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Study identifies a potential pharmacological target for treating COVID-19-associated heart failure

Researchers at the University of Maryland School of Medicine's (UMSOM) Center for Precision Disease Modeling identified how a specific protein in SARS-CoV-2, the virus responsible for COVID-19, damages heart tissue. They then used a drug to reverse the toxic effects of that protein on the heart.

8 Nov 2022

SARS-CoV-2 activates NLRP3 inflammasome

Researchers assessed the role of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the NLR family pyrin domain containing 3 (NLRP3) inflammasome activation.

7 Nov 2022

Environmental toxicants contribute to obesity and metabolic disease

In a recent study published in the Current Opinion in Pharmacology journal, researchers assessed the impact of environmental toxicants and brown adipose tissue (BAT) on obesity and metabolic disorders.

4 Nov 2022

Circadian disruption induces weight gain through changes in gut microbiota

In a recent study published in the journal Molecular Metabolism, researchers investigated the impact of environmental and genetic disruptions of the circadian rhythms on the peripheral circadian clock synchronization and microbiome oscillations in the gastrointestinal tract.

3 Nov 2022

Study highlights the benefits of eccentric-focused training

Good news for those who struggle to fit a gym workout into their day: you may be able to cut your weights routine in half and still see the same results.

3 Nov 2022

Researchers corroborate the importance of exercise for cognitive function

Accumulating evidence finds that exercise can improve brain function and delay or prevent the onset of neurodegenerative diseases such as Alzheimer's and Parkinson's disease.

2 Nov 2022

Higher viscosity of extracellular fluid enhances cancer dissemination

New research findings show how higher viscosity, or resistance to flow, of the extracellular fluid that surrounds cells enables cancer cells to migrate more rapidly from a primary tumor to other sites in the body.

2 Nov 2022

Study identifies a root cause of chronic heart failure following a heart attack

A multi-institution study led by Rohan Dharmakumar, PhD, of Indiana University School of Medicine, has identified that iron drives the formation of fatty tissue in the heart and leads to chronic heart failure in about fifty percent of heart attack survivors.

1 Nov 2022

New control system could be used to finely tune the production of useful proteins

Using an approach based on CRISPR proteins, MIT researchers have developed a new way to precisely control the amount of a particular protein that is produced in mammalian cells.

1 Nov 2022

New analysis on the risk for myocarditis or pericarditis after mRNA COVID-19 vaccination

A comprehensive review and meta-analysis of published research confirm that young adults (40 years old and younger) have a slightly elevated risk for myocarditis or pericarditis after mRNA COVID-19 vaccination.

1 Nov 2022

Novel troponin test may help improve the treatment of heart attack patients

A new test has been developed in Turku, Finland, that helps in separating heart attack patients from those whose cardiac troponin values are elevated due to renal insufficiency.

1 Nov 2022

Increasing Awareness Surrounding Ataxia

In this interview, we speak to Dr. Lauren Moore from the National Ataxia Foundation about the condition and the importance of raising awareness for ataxia.

31 Oct 2022

Huntington's disease impairs autophagy in older patients

Huntington's disease, a fatal, inherited neurodegenerative condition, is caused by a genetic error present at birth, though its symptoms often don't begin until middle adulthood.

28 Oct 2022

Researchers discover how hydroquinine inhibits major drug-resistant bacteria

Researchers say hydroquinine could be an effective weapon against a germ that can cause serious infections in humans, mostly hospital patients

28 Oct 2022

Wireless, battery-free pacemaker could make life easier for heart disease patients

Atrial fibrillation – a form of irregular heartbeat, or arrhythmia – leads to more than 454,000 hospitalizations and nearly 160,000 deaths in the United States each year. Globally, it is estimated that approximately 60 million people are affected by the condition.

28 Oct 2022

AI models improve the accuracy of diagnosing coronary artery disease

Several recent discoveries show that the accuracy of diagnosing coronary artery disease and predicting patient risk is improved with the help of artificial intelligence (AI) models developed by scientists in the Division of Artificial Intelligence in Medicine at Cedars-Sinai.

28 Oct 2022

Researchers unravel the precise mechanism of nuclear envelope repair in human and mouse cells

All living cells harbor nuclei - key biological structures that play an important role in information storage, retrieval, and duplication of genetic information.

28 Oct 2022

New studies point to a broadly applicable treatment for neurodegenerative diseases

Two new studies from Washington University School of Medicine in St. Louis support development of a broadly applicable treatment for neurodegenerative diseases that targets a molecule that serves as the central executioner in the death of axons, the wiring of the nervous system.

26 Oct 2022

Probiotics and prebiotics can reduce the risk of frailty syndrome among the elderly

New research found that the intestinal microbiome plays a critical role in the metabolic processes that affect cognition, body composition, and immune function.

26 Oct 2022

What is the association of self-reported post-vaccination symptoms with anti–SARS-CoV-2 antibody response?

Researchers investigated the association of symptoms after COVID-19 vaccination with antibody responses against SARS-CoV-2.

26 Oct 2022

Muscle News and Research

Study identifies a potential pharmacological target for treating COVID-19-associated heart failure

SARS-CoV-2 activates NLRP3 inflammasome

Environmental toxicants contribute to obesity and metabolic disease

Circadian disruption induces weight gain through changes in gut microbiota

Study highlights the benefits of eccentric-focused training

Researchers corroborate the importance of exercise for cognitive function

Higher viscosity of extracellular fluid enhances cancer dissemination

Study identifies a root cause of chronic heart failure following a heart attack

New control system could be used to finely tune the production of useful proteins

New analysis on the risk for myocarditis or pericarditis after mRNA COVID-19 vaccination

Novel troponin test may help improve the treatment of heart attack patients

Increasing Awareness Surrounding Ataxia

Huntington's disease impairs autophagy in older patients

Researchers discover how hydroquinine inhibits major drug-resistant bacteria

Wireless, battery-free pacemaker could make life easier for heart disease patients

AI models improve the accuracy of diagnosing coronary artery disease

Researchers unravel the precise mechanism of nuclear envelope repair in human and mouse cells

New studies point to a broadly applicable treatment for neurodegenerative diseases

Probiotics and prebiotics can reduce the risk of frailty syndrome among the elderly

What is the association of self-reported post-vaccination symptoms with anti–SARS-CoV-2 antibody response?

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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