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Full assembly of human chromosome 8 reveals novel genes, disease risks

The full assembly of human chromosome 8 is reported this week in Nature. While on the outside this chromosome looks typical, being neither short nor long or distinctive, its DNA content and arrangement are of interest in primate and human evolution, in several immune and developmental disorders, and in chromosome sequencing structure and function generally.

8 Apr 2021

Study offers a promising blood test for depression, bipolar disorder

Worldwide, 1 in 4 people will suffer from a depressive episode in their lifetime. While current diagnosis and treatment approaches are largely trial and error, a breakthrough study by Indiana University School of Medicine researchers sheds new light on the biological basis of mood disorders, and offers a promising blood test aimed at a precision medicine approach to treatment.

8 Apr 2021

Moderate cycling during dialysis could improve the heart health of patients with kidney failure

Cycling at moderate intensity during dialysis could drastically improve the heart health of patients with kidney failure and result in significant savings for the NHS, according to new research by the University of Leicester supported by the charity Kidney Research UK and National Institute for Health Research Leicester Biomedical Research Centre.

8 Apr 2021

Phase 2 clinical trial launched in Thailand to evaluate IL-15 agonist as therapy to reduce HIV reservoir

The U.S. Military HIV Research Program (MHRP) at the Walter Reed Army Institute of Research last week launched a Phase 2 clinical trial in Thailand to evaluate an interleukin-15 (IL-15) superagonist, ImmunityBio's Anktiva (also called N-803), administered during acute HIV infection as an experimental therapy to target establishment of the HIV reservoir at a very early stage.

8 Apr 2021

Mutations to autism-associated gene cause a cascade of problems in developing mouse brains

Damage to the autism-associated gene Dyrk1a, sets off a cascade of problems in developing mouse brains, resulting in abnormal growth-factor signaling, undergrowth of neurons, smaller-than-average brain size, and, eventually, autism-like behaviors, a new study from Scripps Research, Florida, finds.

8 Apr 2021

Holocaust survivors have lingering health impacts

The damaging effects of life under Nazi rule have long been known with many victims having experienced periods of protracted emotional and physical torture, malnutrition and mass exposure to disease.

8 Apr 2021

Study: Heart failure and stroke are on the rise in men below 40 years of age

Heart failure and stroke are unusual diagnoses among younger people. But they are now clearly on the rise in men below the age of 40, according to a University of Gothenburg study.

8 Apr 2021

Study links chronic sinus inflammation with alterations in brain activity

The millions of people who have chronic sinusitis deal not only with stuffy noses and headaches, they also commonly struggle to focus, and experience depression and other symptoms that implicate the brain's involvement in their illness.

8 Apr 2021

IRB Barcelona researchers find the Achilles heel of some lung tumors

In cancer, personalized medicine takes advantage of the unique genetic changes in an individual tumor to find its vulnerabilities and fight it.

8 Apr 2021

Hispanic immigrants of working age more likely to die of COVID-19 than non-Hispanics

Hispanic immigrants of working age -- 20 to 54 years old -- are over 11 times more likely to die of COVID-19 than U.S.-born men and women who are not Hispanic, according to a USC study of California death certificate data from 2020.

8 Apr 2021

USC Stem Cell scientist receives $2.56 million NIH grant to explore 'synthetic' embryonic development

Whether in an earthworm or a human being, developmental processes are driven by complex networks of genetically-encoded signals that enable cells to take cues from each other and their environment.

8 Apr 2021

Moderna COVID-19 vaccine ensures long-term protection against SARS-CoV-2 infection, suggests study

A recent report published in the New England Journal of Medicine has revealed that the COVID-19 vaccine developed by Moderna, Inc, USA, is capable of inducing robust and durable antibody responses for at least six months post-vaccination.

8 Apr 2021

Targeted therapy achieves excellent outcomes, reduces side effects in high-risk Hodgkin lymphoma

Scientists are reporting results of the first frontline clinical trial to use targeted therapy to treat high-risk pediatric Hodgkin lymphoma.

