower glucose levels and reduce risk of developing type 2 diabetes

Dietary fiber polymers can influence gut environment through physical forces

Researchers identify effects of nanoparticles on intestinal microorganisms

Using single B cell screening to boost antibody discovery eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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