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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

Diverse subset of T-cell clones plays a role in the antitumor effects of immune checkpoint inhibitors

Immune checkpoint inhibitors (ICIs) are widely sought after for the treatment of different types of cancers. Unfortunately, only 20–30% patients with cancer respond to ICI treatment.

29 Mar 2023

Synthetic hydrogel-based lymphoma tumor model paves way for personalized cancer therapies

In recent years, innovative cancer drugs that target specific molecular drivers of the disease have been embraced as the treatment of choice for many types of cancer.

29 Mar 2023

SARS-CoV-2 infection disrupts the RNA modifications, study reports

Coronavirus disease (COVID-19) hijacks parts of infected cells' vital RNA machinery, thereby blocking important functions in the cells. These damaging changes in the RNA can likely be reversed, potentially leading to new drugs against COVID-19, University of Gothenburg researchers show.

29 Mar 2023

An apple a day keeps the doctor away: polyphenol-enriched apples alter immune cell gene expression and fecal microbiota composition

Researchers compared the effects of consuming red-fleshed apples and white-fleshed among healthy adults.

29 Mar 2023

Study links altered gut microbiome to allergies in infants raised under COVID-19 lockdown

A recent study posted to medRxiv* preprint server revealed that gut microbiome predicts atopic outcomes in infants with decreased bacterial exposure.

28 Mar 2023

COVID-19 activates endogenous retroviruses within our genome

Researchers assess the impact of SARS-CoV-2 infection on endogenous retroviruses of the LTR69 subfamily.

28 Mar 2023

Grape polyphenols reduce angiogenesis in adipose tissue during overfeeding weight gain

A study published in the Journal of Nutritional Biochemistry investigated the changes in gene expressions during an overfeeding episode. It demonstrated that supplementation of grape polyphenols in healthy lean men modulates the expression of genes related to adipose tissue angiogenesis.

28 Mar 2023

Study shows how RNA biomarkers may be used to confirm heart disease

When patients begin to experience chest pain or shortness of breath while exercising, doctors may struggle to correctly diagnose if the problem is caused by coronary artery disease.

28 Mar 2023

What is the effect of prior BCG vaccination on the immunogenicity and efficacy of subsequent COVID-19 vaccination?

Researchers assessed the impact of BCG vaccination on the protection provided by SARS-CoV-2 vaccination.

28 Mar 2023

What is the relationship between a plant-based diet and the gut microbiome?

A recent study conducted a systematic review of the impact of plant-based diets on gut microbiota.

28 Mar 2023

Using a long-read approach to gain better understanding of DNA mutations in cancer genomes

Looking to learn more from genomics sequencing about DNA mutations and cancer, researchers applied a long-read approach to get a broader genomic view.

27 Mar 2023

Epigenome reprogramming after SARS-CoV-2 infection

Researchers performed a 3D evaluation of SARS-CoV-2 infected human cells.

27 Mar 2023

UQ researchers lead new study on bacteria that cause sepsis

University of Queensland researchers have led a national study on the four main bacteria that cause sepsis, providing new targets for developing antibiotics.

27 Mar 2023

Advancements in understanding and treating breast cancer

Researchers describe recent advancements in breast cancer research.

26 Mar 2023

Antibodies produced by newly developed mRNA vaccines are transferred from pregnant rabbits to offspring

Newly developed mRNA vaccines against Zika virus and HIV-1 produced strong antibody responses that transferred from pregnant rabbits to their offspring, researchers report March 24th in the journal Molecular Therapy.

24 Mar 2023

Study outlines a meta-scale approach to quantifying the human proteome

A major puzzle of biology is that while the human genome contains roughly 20,000 genes, many comparatively primitive organisms - including the universally-studied worm C. elegans - have almost the same number of genes.

23 Mar 2023

Dampened mucosal response against SARS-CoV-2 in pregnant individuals

In a recent study posted to the medRxiv* preprint server, researchers examined associations between coronavirus disease 2019 (COVID-19) outcomes and mucosal antibody responses against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and viral RNA levels in pregnant individuals.

22 Mar 2023

Novel subset of memory B cells predicts long-lived antibody responses to influenza vaccination

Memory B cells play a critical role to provide long-term immunity after a vaccination or infection. In a study published in the journal Immunity, researchers describe a distinct and novel subset of memory B cells that predict long-lived antibody responses to influenza vaccination in humans.

22 Mar 2023

Researchers discover how a mutation in the desmosomal gene leads to arrhythmogenic cardiomyopathy

Mutations in genes that form the desmosome are the most common cause of the cardiac disease arrhythmogenic cardiomyopathy (ACM), which affects one in 2000 to 5000 people worldwide.

22 Mar 2023

Discovery of 16th century coronavirus in France

In a recent study published in the International Journal of Infectious Diseases, researchers conducted paleoserological tests on dental pulp samples of skeletons excavated from the Abbey Saint-Pierre in the village of Baume-Les-Messieurs in France.

20 Mar 2023

RNA News and Research

Further Reading

Diverse subset of T-cell clones plays a role in the antitumor effects of immune checkpoint inhibitors

Synthetic hydrogel-based lymphoma tumor model paves way for personalized cancer therapies

SARS-CoV-2 infection disrupts the RNA modifications, study reports

An apple a day keeps the doctor away: polyphenol-enriched apples alter immune cell gene expression and fecal microbiota composition

Study links altered gut microbiome to allergies in infants raised under COVID-19 lockdown

COVID-19 activates endogenous retroviruses within our genome

Grape polyphenols reduce angiogenesis in adipose tissue during overfeeding weight gain

Study shows how RNA biomarkers may be used to confirm heart disease

What is the effect of prior BCG vaccination on the immunogenicity and efficacy of subsequent COVID-19 vaccination?

What is the relationship between a plant-based diet and the gut microbiome?

Using a long-read approach to gain better understanding of DNA mutations in cancer genomes

Epigenome reprogramming after SARS-CoV-2 infection

UQ researchers lead new study on bacteria that cause sepsis

Advancements in understanding and treating breast cancer

Antibodies produced by newly developed mRNA vaccines are transferred from pregnant rabbits to offspring

Study outlines a meta-scale approach to quantifying the human proteome

Dampened mucosal response against SARS-CoV-2 in pregnant individuals

Novel subset of memory B cells predicts long-lived antibody responses to influenza vaccination

Researchers discover how a mutation in the desmosomal gene leads to arrhythmogenic cardiomyopathy

Discovery of 16th century coronavirus in France

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