8 Apr 2021

Thermo Fisher Scientific launches in-air SARS-CoV-2 surveillance solution

Thermo Fisher Scientific Inc., the world leader in serving science, today announced the launch of the Thermo Scientific AerosolSense Sampler, a new surveillance solution designed to deliver fast and highly reliable insight into the presence of in-air pathogens, including SARS-CoV-2.

From Thermo Fisher Scientific – Pharmaceutical and Biopharmaceutical Solutions 8 Apr 2021

Heart failure and stroke are on the rise in men below the age of 40, finds study

Heart failure and stroke are unusual diagnoses among younger people. But they are now clearly on the rise in men below the age of 40, according to a University of Gothenburg study. The scientists have found links to obesity and low fitness in the upper teens.

8 Apr 2021

Eliminating racism and anti-LGBTQ policies can improve the health of black sexual minority men

Eliminating racist and anti-LGBTQ policies is essential to improving the health of Black gay, bisexual and other sexual minority men, according to a Rutgers-led research team.

8 Apr 2021

Mouse monoclonal antibodies protect against SARS-CoV-2 wildtype, UK and South African variants

A new preprint research paper posted to the bioRxiv server reports on the ability of a set of neutralizing mouse antibodies to protect mice against multiple lineages of SARS-CoV-2.

8 Apr 2021

Microrna-29 molecule controls brain maturation in mammals

A team led by scientists at the UNC School of Medicine identified a molecule called microRNA-29 as a powerful controller of brain maturation in mammals. Deleting microRNA-29 in mice caused problems very similar to those seen in autism, epilepsy, and other neurodevelopmental conditions.

8 Apr 2021

Hydrogels offer new hope for cancer treatment

Hydrogels are often used as drug delivery systems, but to be effective carriers for anti-cancer drugs, they need to be responsive to varied stimuli in the tumor microenvironment.

8 Apr 2021

Study: H2AK119ub1 is necessary for maternal inheritance of H3K27me3

An epigenetic study at the RIKEN Center for Integrative Medical Sciences shows that in mouse egg cells, modifications to histone H2A at lysine 119 lay the groundwork for inherited DNA functional modifications from the mother.

8 Apr 2021

Medicine News and Research

Full assembly of human chromosome 8 reveals novel genes, disease risks

Study offers a promising blood test for depression, bipolar disorder

Moderate cycling during dialysis could improve the heart health of patients with kidney failure

Phase 2 clinical trial launched in Thailand to evaluate IL-15 agonist as therapy to reduce HIV reservoir

Mutations to autism-associated gene cause a cascade of problems in developing mouse brains

Holocaust survivors have lingering health impacts

Study: Heart failure and stroke are on the rise in men below 40 years of age

Study links chronic sinus inflammation with alterations in brain activity

IRB Barcelona researchers find the Achilles heel of some lung tumors

Hispanic immigrants of working age more likely to die of COVID-19 than non-Hispanics

USC Stem Cell scientist receives $2.56 million NIH grant to explore 'synthetic' embryonic development

Moderna COVID-19 vaccine ensures long-term protection against SARS-CoV-2 infection, suggests study

Targeted therapy achieves excellent outcomes, reduces side effects in high-risk Hodgkin lymphoma

Thermo Fisher Scientific launches in-air SARS-CoV-2 surveillance solution

Heart failure and stroke are on the rise in men below the age of 40, finds study

Eliminating racism and anti-LGBTQ policies can improve the health of black sexual minority men

Mouse monoclonal antibodies protect against SARS-CoV-2 wildtype, UK and South African variants

Microrna-29 molecule controls brain maturation in mammals

Hydrogels offer new hope for cancer treatment

Study: H2AK119ub1 is necessary for maternal inheritance of H3K27me3

Everything there is to know about biosimilars eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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